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Items: 9


HuR-targeted small molecule inhibitor exhibits cytotoxicity towards human lung cancer cells.

Muralidharan R, Mehta M, Ahmed R, Roy S, Xu L, Aubé J, Chen A, Zhao YD, Herman T, Ramesh R, Munshi A.

Sci Rep. 2017 Aug 30;7(1):9694. doi: 10.1038/s41598-017-07787-4.


Folate receptor-targeted nanoparticle delivery of HuR-RNAi suppresses lung cancer cell proliferation and migration.

Muralidharan R, Babu A, Amreddy N, Basalingappa K, Mehta M, Chen A, Zhao YD, Kompella UB, Munshi A, Ramesh R.

J Nanobiotechnology. 2016 Jun 21;14(1):47. doi: 10.1186/s12951-016-0201-1.


PKM2 uses control of HuR localization to regulate p27 and cell cycle progression in human glioblastoma cells.

Mukherjee J, Ohba S, See WL, Phillips JJ, Molinaro AM, Pieper RO.

Int J Cancer. 2016 Jul 1;139(1):99-111. doi: 10.1002/ijc.30041. Epub 2016 Mar 2.


HuR-targeted nanotherapy in combination with AMD3100 suppresses CXCR4 expression, cell growth, migration and invasion in lung cancer.

Muralidharan R, Panneerselvam J, Chen A, Zhao YD, Munshi A, Ramesh R.

Cancer Gene Ther. 2015 Dec;22(12):581-90. doi: 10.1038/cgt.2015.55. Epub 2015 Oct 23.


The Expression of CUGBP1 After Spinal Cord Injury in Rats.

Yang L, Zhang J, Chen J, Jin H, Liu J, Huang S, Cui Z.

Neurochem Res. 2015 Sep;40(9):1966-75. doi: 10.1007/s11064-015-1692-0. Epub 2015 Aug 18.


Embryonic lethal abnormal vision-like HuR-dependent mRNA stability regulates post-transcriptional expression of cyclin-dependent kinase inhibitor p27Kip1.

Ziegeler G, Ming J, Koseki JC, Sevinc S, Chen T, Ergun S, Qin X, Aktas BH.

J Biol Chem. 2010 May 14;285(20):15408-19. doi: 10.1074/jbc.M110.113365. Epub 2010 Mar 23.


Structure and activity of the internal ribosome entry site within the human p27 Kip1 5'-untranslated region.

Coleman J, Miskimins WK.

RNA Biol. 2009 Jan-Mar;6(1):84-9. Epub 2009 Jan 5.


ELAV/Hu proteins inhibit p27 translation via an IRES element in the p27 5'UTR.

Kullmann M, Göpfert U, Siewe B, Hengst L.

Genes Dev. 2002 Dec 1;16(23):3087-99.


A U-rich element in the 5' untranslated region is necessary for the translation of p27 mRNA.

Millard SS, Vidal A, Markus M, Koff A.

Mol Cell Biol. 2000 Aug;20(16):5947-59.

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