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Items: 1 to 20 of 23

1.

Novel microtubule inhibitor MPT0B098 inhibits hypoxia-induced epithelial-to-mesenchymal transition in head and neck squamous cell carcinoma.

Tsai IT, Kuo CC, Liou JP, Chang JY.

J Biomed Sci. 2018 Mar 28;25(1):28. doi: 10.1186/s12929-018-0432-6.

2.

Cytoplasmic overexpression of RNA-binding protein HuR is a marker of poor prognosis in meningioma, and HuR knockdown decreases meningioma cell growth and resistance to hypoxia.

Gauchotte G, Hergalant S, Vigouroux C, Casse JM, Houlgatte R, Kaoma T, Helle D, Brochin L, Rech F, Peyre M, Labrousse F, Vallar L, Guéant JL, Vignaud JM, Battaglia-Hsu SF.

J Pathol. 2017 Aug;242(4):421-434. doi: 10.1002/path.4916. Epub 2017 Jul 5.

PMID:
28493484
3.

MiR675-5p Acts on HIF-1α to Sustain Hypoxic Responses: A New Therapeutic Strategy for Glioma.

Lo Dico A, Costa V, Martelli C, Diceglie C, Rajata F, Rizzo A, Mancone C, Tripodi M, Ottobrini L, Alessandro R, Conigliaro A.

Theranostics. 2016 May 8;6(8):1105-18. doi: 10.7150/thno.14700. eCollection 2016.

4.

Multifaceted roles of HSF1 in cancer.

Jiang S, Tu K, Fu Q, Schmitt DC, Zhou L, Lu N, Zhao Y.

Tumour Biol. 2015 Jul;36(7):4923-31. doi: 10.1007/s13277-015-3674-x. Epub 2015 Jun 25. Review.

PMID:
26108999
5.

Redox regulation of genome stability by effects on gene expression, epigenetic pathways and DNA damage/repair.

Mikhed Y, Görlach A, Knaus UG, Daiber A.

Redox Biol. 2015 Aug;5:275-89. doi: 10.1016/j.redox.2015.05.008. Epub 2015 Jun 3. Review.

6.

HIF-inducible miR-191 promotes migration in breast cancer through complex regulation of TGFβ-signaling in hypoxic microenvironment.

Nagpal N, Ahmad HM, Chameettachal S, Sundar D, Ghosh S, Kulshreshtha R.

Sci Rep. 2015 Apr 13;5:9650. doi: 10.1038/srep09650.

7.

Chemopreventive apigenin controls UVB-induced cutaneous proliferation and angiogenesis through HuR and thrombospondin-1.

Tong X, Mirzoeva S, Veliceasa D, Bridgeman BB, Fitchev P, Cornwell ML, Crawford SE, Pelling JC, Volpert OV.

Oncotarget. 2014 Nov 30;5(22):11413-27.

8.

Hsp70-Bag3 interactions regulate cancer-related signaling networks.

Colvin TA, Gabai VL, Gong J, Calderwood SK, Li H, Gummuluru S, Matchuk ON, Smirnova SG, Orlova NV, Zamulaeva IA, Garcia-Marcos M, Li X, Young ZT, Rauch JN, Gestwicki JE, Takayama S, Sherman MY.

Cancer Res. 2014 Sep 1;74(17):4731-40. doi: 10.1158/0008-5472.CAN-14-0747. Epub 2014 Jul 3.

9.

Cell type-specific reciprocal regulation of HIF1A gene expression is dependent on 5'- and 3'-UTRs.

Yasuda M, Hatanaka T, Shirato H, Nishioka T.

Biochem Biophys Res Commun. 2014 May 16;447(4):638-43. doi: 10.1016/j.bbrc.2014.04.058. Epub 2014 Apr 21.

PMID:
24769203
10.

Pleiotropic effects of methionine adenosyltransferases deregulation as determinants of liver cancer progression and prognosis.

Frau M, Feo F, Pascale RM.

J Hepatol. 2013 Oct;59(4):830-41. doi: 10.1016/j.jhep.2013.04.031. Epub 2013 May 7. Review.

11.

MPT0B098, a novel microtubule inhibitor that destabilizes the hypoxia-inducible factor-1α mRNA through decreasing nuclear-cytoplasmic translocation of RNA-binding protein HuR.

Cheng YC, Liou JP, Kuo CC, Lai WY, Shih KH, Chang CY, Pan WY, Tseng JT, Chang JY.

Mol Cancer Ther. 2013 Jul;12(7):1202-12. doi: 10.1158/1535-7163.MCT-12-0778. Epub 2013 Apr 25. Erratum in: Mol Cancer Ther. 2013 Sep;12(9):1919.

12.

HIF-1α protein is upregulated in HIF-2α depleted cells via enhanced translation.

Schulz K, Milke L, Rübsamen D, Menrad H, Schmid T, Brüne B.

FEBS Lett. 2012 Jun 4;586(11):1652-7. doi: 10.1016/j.febslet.2012.04.039. Epub 2012 May 2.

13.

Heat shock transcription factor Hsf1 is involved in tumor progression via regulation of hypoxia-inducible factor 1 and RNA-binding protein HuR.

Gabai VL, Meng L, Kim G, Mills TA, Benjamin IJ, Sherman MY.

Mol Cell Biol. 2012 Mar;32(5):929-40. doi: 10.1128/MCB.05921-11. Epub 2012 Jan 3. Erratum in: Mol Cell Biol. 2017 Sep 26;37(20):.

14.

Opposite functions of HIF-α isoforms in VEGF induction by TGF-β1 under non-hypoxic conditions.

Chae KS, Kang MJ, Lee JH, Ryu BK, Lee MG, Her NG, Ha TK, Han J, Kim YK, Chi SG.

Oncogene. 2011 Mar 10;30(10):1213-28. doi: 10.1038/onc.2010.498. Epub 2010 Nov 8.

PMID:
21057546
15.

Overexpression of the RNA binding protein HuR impairs tumor growth in triple negative breast cancer associated with deficient angiogenesis.

Gubin MM, Calaluce R, Davis JW, Magee JD, Strouse CS, Shaw DP, Ma L, Brown A, Hoffman T, Rold TL, Atasoy U.

Cell Cycle. 2010 Aug 15;9(16):3337-46. doi: 10.4161/cc.9.16.12711. Epub 2010 Aug 17.

16.

RNA-binding proteins implicated in the hypoxic response.

Masuda K, Abdelmohsen K, Gorospe M.

J Cell Mol Med. 2009 Sep;13(9A):2759-69. doi: 10.1111/j.1582-4934.2009.00842.x. Epub 2009 Jul 6. Review.

17.

von Hippel-Lindau tumor suppressor gene-dependent mRNA stabilization of the survival factor parathyroid hormone-related protein in human renal cell carcinoma by the RNA-binding protein HuR.

Danilin S, Sourbier C, Thomas L, Rothhut S, Lindner V, Helwig JJ, Jacqmin D, Lang H, Massfelder T.

Carcinogenesis. 2009 Mar;30(3):387-96. doi: 10.1093/carcin/bgn275. Epub 2008 Dec 4.

PMID:
19056930
18.

Expression of vascular endothelial growth factor-A and mRNA stability factor HuR in human astrocytic tumors.

Ido K, Nakagawa T, Sakuma T, Takeuchi H, Sato K, Kubota T.

Neuropathology. 2008 Dec;28(6):604-11. doi: 10.1111/j.1440-1789.2008.00926.x. Epub 2008 May 21.

PMID:
18498284
19.

Multiple pathways are involved in the anoxia response of SKIP3 including HuR-regulated RNA stability, NF-kappaB and ATF4.

Rzymski T, Paantjens A, Bod J, Harris AL.

Oncogene. 2008 Jul 31;27(33):4532-43. doi: 10.1038/onc.2008.100. Epub 2008 Apr 14.

PMID:
18408768
20.

RNA-binding proteins HuR and PTB promote the translation of hypoxia-inducible factor 1alpha.

Galbán S, Kuwano Y, Pullmann R Jr, Martindale JL, Kim HH, Lal A, Abdelmohsen K, Yang X, Dang Y, Liu JO, Lewis SM, Holcik M, Gorospe M.

Mol Cell Biol. 2008 Jan;28(1):93-107. Epub 2007 Oct 29.

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