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Items: 1 to 20 of 104


CD40L Priming of Platelets via NF-κB Activation is CD40- and TAK1-Dependent.

Kojok K, Akoum SE, Mohsen M, Mourad W, Merhi Y.

J Am Heart Assoc. 2018 Dec 4;7(23):e03677. doi: 10.1161/JAHA.118.009636.


Corrigendum: Semaphorin 4C: A Novel Component of B-Cell Polarization in Th2-Driven Immune Responses.

Xue D, Desjardins M, Kaufman GN, Béland M, Al-Tamemi S, Ahmed E, Tao S, Friedel RH, Mourad W, Mazer BD.

Front Immunol. 2017 Mar 8;8:213. doi: 10.3389/fimmu.2017.00213. eCollection 2017.


Peripherally Generated Foxp3+ Regulatory T Cells Mediate the Immunomodulatory Effects of IVIg in Allergic Airways Disease.

Massoud AH, Kaufman GN, Xue D, Béland M, Dembele M, Piccirillo CA, Mourad W, Mazer BD.

J Immunol. 2017 Apr 1;198(7):2760-2771. doi: 10.4049/jimmunol.1502361. Epub 2017 Feb 20.


Semaphorin 4C: A Novel Component of B-Cell Polarization in Th2-Driven Immune Responses.

Xue D, Desjardins M, Kaufman GN, Béland M, Al-Tamemi S, Ahmed E, Tao S, Friedel RH, Mourad W, Mazer BD.

Front Immunol. 2016 Dec 7;7:558. doi: 10.3389/fimmu.2016.00558. eCollection 2016. Erratum in: Front Immunol. 2017 Mar 08;8:213.


Constitutively active Stat5b signaling confers tolerogenic functions to dendritic cells of NOD mice and halts diabetes progression.

Zerif E, Maalem A, Gaudreau S, Guindi C, Ramzan M, Véroneau S, Gris D, Stankova J, Rola-Pleszczynski M, Mourad W, Dupuis G, Amrani A.

J Autoimmun. 2017 Jan;76:63-74. doi: 10.1016/j.jaut.2016.09.001. Epub 2016 Sep 12.


The Interaction of CD154 with the α5β1 Integrin Inhibits Fas-Induced T Cell Death.

Bachsais M, Naddaf N, Yacoub D, Salti S, Alaaeddine N, Aoudjit F, Hassan GS, Mourad W.

PLoS One. 2016 Jul 8;11(7):e0158987. doi: 10.1371/journal.pone.0158987. eCollection 2016.


Ochratoxin A mediates MAPK activation, modulates IL-2 and TNF-α mRNA expression and induces apoptosis by mitochondria-dependent and mitochondria-independent pathways in human H9 T cells.

Darif Y, Mountassif D, Belkebir A, Zaid Y, Basu K, Mourad W, Oudghiri M.

J Toxicol Sci. 2016;41(3):403-16. doi: 10.2131/jts.41.403.


Involvement of the cytoplasmic cysteine-238 of CD40 in its up-regulation of CD23 expression and its enhancement of TLR4-triggered responses.

Nadiri A, Jundi M, El Akoum S, Hassan GS, Yacoub D, Mourad W.

Int Immunol. 2015 Nov;27(11):555-65. doi: 10.1093/intimm/dxv030. Epub 2015 May 14.


Role of CD154 in cancer pathogenesis and immunotherapy.

Hassan GS, Stagg J, Mourad W.

Cancer Treat Rev. 2015 May;41(5):431-40. doi: 10.1016/j.ctrv.2015.03.007. Epub 2015 Mar 26. Review.


Interaction of CD154 with different receptors and its role in bidirectional signals.

Alturaihi H, Hassan GS, Al-Zoobi L, Salti S, Darif Y, Yacoub D, El Akoum S, Oudghiri M, Merhi Y, Mourad W.

Eur J Immunol. 2015 Feb;45(2):592-602. doi: 10.1002/eji.201444941. Epub 2014 Dec 16.


Enhancement of Rituximab-induced cell death by the physical association of CD20 with CD40 molecules on the cell surface.

Al-Zoobi L, Salti S, Colavecchio A, Jundi M, Nadiri A, Hassan GS, El-Gabalawy H, Mourad W.

Int Immunol. 2014 Aug;26(8):451-65. doi: 10.1093/intimm/dxu046. Epub 2014 May 15.


Coexpression of TLR2 or TLR4 with HLA-DR potentiates the superantigenic activities of Mycoplasma arthritidis-derived mitogen.

Shio MT, Hassan GS, Shah WA, Nadiri A, El Fakhry Y, Li H, Mourad W.

J Immunol. 2014 Mar 15;192(6):2543-50. doi: 10.4049/jimmunol.1300591. Epub 2014 Feb 3.


Lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) in acute coronary syndrome: relationship with low-density lipoprotein cholesterol.

Jabor B, Choi H, Ruel I, Hafiane A, Mourad W, Genest J.

Can J Cardiol. 2013 Dec;29(12):1679-86. doi: 10.1016/j.cjca.2013.09.026. Epub 2013 Oct 2.


Dendritic cell immunoreceptor: a novel receptor for intravenous immunoglobulin mediates induction of regulatory T cells.

Massoud AH, Yona M, Xue D, Chouiali F, Alturaihi H, Ablona A, Mourad W, Piccirillo CA, Mazer BD.

J Allergy Clin Immunol. 2014 Mar;133(3):853-63.e5. doi: 10.1016/j.jaci.2013.09.029. Epub 2013 Nov 8.


CD154 is released from T-cells by a disintegrin and metalloproteinase domain-containing protein 10 (ADAM10) and ADAM17 in a CD40 protein-dependent manner.

Yacoub D, Benslimane N, Al-Zoobi L, Hassan G, Nadiri A, Mourad W.

J Biol Chem. 2013 Dec 13;288(50):36083-93. doi: 10.1074/jbc.M113.506220. Epub 2013 Nov 4.


HLA-DO increases bacterial superantigen binding to human MHC molecules by inhibiting dissociation of class II-associated invariant chain peptides.

Pezeshki AM, Azar GA, Mourad W, Routy JP, Boulassel MR, Denzin LK, Thibodeau J.

Hum Immunol. 2013 Oct;74(10):1280-7. doi: 10.1016/j.humimm.2013.05.010. Epub 2013 Jun 10.


CD154: the atherosclerotic risk factor in rheumatoid arthritis?

Hassan GS, Yacoub D, Alaaeddine N, Nadiri A, Merhi Y, Mourad W.

Arthritis Res Ther. 2013 Feb 22;15(1):206. doi: 10.1186/ar4153. Review.


Soluble CD40 ligand impairs the anti-platelet function of peripheral blood angiogenic outgrowth cells via increased production of reactive oxygen species.

Bou Khzam L, Hachem A, Zaid Y, Boulahya R, Mourad W, Merhi Y.

Thromb Haemost. 2013 May;109(5):940-7. doi: 10.1160/TH12-09-0679. Epub 2013 Feb 21.


Requirement of transmembrane domain for CD154 association to lipid rafts and subsequent biological events.

Benslimane N, Hassan GS, Yacoub D, Mourad W.

PLoS One. 2012;7(8):e43070. doi: 10.1371/journal.pone.0043070. Epub 2012 Aug 14.


Involvement of nuclear factor κB in platelet CD40 signaling.

Hachem A, Yacoub D, Zaid Y, Mourad W, Merhi Y.

Biochem Biophys Res Commun. 2012 Aug 17;425(1):58-63. doi: 10.1016/j.bbrc.2012.07.049. Epub 2012 Jul 20.


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