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Items: 1 to 20 of 59

1.

Generation and characterization of avian-derived anti-human CD19 single chain fragment antibodies.

Tsai KC, Chiang CW, Lo YN, Chang FL, Lin TY, Chang CY, Chen WC, Lee YC.

Anim Biotechnol. 2019 Oct;30(4):293-301. doi: 10.1080/10495398.2018.1486323. Epub 2018 Sep 27.

PMID:
30261812
2.

GSK-3 inhibition through GLP-1R allosteric activation mediates the neurogenesis promoting effect of P7C3 after cerebral ischemic/reperfusional injury in mice.

Wang YH, Liou KT, Tsai KC, Liu HK, Yang LM, Chern CM, Shen YC.

Toxicol Appl Pharmacol. 2018 Oct 15;357:88-105. doi: 10.1016/j.taap.2018.08.023. Epub 2018 Sep 4.

PMID:
30189238
3.

New Hirsutinolide-Type Sesquiterpenoids from Vernonia cinerea Inhibit Nitric Oxide Production in LPS-Stimulated RAW264.7 Cells.

Kuo LY, Tseng PY, Lin YC, Liaw CC, Zhang LJ, Tsai KC, Lin ZH, Ho HO, Kuo YH.

Planta Med. 2018 Dec;84(18):1348-1354. doi: 10.1055/a-0647-1901. Epub 2018 Jul 9.

PMID:
29986352
4.

Protein-DNA complex-guided discovery of the antibacterial lead E1 for restoring the susceptibility of Klebsiella Pneumoniae to polymyxin B by targeting the response regulator PmrA.

Tseng TS, Tu IF, Chen HT, Lin LC, Tsai KC, Wu SH, Chen C.

Chem Commun (Camb). 2018 Jun 14;54(49):6372-6375. doi: 10.1039/c8cc01840e.

PMID:
29869651
5.

Interaction of S17 Antibody with the Functional Binding Region of the Hepatitis B Virus Pre-S2 Epitope.

Chang CY, Chang FL, Chiang CW, Lo YN, Lin TY, Chen WC, Tsai KC, Lee YC.

Viral Immunol. 2018 Sep;31(7):492-499. doi: 10.1089/vim.2017.0200. Epub 2018 May 30.

PMID:
29847243
6.

Acylguanidine derivatives of zanamivir and oseltamivir: Potential orally available prodrugs against influenza viruses.

Hsu PH, Chiu DC, Wu KL, Lee PS, Jan JT, Cheng YE, Tsai KC, Cheng TJ, Fang JM.

Eur J Med Chem. 2018 Jun 25;154:314-323. doi: 10.1016/j.ejmech.2018.05.030. Epub 2018 May 21.

PMID:
29843102
7.

Peramivir conjugates as orally available agents against influenza H275Y mutant.

Wang PC, Chiu DC, Jan JT, Huang WI, Tseng YC, Li TT, Cheng TJ, Tsai KC, Fang JM.

Eur J Med Chem. 2018 Feb 10;145:224-234. doi: 10.1016/j.ejmech.2017.12.072. Epub 2017 Dec 24.

PMID:
29324342
8.

Peramivir analogues bearing hydrophilic side chains exhibit higher activities against H275Y mutant than wild-type influenza virus.

Chiu DC, Lin TC, Huang WI, Cheng TJ, Tsai KC, Fang JM.

Org Biomol Chem. 2017 Nov 29;15(46):9910-9922. doi: 10.1039/c7ob02374j.

PMID:
29159346
9.

Protein disulfide isomerase a4 acts as a novel regulator of cancer growth through the procaspase pathway.

Kuo TF, Chen TY, Jiang ST, Chen KW, Chiang YM, Hsu YJ, Liu YJ, Chen HM, Yokoyama KK, Tsai KC, Yeh HH, Chen YR, Yang MT, Yang CY, Yang WC.

Oncogene. 2017 Sep 28;36(39):5484-5496. doi: 10.1038/onc.2017.156. Epub 2017 May 22.

PMID:
28534513
10.

Characterizing the structure-function relationship reveals the mode of action of a novel antimicrobial peptide, P1, from jumper ant Myrmecia pilosula.

Tseng TS, Tsai KC, Chen C.

Mol Biosyst. 2017 Jun 1;13(6):1193-1201. doi: 10.1039/c6mb00810k. Epub 2017 May 4.

PMID:
28470277
11.

Sarkosyl-Induced Helical Structure of an Antimicrobial Peptide GW-Q6 Plays an Essential Role in the Binding of Surface Receptor OprI in Pseudomonas aeruginosa.

Tseng TS, Wang SH, Chang TW, Wei HM, Wang YJ, Tsai KC, Liao YD, Chen C.

PLoS One. 2016 Oct 11;11(10):e0164597. doi: 10.1371/journal.pone.0164597. eCollection 2016.

12.

Predicting Ligand Binding Sites on Protein Surfaces by 3-Dimensional Probability Density Distributions of Interacting Atoms.

Jian JW, Elumalai P, Pitti T, Wu CY, Tsai KC, Chang JY, Peng HP, Yang AS.

PLoS One. 2016 Aug 11;11(8):e0160315. doi: 10.1371/journal.pone.0160315. eCollection 2016.

13.

Discovery of a potent cyclooxygenase-2 inhibitor, S4, through docking-based pharmacophore screening, in vivo and in vitro estimations.

Tseng TS, Chuang SM, Hsiao NW, Chen YW, Lee YC, Lin CC, Huang C, Tsai KC.

Mol Biosyst. 2016 Jul 19;12(8):2541-51. doi: 10.1039/c6mb00229c.

PMID:
27265567
14.

Peramivir Phosphonate Derivatives as Influenza Neuraminidase Inhibitors.

Wang PC, Fang JM, Tsai KC, Wang SY, Huang WI, Tseng YC, Cheng YS, Cheng TJ, Wong CH.

J Med Chem. 2016 Jun 9;59(11):5297-310. doi: 10.1021/acs.jmedchem.6b00029. Epub 2016 May 24.

PMID:
27167096
15.

Identifying N-linked glycan moiety and motifs in the cysteine-rich domain critical for N-glycosylation and intracellular trafficking of SR-AI and MARCO.

Tsay HJ, Huang YC, Chen YJ, Lee YH, Hsu SM, Tsai KC, Yang CN, Huang FL, Shie FS, Lee LC, Shiao YJ.

J Biomed Sci. 2016 Feb 18;23:27. doi: 10.1186/s12929-016-0244-5.

16.

Engineering a nanopore with co-chaperonin function.

Ho CW, Van Meervelt V, Tsai KC, De Temmerman PJ, Mast J, Maglia G.

Sci Adv. 2015 Dec 11;1(11):e1500905. doi: 10.1126/sciadv.1500905. eCollection 2015 Dec.

17.

Comparative study between 3D-QSAR and Docking-Based Pharmacophore models for potent Plasomodium falciparum dihydroorotate dehydrogenase inhibitors.

Tseng TS, Lee YC, Hsiao NW, Liu YR, Tsai KC.

Bioorg Med Chem Lett. 2016 Jan 15;26(2):265-271. doi: 10.1016/j.bmcl.2015.12.043. Epub 2015 Dec 12.

PMID:
26707392
18.

Discovery of novel FFA4 (GPR120) receptor agonists with β-arrestin2-biased characteristics.

Li A, Yang D, Zhu M, Tsai KC, Xiao KH, Yu X, Sun J, Du L.

Future Med Chem. 2015;7(18):2429-37. doi: 10.4155/fmc.15.160. Epub 2015 Dec 14.

PMID:
26653412
19.

Differential inhibition of CYP1-catalyzed regioselective hydroxylation of estradiol by berberine and its oxidative metabolites.

Chang YP, Huang CC, Shen CC, Tsai KC, Ueng YF.

Drug Metab Pharmacokinet. 2015 Oct;30(5):374-83. doi: 10.1016/j.dmpk.2015.08.006. Epub 2015 Aug 28.

PMID:
26403084
20.

Discovery of Potent Cysteine-Containing Dipeptide Inhibitors against Tyrosinase: A Comprehensive Investigation of 20 × 20 Dipeptides in Inhibiting Dopachrome Formation.

Tseng TS, Tsai KC, Chen WC, Wang YT, Lee YC, Lu CK, Don MJ, Chang CY, Lee CH, Lin HH, Hsu HJ, Hsiao NW.

J Agric Food Chem. 2015 Jul 15;63(27):6181-8. doi: 10.1021/acs.jafc.5b01026. Epub 2015 Jun 26.

PMID:
26083974

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