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1.

Light-Regulation of Tryptophan Synthase by Combining Protein Design and Enzymology.

Kneuttinger AC, Zwisele S, Straub K, Bruckmann A, Busch F, Kinateder T, Gaim B, Wysocki VH, Merkl R, Sterner R.

Int J Mol Sci. 2019 Oct 15;20(20). pii: E5106. doi: 10.3390/ijms20205106.

2.

Library Selection with a Randomized Repertoire of (βα)8-Barrel Enzymes Results in Unexpected Induction of Gene Expression.

Rohweder B, Lehmann G, Eichner N, Polen T, Rajendran C, Ruperti F, Linde M, Treiber T, Jung O, Dettmer K, Meister G, Bott M, Gronwald W, Sterner R.

Biochemistry. 2019 Oct 15;58(41):4207-4217. doi: 10.1021/acs.biochem.9b00579. Epub 2019 Oct 7.

PMID:
31557000
3.

Light Regulation of Enzyme Allostery through Photo-responsive Unnatural Amino Acids.

Kneuttinger AC, Straub K, Bittner P, Simeth NA, Bruckmann A, Busch F, Rajendran C, Hupfeld E, Wysocki VH, Horinek D, König B, Merkl R, Sterner R.

Cell Chem Biol. 2019 Sep 4. pii: S2451-9456(19)30271-5. doi: 10.1016/j.chembiol.2019.08.006. [Epub ahead of print]

PMID:
31495713
4.

Prediction of quaternary structure by analysis of hot spot residues in protein-protein interfaces: the case of anthranilate phosphoribosyltransferases.

Schlee S, Straub K, Schwab T, Kinateder T, Merkl R, Sterner R.

Proteins. 2019 Oct;87(10):815-825. doi: 10.1002/prot.25744. Epub 2019 Jun 10.

PMID:
31134642
5.

Mapping the Allosteric Communication Network of Aminodeoxychorismate Synthase.

Semmelmann F, Straub K, Nazet J, Rajendran C, Merkl R, Sterner R.

J Mol Biol. 2019 Jul 12;431(15):2718-2728. doi: 10.1016/j.jmb.2019.05.021. Epub 2019 May 21.

PMID:
31121180
6.

A Fold-Independent Interface Residue Is Crucial for Complex Formation and Allosteric Signaling in Class I Glutamine Amidotransferases.

Semmelmann F, Hupfeld E, Heizinger L, Merkl R, Sterner R.

Biochemistry. 2019 Jun 4;58(22):2584-2588. doi: 10.1021/acs.biochem.9b00286. Epub 2019 May 23.

PMID:
31117390
7.

Generation of a Stand-Alone Tryptophan Synthase α-Subunit by Mimicking an Evolutionary Blueprint.

Schupfner M, Busch F, Wysocki VH, Sterner R.

Chembiochem. 2019 Nov 4;20(21):2747-2751. doi: 10.1002/cbic.201900323. Epub 2019 Aug 28.

PMID:
31090986
8.

Functional characterisation of two Δ12-desaturases demonstrates targeted production of linoleic acid as pheromone precursor in Nasonia.

Semmelmann F, Kabeya N, Malcicka M, Bruckmann A, Broschwitz B, Straub K, Merkl R, Monroig O, Sterner R, Ruther J, Ellers J.

J Exp Biol. 2019 May 16;222(Pt 10). pii: jeb201038. doi: 10.1242/jeb.201038.

9.

Tale of Two Storms: Impact of Extreme Rain Events on the Biogeochemistry of Lake Superior.

Cooney EM, McKinney P, Sterner R, Small GE, Minor EC.

J Geophys Res Biogeosci. 2018;123(5):1719-1731. doi: 10.1029/2017JG004216.

10.
11.

Evolutionary Morphing of Tryptophan Synthase: Functional Mechanisms for the Enzymatic Channeling of Indole.

Fleming JR, Schupfner M, Busch F, Baslé A, Ehrmann A, Sterner R, Mayans O.

J Mol Biol. 2018 Dec 7;430(24):5066-5079. doi: 10.1016/j.jmb.2018.10.013. Epub 2018 Oct 25.

PMID:
30367843
12.

Artificial Light Regulation of an Allosteric Bienzyme Complex by a Photosensitive Ligand.

Kneuttinger AC, Winter M, Simeth NA, Heyn K, Merkl R, König B, Sterner R.

Chembiochem. 2018 May 29. doi: 10.1002/cbic.201800219. [Epub ahead of print]

PMID:
29808949
13.

Hexamerization of Geranylgeranylglyceryl Phosphate Synthase Ensures Structural Integrity and Catalytic Activity at High Temperatures.

Linde M, Heyn K, Merkl R, Sterner R, Babinger P.

Biochemistry. 2018 Apr 24;57(16):2335-2348. doi: 10.1021/acs.biochem.7b01284. Epub 2018 Apr 11.

PMID:
29600842
14.

Relationship of Catalysis and Active Site Loop Dynamics in the (βα)8-Barrel Enzyme Indole-3-glycerol Phosphate Synthase.

Schlee S, Klein T, Schumacher M, Nazet J, Merkl R, Steinhoff HJ, Sterner R.

Biochemistry. 2018 Jun 12;57(23):3265-3277. doi: 10.1021/acs.biochem.8b00167. Epub 2018 Mar 8.

PMID:
29498826
15.

Standardized cloning vectors for protein production and generation of large gene libraries in Escherichia coli.

Rohweder B, Semmelmann F, Endres C, Sterner R.

Biotechniques. 2018 Jan 1;64(1):24-26. doi: 10.2144/000114628.

16.

Library Generation and Auxotrophic Selection Assays in Escherichia coli and Thermus thermophilus.

Claren J, Schwab T, Sterner R.

Methods Mol Biol. 2018;1685:333-345. doi: 10.1007/978-1-4939-7366-8_20.

PMID:
29086319
17.

Photochromic coenzyme Q derivatives: switching redox potentials with light.

Simeth NA, Kneuttinger AC, Sterner R, König B.

Chem Sci. 2017 Sep 1;8(9):6474-6483. doi: 10.1039/c7sc00781g. Epub 2017 Jul 20.

18.

Evolutionary diversification of protein-protein interactions by interface add-ons.

Plach MG, Semmelmann F, Busch F, Busch M, Heizinger L, Wysocki VH, Merkl R, Sterner R.

Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):E8333-E8342. doi: 10.1073/pnas.1707335114. Epub 2017 Sep 18.

19.

Rosetta:MSF: a modular framework for multi-state computational protein design.

Löffler P, Schmitz S, Hupfeld E, Sterner R, Merkl R.

PLoS Comput Biol. 2017 Jun 12;13(6):e1005600. doi: 10.1371/journal.pcbi.1005600. eCollection 2017 Jun.

20.

Diversity of bacteria and archaea from two shallow marine hydrothermal vents from Vulcano Island.

Antranikian G, Suleiman M, Schäfers C, Adams MWW, Bartolucci S, Blamey JM, Birkeland NK, Bonch-Osmolovskaya E, da Costa MS, Cowan D, Danson M, Forterre P, Kelly R, Ishino Y, Littlechild J, Moracci M, Noll K, Oshima T, Robb F, Rossi M, Santos H, Schönheit P, Sterner R, Thauer R, Thomm M, Wiegel J, Stetter KO.

Extremophiles. 2017 Jul;21(4):733-742. doi: 10.1007/s00792-017-0938-y. Epub 2017 May 10.

PMID:
28493148

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