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Items: 1 to 20 of 93


In silico prediction of Heterocyclic Aromatic Amines metabolism susceptible to form DNA adducts in humans.

Delannée V, Langouët S, Siegel A, Théret N.

Toxicol Lett. 2018 Oct 10;300:18-30. doi: 10.1016/j.toxlet.2018.10.011. [Epub ahead of print]


Long term exposure to environmental concentrations of diesel exhaust particles does not impact the phenotype of human bronchial epithelial cells.

Savary CC, Bellamri N, Morzadec C, Langouët S, Lecureur V, Vernhet L.

Toxicol In Vitro. 2018 Oct;52:154-160. doi: 10.1016/j.tiv.2018.06.014. Epub 2018 Jun 19.


Proteomic screening identifies the zonula occludens protein ZO-1 as a new partner for ADAM12 in invadopodia-like structures.

Dekky B, Ruff M, Bonnier D, Legagneux V, Théret N.

Oncotarget. 2018 Apr 20;9(30):21366-21382. doi: 10.18632/oncotarget.25106. eCollection 2018 Apr 20.


Molecular and tissue alterations of collagens in fibrosis.

Ricard-Blum S, Baffet G, Théret N.

Matrix Biol. 2018 Aug;68-69:122-149. doi: 10.1016/j.matbio.2018.02.004. Epub 2018 Feb 17. Review.


Determination of extracellular matrix collagen fibril architectures and pathological remodeling by polarization dependent second harmonic microscopy.

Rouède D, Schaub E, Bellanger JJ, Ezan F, Scimeca JC, Baffet G, Tiaho F.

Sci Rep. 2017 Sep 22;7(1):12197. doi: 10.1038/s41598-017-12398-0.


A modeling approach to evaluate the balance between bioactivation and detoxification of MeIQx in human hepatocytes.

Delannée V, Langouët S, Théret N, Siegel A.

PeerJ. 2017 Sep 1;5:e3703. doi: 10.7717/peerj.3703. eCollection 2017.


[1-9-NαC]-crourorb A1 isolated from Croton urucurana latex induces G2/M cell cycle arrest and apoptosis in human hepatocarcinoma cells.

de Matos Cândido-Bacani P, Ezan F, de Oliveira Figueiredo P, Matos MFC, Rodrigues Garcez F, Silva Garcez W, Baffet G.

Toxicol Lett. 2017 May 5;273:44-54. doi: 10.1016/j.toxlet.2017.03.020. Epub 2017 Mar 23.


Metabolism of the Tobacco Carcinogen 2-Amino-9H-pyrido[2,3-b]indole (AαC) in Primary Human Hepatocytes.

Bellamri M, Le Hegarat L, Turesky RJ, Langouët S.

Chem Res Toxicol. 2017 Feb 20;30(2):657-668. doi: 10.1021/acs.chemrestox.6b00394. Epub 2016 Dec 15.


Human T lymphocytes bioactivate heterocyclic aromatic amines by forming DNA adducts.

Bellamri M, Le Hegarat L, Vernhet L, Baffet G, Turesky RJ, Langouët S.

Environ Mol Mutagen. 2016 Dec;57(9):656-667. doi: 10.1002/em.22059. Epub 2016 Nov 1.


Geometric analysis of pathways dynamics: Application to versatility of TGF-β receptors.

Samal SS, Naldi A, Grigoriev D, Weber A, Théret N, Radulescu O.

Biosystems. 2016 Nov;149:3-14. doi: 10.1016/j.biosystems.2016.07.004. Epub 2016 Jul 21.


TGFβ Signaling Intersects with CD103 Integrin Signaling to Promote T-Lymphocyte Accumulation and Antitumor Activity in the Lung Tumor Microenvironment.

Boutet M, Gauthier L, Leclerc M, Gros G, de Montpreville V, Théret N, Donnadieu E, Mami-Chouaib F.

Cancer Res. 2016 Apr 1;76(7):1757-69. doi: 10.1158/0008-5472.CAN-15-1545. Epub 2016 Feb 26.


In silico characterization of the interaction between LSKL peptide, a LAP-TGF-beta derived peptide, and ADAMTS1.

Laurent MA, Bonnier D, Théret N, Tufféry P, Moroy G.

Comput Biol Chem. 2016 Apr;61:155-61. doi: 10.1016/j.compbiolchem.2016.01.012. Epub 2016 Jan 31.


Chlordecone potentiates hepatic fibrosis in chronic liver injury induced by carbon tetrachloride in mice.

Tabet E, Genet V, Tiaho F, Lucas-Clerc C, Gelu-Simeon M, Piquet-Pellorce C, Samson M.

Toxicol Lett. 2016 Jul 25;255:1-10. doi: 10.1016/j.toxlet.2016.02.005. Epub 2016 Feb 4.


The probiotic Propionibacterium freudenreichii as a new adjuvant for TRAIL-based therapy in colorectal cancer.

Cousin FJ, Jouan-Lanhouet S, Théret N, Brenner C, Jouan E, Le Moigne-Muller G, Dimanche-Boitrel MT, Jan G.

Oncotarget. 2016 Feb 9;7(6):7161-78. doi: 10.18632/oncotarget.6881.


The Disintegrin and Metalloprotease ADAM12 Is Associated with TGF-β-Induced Epithelial to Mesenchymal Transition.

Ruff M, Leyme A, Le Cann F, Bonnier D, Le Seyec J, Chesnel F, Fattet L, Rimokh R, Baffet G, Théret N.

PLoS One. 2015 Sep 25;10(9):e0139179. doi: 10.1371/journal.pone.0139179. eCollection 2015.


Increasing 3D Matrix Rigidity Strengthens Proliferation and Spheroid Development of Human Liver Cells in a Constant Growth Factor Environment.

Bomo J, Ezan F, Tiaho F, Bellamri M, Langouët S, Theret N, Baffet G.

J Cell Biochem. 2016 Mar;117(3):708-20. doi: 10.1002/jcb.25356. Epub 2015 Sep 8.


Linear least square (LLS) method for pixel-resolution analysis of polarization dependent SHG images of collagen fibrils.

Rouède D, Bellanger JJ, Bomo J, Baffet G, Tiaho F.

Opt Express. 2015 May 18;23(10):13309-19. doi: 10.1364/OE.23.013309.


2-Amino-9H-pyrido[2,3-b]indole (AαC) Adducts and Thiol Oxidation of Serum Albumin as Potential Biomarkers of Tobacco Smoke.

Pathak KV, Bellamri M, Wang Y, Langouët S, Turesky RJ.

J Biol Chem. 2015 Jun 26;290(26):16304-18. doi: 10.1074/jbc.M115.646539. Epub 2015 May 7.


Mass Spectrometric Characterization of Human Serum Albumin Adducts Formed with N-Oxidized Metabolites of 2-Amino-1-methylphenylimidazo[4,5-b]pyridine in Human Plasma and Hepatocytes.

Wang Y, Peng L, Bellamri M, Langouët S, Turesky RJ.

Chem Res Toxicol. 2015 May 18;28(5):1045-59. doi: 10.1021/acs.chemrestox.5b00075. Epub 2015 Apr 10.


Structural origin of the drastic modification of second harmonic generation intensity pattern occurring in tail muscles of climax stages xenopus tadpoles.

Recher G, Coumailleau P, Rouède D, Tiaho F.

J Struct Biol. 2015 Apr;190(1):1-10. doi: 10.1016/j.jsb.2015.03.003. Epub 2015 Mar 11.

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