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Items: 1 to 20 of 69

1.

Tumour-elicited neutrophils engage mitochondrial metabolism to circumvent nutrient limitations and maintain immune suppression.

Rice CM, Davies LC, Subleski JJ, Maio N, Gonzalez-Cotto M, Andrews C, Patel NL, Palmieri EM, Weiss JM, Lee JM, Annunziata CM, Rouault TA, Durum SK, McVicar DW.

Nat Commun. 2018 Nov 30;9(1):5099. doi: 10.1038/s41467-018-07505-2.

2.

Diversity and environmental adaptation of phagocytic cell metabolism.

Davies LC, Rice CM, McVicar DW, Weiss JM.

J Leukoc Biol. 2019 Jan;105(1):37-48. doi: 10.1002/JLB.4RI0518-195R. Epub 2018 Sep 14. Review.

3.

Understanding the tumour micro-environment communication network from an NOS2/COX2 perspective.

Basudhar D, Bharadwaj G, Somasundaram V, Cheng RYS, Ridnour LA, Fujita M, Lockett SJ, Anderson SK, McVicar DW, Wink DA.

Br J Pharmacol. 2019 Jan;176(2):155-176. doi: 10.1111/bph.14488. Epub 2018 Nov 6. Review.

PMID:
30152521
4.

Itaconic acid mediates crosstalk between macrophage metabolism and peritoneal tumors.

Weiss JM, Davies LC, Karwan M, Ileva L, Ozaki MK, Cheng RY, Ridnour LA, Annunziata CM, Wink DA, McVicar DW.

J Clin Invest. 2018 Aug 31;128(9):3794-3805. doi: 10.1172/JCI99169. Epub 2018 Jul 30.

5.

TLR-activated repression of Fe-S cluster biogenesis drives a metabolic shift and alters histone and tubulin acetylation.

Tong WH, Maio N, Zhang DL, Palmieri EM, Ollivierre H, Ghosh MC, McVicar DW, Rouault TA.

Blood Adv. 2018 May 22;2(10):1146-1156. doi: 10.1182/bloodadvances.2018015669.

6.

Molecular Mechanisms of Nitric Oxide in Cancer Progression, Signal Transduction, and Metabolism.

Somasundaram V, Basudhar D, Bharadwaj G, No JH, Ridnour LA, Cheng RYS, Fujita M, Thomas DD, Anderson SK, McVicar DW, Wink DA.

Antioxid Redox Signal. 2019 Mar 10;30(8):1124-1143. doi: 10.1089/ars.2018.7527. Epub 2018 May 2.

PMID:
29634348
7.

Identification of an elaborate NK-specific system regulating HLA-C expression.

Li H, Ivarsson MA, Walker-Sperling VE, Subleski J, Johnson JK, Wright PW, Carrington M, Björkström NK, McVicar DW, Anderson SK.

PLoS Genet. 2018 Jan 12;14(1):e1007163. doi: 10.1371/journal.pgen.1007163. eCollection 2018 Jan.

8.

Peritoneal tissue-resident macrophages are metabolically poised to engage microbes using tissue-niche fuels.

Davies LC, Rice CM, Palmieri EM, Taylor PR, Kuhns DB, McVicar DW.

Nat Commun. 2017 Dec 12;8(1):2074. doi: 10.1038/s41467-017-02092-0.

9.

Coexpression of NOS2 and COX2 accelerates tumor growth and reduces survival in estrogen receptor-negative breast cancer.

Basudhar D, Glynn SA, Greer M, Somasundaram V, No JH, Scheiblin DA, Garrido P, Heinz WF, Ryan AE, Weiss JM, Cheng RYS, Ridnour LA, Lockett SJ, McVicar DW, Ambs S, Wink DA.

Proc Natl Acad Sci U S A. 2017 Dec 5;114(49):13030-13035. doi: 10.1073/pnas.1709119114. Epub 2017 Oct 27.

10.

Pharmacologic or Genetic Targeting of Glutamine Synthetase Skews Macrophages toward an M1-like Phenotype and Inhibits Tumor Metastasis.

Palmieri EM, Menga A, Martín-Pérez R, Quinto A, Riera-Domingo C, De Tullio G, Hooper DC, Lamers WH, Ghesquière B, McVicar DW, Guarini A, Mazzone M, Castegna A.

Cell Rep. 2017 Aug 15;20(7):1654-1666. doi: 10.1016/j.celrep.2017.07.054.

11.

MHC-I peptides get out of the groove and enable a novel mechanism of HIV-1 escape.

Pymm P, Illing PT, Ramarathinam SH, O'Connor GM, Hughes VA, Hitchen C, Price DA, Ho BK, McVicar DW, Brooks AG, Purcell AW, Rossjohn J, Vivian JP.

Nat Struct Mol Biol. 2017 Apr;24(4):387-394. doi: 10.1038/nsmb.3381. Epub 2017 Feb 20.

PMID:
28218747
12.

Inducible Nitric Oxide Synthase in the Carcinogenesis of Gastrointestinal Cancers.

de Oliveira GA, Cheng RYS, Ridnour LA, Basudhar D, Somasundaram V, McVicar DW, Monteiro HP, Wink DA.

Antioxid Redox Signal. 2017 Jun 20;26(18):1059-1077. doi: 10.1089/ars.2016.6850. Epub 2016 Oct 31. Review.

13.

CD164 identifies CD4+ T cells highly expressing genes associated with malignancy in Sézary syndrome: the Sézary signature genes, FCRL3, Tox, and miR-214.

Benoit BM, Jariwala N, O'Connor G, Oetjen LK, Whelan TM, Werth A, Troxel AB, Sicard H, Zhu L, Miller C, Takeshita J, McVicar DW, Kim BS, Rook AH, Wysocka M.

Arch Dermatol Res. 2017 Jan;309(1):11-19. doi: 10.1007/s00403-016-1698-8. Epub 2016 Oct 20.

14.

Autocrine IL-10 functions as a rheostat for M1 macrophage glycolytic commitment by tuning nitric oxide production.

Baseler WA, Davies LC, Quigley L, Ridnour LA, Weiss JM, Hussain SP, Wink DA, McVicar DW.

Redox Biol. 2016 Dec;10:12-23. doi: 10.1016/j.redox.2016.09.005. Epub 2016 Sep 16.

15.

Analysis of Ly49 gene transcripts in mature NK cells supports a role for the Pro1 element in gene activation, not gene expression.

McCullen MV, Li H, Cam M, Sen SK, McVicar DW, Anderson SK.

Genes Immun. 2016 Sep;17(6):349-57. doi: 10.1038/gene.2016.31. Epub 2016 Jul 28.

16.

Orally administered β-glucan attenuates the Th2 response in a model of airway hypersensitivity.

Burg AR, Quigley L, Jones AV, O'Connor GM, Boelte K, McVicar DW, Orr SJ.

Springerplus. 2016 Jun 21;5(1):815. doi: 10.1186/s40064-016-2501-1. eCollection 2016.

17.

Killer cell immunoglobulin-like receptor 3DL1 polymorphism defines distinct hierarchies of HLA class I recognition.

Saunders PM, Pymm P, Pietra G, Hughes VA, Hitchen C, O'Connor GM, Loiacono F, Widjaja J, Price DA, Falco M, Mingari MC, Moretta L, McVicar DW, Rossjohn J, Brooks AG, Vivian JP.

J Exp Med. 2016 May 2;213(5):791-807. doi: 10.1084/jem.20152023. Epub 2016 Apr 4.

18.

NAFLD causes selective CD4(+) T lymphocyte loss and promotes hepatocarcinogenesis.

Ma C, Kesarwala AH, Eggert T, Medina-Echeverz J, Kleiner DE, Jin P, Stroncek DF, Terabe M, Kapoor V, ElGindi M, Han M, Thornton AM, Zhang H, Egger M, Luo J, Felsher DW, McVicar DW, Weber A, Heikenwalder M, Greten TF.

Nature. 2016 Mar 10;531(7593):253-7. doi: 10.1038/nature16969. Epub 2016 Mar 2.

19.

Bortezomib Improves Adoptive T-cell Therapy by Sensitizing Cancer Cells to FasL Cytotoxicity.

Shanker A, Pellom ST Jr, Dudimah DF, Thounaojam MC, de Kluyver RL, Brooks AD, Yagita H, McVicar DW, Murphy WJ, Longo DL, Sayers TJ.

Cancer Res. 2015 Dec 15;75(24):5260-72. doi: 10.1158/0008-5472.CAN-15-0794. Epub 2015 Oct 22.

20.

Signaling and stress: The redox landscape in NOS2 biology.

Thomas DD, Heinecke JL, Ridnour LA, Cheng RY, Kesarwala AH, Switzer CH, McVicar DW, Roberts DD, Glynn S, Fukuto JM, Wink DA, Miranda KM.

Free Radic Biol Med. 2015 Oct;87:204-25. doi: 10.1016/j.freeradbiomed.2015.06.002. Epub 2015 Jun 24. Review.

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