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Items: 1 to 20 of 32


Alternative Mode of E-Site tRNA Binding in the Presence of a Downstream mRNA Stem Loop at the Entrance Channel.

Zhang Y, Hong S, Ruangprasert A, Skiniotis G, Dunham CM.

Structure. 2018 Mar 6;26(3):437-445.e3. doi: 10.1016/j.str.2018.01.013. Epub 2018 Feb 15.


Genome mining: Digging the tunnel for chemical space.

Nguyen HA, Dunham CM.

Nat Chem Biol. 2017 Sep 19;13(10):1061-1062. doi: 10.1038/nchembio.2480. No abstract available.


The structure and function of Mycobacterium tuberculosis MazF-mt6 toxin provide insights into conserved features of MazF endonucleases.

Hoffer ED, Miles SJ, Dunham CM.

J Biol Chem. 2017 May 12;292(19):7718-7726. doi: 10.1074/jbc.M117.779306. Epub 2017 Mar 15.


Importance of the E. coli DinJ antitoxin carboxy terminus for toxin suppression and regulated proteolysis.

Ruangprasert A, Maehigashi T, Miles SJ, Dunham CM.

Mol Microbiol. 2017 Apr;104(1):65-77. doi: 10.1111/mmi.13641. Epub 2017 Feb 28.


Uniformity of Peptide Release Is Maintained by Methylation of Release Factors.

Pierson WE, Hoffer ED, Keedy HE, Simms CL, Dunham CM, Zaher HS.

Cell Rep. 2016 Sep 27;17(1):11-18. doi: 10.1016/j.celrep.2016.08.085.


Mechanism of endonuclease cleavage by the HigB toxin.

Schureck MA, Repack A, Miles SJ, Marquez J, Dunham CM.

Nucleic Acids Res. 2016 Sep 19;44(16):7944-53. doi: 10.1093/nar/gkw598. Epub 2016 Jul 4.


mRNA bound to the 30S subunit is a HigB toxin substrate.

Schureck MA, Maehigashi T, Miles SJ, Marquez J, Dunham CM.

RNA. 2016 Aug;22(8):1261-70. doi: 10.1261/rna.056218.116. Epub 2016 Jun 15.


Defining the mRNA recognition signature of a bacterial toxin protein.

Schureck MA, Dunkle JA, Maehigashi T, Miles SJ, Dunham CM.

Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):13862-7. doi: 10.1073/pnas.1512959112. Epub 2015 Oct 27.


Molecular basis of ribosome recognition and mRNA hydrolysis by the E. coli YafQ toxin.

Maehigashi T, Ruangprasert A, Miles SJ, Dunham CM.

Nucleic Acids Res. 2015 Sep 18;43(16):8002-12. doi: 10.1093/nar/gkv791. Epub 2015 Aug 10.


Growth-regulating Mycobacterium tuberculosis VapC-mt4 toxin is an isoacceptor-specific tRNase.

Cruz JW, Sharp JD, Hoffer ED, Maehigashi T, Vvedenskaya IO, Konkimalla A, Husson RN, Nickels BE, Dunham CM, Woychik NA.

Nat Commun. 2015 Jul 9;6:7480. doi: 10.1038/ncomms8480.


Mechanisms of mRNA frame maintenance and its subversion during translation of the genetic code.

Dunkle JA, Dunham CM.

Biochimie. 2015 Jul;114:90-6. doi: 10.1016/j.biochi.2015.02.007. Epub 2015 Feb 21. Review.


Structural insights into translational recoding by frameshift suppressor tRNASufJ.

Fagan CE, Maehigashi T, Dunkle JA, Miles SJ, Dunham CM.

RNA. 2014 Dec;20(12):1944-54. doi: 10.1261/rna.046953.114. Epub 2014 Oct 28.


Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops.

Maehigashi T, Dunkle JA, Miles SJ, Dunham CM.

Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):12740-5. doi: 10.1073/pnas.1409436111. Epub 2014 Aug 15.


Mechanisms of toxin inhibition and transcriptional repression by Escherichia coli DinJ-YafQ.

Ruangprasert A, Maehigashi T, Miles SJ, Giridharan N, Liu JX, Dunham CM.

J Biol Chem. 2014 Jul 25;289(30):20559-69. doi: 10.1074/jbc.M114.573006. Epub 2014 Jun 4.


Bacterial warfare again targets the ribosome.

Schureck MA, Dunham CM.

Structure. 2014 May 6;22(5):661-2. doi: 10.1016/j.str.2014.04.007.


Molecular recognition and modification of the 30S ribosome by the aminoglycoside-resistance methyltransferase NpmA.

Dunkle JA, Vinal K, Desai PM, Zelinskaya N, Savic M, West DM, Conn GL, Dunham CM.

Proc Natl Acad Sci U S A. 2014 Apr 29;111(17):6275-80. doi: 10.1073/pnas.1402789111. Epub 2014 Apr 9.


Structure of the Proteus vulgaris HigB-(HigA)2-HigB toxin-antitoxin complex.

Schureck MA, Maehigashi T, Miles SJ, Marquez J, Cho SE, Erdman R, Dunham CM.

J Biol Chem. 2014 Jan 10;289(2):1060-70. doi: 10.1074/jbc.M113.512095. Epub 2013 Nov 20.


Stress granules form in Brachionus manjavacas (Rotifera) in response to a variety of stressors.

Jones BL, VanLoozen J, Kim MH, Miles SJ, Dunham CM, Williams LD, Snell TW.

Comp Biochem Physiol A Mol Integr Physiol. 2013 Oct;166(2):375-84. doi: 10.1016/j.cbpa.2013.07.009. Epub 2013 Jul 12.


Reorganization of an intersubunit bridge induced by disparate 16S ribosomal ambiguity mutations mimics an EF-Tu-bound state.

Fagan CE, Dunkle JA, Maehigashi T, Dang MN, Devaraj A, Miles SJ, Qin D, Fredrick K, Dunham CM.

Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9716-21. doi: 10.1073/pnas.1301585110. Epub 2013 Apr 29.


Structure of the basal components of a bacterial transporter.

Meisner J, Maehigashi T, André I, Dunham CM, Moran CP Jr.

Proc Natl Acad Sci U S A. 2012 Apr 3;109(14):5446-51. doi: 10.1073/pnas.1120113109. Epub 2012 Mar 19.

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