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1.

Directly Reprogrammed Human Neurons Retain Aging-Associated Transcriptomic Signatures and Reveal Age-Related Nucleocytoplasmic Defects.

Mertens J, Paquola ACM, Ku M, Hatch E, Böhnke L, Ladjevardi S, McGrath S, Campbell B, Lee H, Herdy JR, Gonçalves JT, Toda T, Kim Y, Winkler J, Yao J, Hetzer MW, Gage FH.

Cell Stem Cell. 2015 Dec 3;17(6):705-718. doi: 10.1016/j.stem.2015.09.001. Epub 2015 Oct 8.

2.

Neuronal medium that supports basic synaptic functions and activity of human neurons in vitro.

Bardy C, van den Hurk M, Eames T, Marchand C, Hernandez RV, Kellogg M, Gorris M, Galet B, Palomares V, Brown J, Bang AG, Mertens J, Böhnke L, Boyer L, Simon S, Gage FH.

Proc Natl Acad Sci U S A. 2015 May 19;112(20):E2725-34. doi: 10.1073/pnas.1504393112. Epub 2015 Apr 13. Erratum in: Proc Natl Acad Sci U S A. 2015 Jun 23;112(25):E3312.

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