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Items: 1 to 20 of 61


A Dithiol Compound Binds to the Zinc Finger Protein TRAF6 and Suppresses Its Ubiquitination.

Koga R, Radwan MO, Ejima T, Kanemaru Y, Tateishi H, Ali TFS, Ciftci HI, Shibata Y, Taguchi Y, Inoue JI, Otsuka M, Fujita M.

ChemMedChem. 2017 Dec 7;12(23):1935-1941. doi: 10.1002/cmdc.201700399. Epub 2017 Oct 4.


Cinchonine induces apoptosis of HeLa and A549 cells through targeting TRAF6.

Qi Y, Pradipta AR, Li M, Zhao X, Lu L, Fu X, Wei J, Hsung RP, Tanaka K, Zhou L.

J Exp Clin Cancer Res. 2017 Feb 23;36(1):35. doi: 10.1186/s13046-017-0502-8.


An ensemble micro neural network approach for elucidating interactions between zinc finger proteins and their target DNA.

Dutta S, Madan S, Parikh H, Sundar D.

BMC Genomics. 2016 Dec 22;17(Suppl 13):1033. doi: 10.1186/s12864-016-3323-9.


Physical Interaction of Human Yin Yang 1 Protein with DNA.

Figiel M, Górecki A.

Crit Rev Oncog. 2017;22(1-2):75-97. doi: 10.1615/CritRevOncog.2017020976.


B Cell Receptor Activation Predominantly Regulates AKT-mTORC1/2 Substrates Functionally Related to RNA Processing.

Mohammad DK, Ali RH, Turunen JJ, Nore BF, Smith CI.

PLoS One. 2016 Aug 3;11(8):e0160255. doi: 10.1371/journal.pone.0160255. eCollection 2016.


Metal binding mediated conformational change of XPA protein:a potential cytotoxic mechanism of nickel in the nucleotide excision repair.

Hu J, Hu Z, Zhang Y, Gou X, Mu Y, Wang L, Xie XQ.

J Mol Model. 2016 Jul;22(7):156. doi: 10.1007/s00894-016-3017-x. Epub 2016 Jun 16.


Structural basis for histone H2B deubiquitination by the SAGA DUB module.

Morgan MT, Haj-Yahya M, Ringel AE, Bandi P, Brik A, Wolberger C.

Science. 2016 Feb 12;351(6274):725-8. doi: 10.1126/science.aac5681.


Transposable Elements, Polydactyl Proteins, and the Genesis of Human-Specific Transcription Networks.

Trono D.

Cold Spring Harb Symp Quant Biol. 2015;80:281-8. doi: 10.1101/sqb.2015.80.027573. Epub 2016 Jan 13. Review.


A theoretical investigation of DNA dynamics and desolvation kinetics for zinc finger proteinZif268.

Dutta S, Agrawal Y, Mishra A, Dhanjal JK, Sundar D.

BMC Genomics. 2015;16 Suppl 12:S5. doi: 10.1186/1471-2164-16-S12-S5. Epub 2015 Dec 9.


Novel fused tetrathiocines as antivirals that target the nucleocapsid zinc finger containing protein of the feline immunodeficiency virus (FIV) as a model of HIV infection.

Asquith CR, Meli ML, Konstantinova LS, Laitinen T, Poso A, Rakitin OA, Hofmann-Lehmann R, Allenspach K, Hilton ST.

Bioorg Med Chem Lett. 2015 Mar 15;25(6):1352-5. doi: 10.1016/j.bmcl.2014.12.047. Epub 2014 Dec 20.


Towards understanding the molecular recognition process in prokaryotic zinc-finger domain.

Russo L, Palmieri M, Caso JV, D'Abrosca G, Diana D, Malgieri G, Baglivo I, Isernia C, Pedone PV, Fattorusso R.

Eur J Med Chem. 2015 Feb 16;91:100-8. doi: 10.1016/j.ejmech.2014.09.040. Epub 2014 Sep 16.


Mode and specificity of binding of the small molecule GANT61 to GLI determines inhibition of GLI-DNA binding.

Agyeman A, Jha BK, Mazumdar T, Houghton JA.

Oncotarget. 2014 Jun 30;5(12):4492-503.


Structural analysis of viral infectivity factor of HIV type 1 and its interaction with A3G, EloC and EloB.

da Costa KS, Leal E, dos Santos AM, Lima e Lima AH, Alves CN, Lameira J.

PLoS One. 2014 Feb 26;9(2):e89116. doi: 10.1371/journal.pone.0089116. eCollection 2014.


Structural characterization of interactions between the double-stranded RNA-binding zinc finger protein JAZ and nucleic acids.

Burge RG, Martinez-Yamout MA, Dyson HJ, Wright PE.

Biochemistry. 2014 Mar 11;53(9):1495-510. doi: 10.1021/bi401675h. Epub 2014 Feb 27.


Docking ligands into flexible and solvated macromolecules. 6. Development and application to the docking of HDACs and other zinc metalloenzymes inhibitors.

Pottel J, Therrien E, Gleason JL, Moitessier N.

J Chem Inf Model. 2014 Jan 27;54(1):254-65. doi: 10.1021/ci400550m. Epub 2014 Jan 8.


A phylogenetic study of SPBP and RAI1: evolutionary conservation of chromatin binding modules.

Darvekar S, Rekdal C, Johansen T, Sjøttem E.

PLoS One. 2013 Oct 18;8(10):e78907. doi: 10.1371/journal.pone.0078907. eCollection 2013.


An in silico appraisal of azoic and disulphide derivatives for anticancer activity against HPV E6 oncoprotein to medicate cervical cancer.

Choudhury AD, Choudhury MD, Chetia P, Chowdhury A, Talukdar AD.

Comb Chem High Throughput Screen. 2014 Jan;17(1):38-46.


Targeted transgene insertion into the AAVS1 locus driven by baculoviral vector-mediated zinc finger nuclease expression in human-induced pluripotent stem cells.

Tay FC, Tan WK, Goh SL, Ramachandra CJ, Lau CH, Zhu H, Chen C, Du S, Phang RZ, Shahbazi M, Fan W, Wang S.

J Gene Med. 2013 Oct;15(10):384-95. doi: 10.1002/jgm.2745.


A structural analysis of DNA binding by myelin transcription factor 1 double zinc fingers.

Gamsjaeger R, O'Connell MR, Cubeddu L, Shepherd NE, Lowry JA, Kwan AH, Vandevenne M, Swanton MK, Matthews JM, Mackay JP.

J Biol Chem. 2013 Dec 6;288(49):35180-91. doi: 10.1074/jbc.M113.482075. Epub 2013 Oct 6.


A method for in silico identification of SNAIL/SLUG DNA binding potentials to the E-box sequence using molecular dynamics and evolutionary conserved amino acids.

Prokop JW, Liu Y, Milsted A, Peng H, Rauscher FJ 3rd.

J Mol Model. 2013 Sep;19(9):3463-9. doi: 10.1007/s00894-013-1876-y. Epub 2013 May 25.

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