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Items: 1 to 20 of 126


Increased levels of RECQ5 shift DNA repair from canonical to alternative pathways.

Olson HC, Davis L, Kiianitsa K, Khoo KJ, Liu Y, Knijnenburg TA, Maizels N.

Nucleic Acids Res. 2018 Oct 12;46(18):9496-9509. doi: 10.1093/nar/gky727.


Initiation of homologous recombination at DNA nicks.

Maizels N, Davis L.

Nucleic Acids Res. 2018 Aug 21;46(14):6962-6973. doi: 10.1093/nar/gky588.


Assaying Repair at DNA Nicks.

Davis L, Zhang Y, Maizels N.

Methods Enzymol. 2018;601:71-89. doi: 10.1016/bs.mie.2017.12.001. Epub 2018 Feb 1.


Two Distinct Pathways Support Gene Correction by Single-Stranded Donors at DNA Nicks.

Davis L, Maizels N.

Cell Rep. 2016 Nov 8;17(7):1872-1881. doi: 10.1016/j.celrep.2016.10.049.


The Werner syndrome RECQ helicase targets G4 DNA in human cells to modulate transcription.

Tang W, Robles AI, Beyer RP, Gray LT, Nguyen GH, Oshima J, Maizels N, Harris CC, Monnat RJ Jr.

Hum Mol Genet. 2016 May 15;25(10):2060-2069. Epub 2016 Mar 16.


Cell Cycle Regulates Nuclear Stability of AID and Determines the Cellular Response to AID.

Le Q, Maizels N.

PLoS Genet. 2015 Sep 10;11(9):e1005411. doi: 10.1371/journal.pgen.1005411. eCollection 2015 Sep.


G4-associated human diseases.

Maizels N.

EMBO Rep. 2015 Aug;16(8):910-22. doi: 10.15252/embr.201540607. Epub 2015 Jul 6. Review.


MRE11-deficiency associated with improved long-term disease free survival and overall survival in a subset of stage III colon cancer patients in randomized CALGB 89803 trial.

Pavelitz T, Renfro L, Foster NR, Caracol A, Welsch P, Lao VV, Grady WB, Niedzwiecki D, Saltz LB, Bertagnolli MM, Goldberg RM, Rabinovitch PS, Emond M, Monnat RJ Jr, Maizels N.

PLoS One. 2014 Oct 13;9(10):e108483. doi: 10.1371/journal.pone.0108483. eCollection 2014.


Regulation of gene expression by the BLM helicase correlates with the presence of G-quadruplex DNA motifs.

Nguyen GH, Tang W, Robles AI, Beyer RP, Gray LT, Welsh JA, Schetter AJ, Kumamoto K, Wang XW, Hickson ID, Maizels N, Monnat RJ Jr, Harris CC.

Proc Natl Acad Sci U S A. 2014 Jul 8;111(27):9905-10. doi: 10.1073/pnas.1404807111. Epub 2014 Jun 23.


Ultrasensitive isolation, identification and quantification of DNA-protein adducts by ELISA-based RADAR assay.

Kiianitsa K, Maizels N.

Nucleic Acids Res. 2014 Jul;42(13):e108. doi: 10.1093/nar/gku490. Epub 2014 Jun 9.


CpG island methylator phenotype is associated with response to adjuvant irinotecan-based therapy for stage III colon cancer.

Shiovitz S, Bertagnolli MM, Renfro LA, Nam E, Foster NR, Dzieciatkowski S, Luo Y, Lao VV, Monnat RJ Jr, Emond MJ, Maizels N, Niedzwiecki D, Goldberg RM, Saltz LB, Venook A, Warren RS, Grady WM; Alliance for Clinical Trials in Oncology.

Gastroenterology. 2014 Sep;147(3):637-45. doi: 10.1053/j.gastro.2014.05.009. Epub 2014 May 21.


G quadruplexes are genomewide targets of transcriptional helicases XPB and XPD.

Gray LT, Vallur AC, Eddy J, Maizels N.

Nat Chem Biol. 2014 Apr;10(4):313-8. doi: 10.1038/nchembio.1475. Epub 2014 Mar 9.


Homology-directed repair of DNA nicks via pathways distinct from canonical double-strand break repair.

Davis L, Maizels N.

Proc Natl Acad Sci U S A. 2014 Mar 11;111(10):E924-32. doi: 10.1073/pnas.1400236111. Epub 2014 Feb 20.


Novel fluorescent genome editing reporters for monitoring DNA repair pathway utilization at endonuclease-induced breaks.

Kuhar R, Gwiazda KS, Humbert O, Mandt T, Pangallo J, Brault M, Khan I, Maizels N, Rawlings DJ, Scharenberg AM, Certo MT.

Nucleic Acids Res. 2014 Jan;42(1):e4. doi: 10.1093/nar/gkt872. Epub 2013 Oct 10.


Genome engineering with Cre-loxP.

Maizels N.

J Immunol. 2013 Jul 1;191(1):5-6. doi: 10.4049/jimmunol.1301241. No abstract available.


Molecular and genetic bases of disease.

Maizels N, Lupski JR.

Curr Opin Genet Dev. 2013 Jun;23(3):229-31. doi: 10.1016/j.gde.2013.05.006. Epub 2013 Jun 19. No abstract available.


The G4 genome.

Maizels N, Gray LT.

PLoS Genet. 2013 Apr;9(4):e1003468. doi: 10.1371/journal.pgen.1003468. Epub 2013 Apr 18.


A rapid and sensitive assay for DNA-protein covalent complexes in living cells.

Kiianitsa K, Maizels N.

Nucleic Acids Res. 2013 May;41(9):e104. doi: 10.1093/nar/gkt171. Epub 2013 Mar 21.


Epigenetic modification of the repair donor regulates targeted gene correction.

Humbert O, Maizels N.

Mol Ther Nucleic Acids. 2012 Oct 23;1:e49. doi: 10.1038/mtna.2012.42.


G4 motifs in human genes.

Maizels N.

Ann N Y Acad Sci. 2012 Sep;1267:53-60. doi: 10.1111/j.1749-6632.2012.06586.x.

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