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Best matches for "drug repositioning" OR "drug repurposing":

Drug repositioning and repurposing: terminology and definitions in literature. Langedijk J et al. Drug Discov Today. (2015)

Drug repurposing in cancer. Sleire L et al. Pharmacol Res. (2017)

Revisiting Repurposing. Sharlow ER et al. Assay Drug Dev Technol. (2016)

Search results

Items: 1 to 20 of 2246

1.

Commercial drugs containing flavonoids are active in mice with malaria and in vitro against chloroquine-resistant Plasmodium falciparum.

Penna-Coutinho J, Aguiar AC, Krettli/ AU.

Mem Inst Oswaldo Cruz. 2018 Dec 6;113(12):e180279. doi: 10.1590/0074-02760180279.

PMID:
30540020
2.

Basics on the use of acid-sensing ion channels' inhibitors as therapeutics.

Dibas J, Al-Saad H, Dibas A.

Neural Regen Res. 2019 Mar;14(3):395-398. doi: 10.4103/1673-5374.245466. Review.

PMID:
30539804
3.

miR-9 Upregulation Integrates Post-ischemic Neuronal Survival and Regeneration In Vitro.

Nampoothiri SS, Rajanikant GK.

Cell Mol Neurobiol. 2018 Dec 11. doi: 10.1007/s10571-018-0642-1. [Epub ahead of print]

PMID:
30539420
4.

GPER is a mechanoregulator of pancreatic stellate cells and the tumor microenvironment.

Cortes E, Sarper M, Robinson B, Lachowski D, Chronopoulos A, Thorpe SD, Lee DA, Del Río Hernández AE.

EMBO Rep. 2018 Dec 11. pii: e46556. doi: 10.15252/embr.201846556. [Epub ahead of print]

PMID:
30538117
5.

Structural Immunology of Complement Receptors 3 and 4.

Vorup-Jensen T, Jensen RK.

Front Immunol. 2018 Nov 26;9:2716. doi: 10.3389/fimmu.2018.02716. eCollection 2018. Review.

6.

PathFX provides mechanistic insights into drug efficacy and safety for regulatory review and therapeutic development.

Wilson JL, Racz R, Liu T, Adeniyi O, Sun J, Ramamoorthy A, Pacanowski M, Altman R.

PLoS Comput Biol. 2018 Dec 7;14(12):e1006614. doi: 10.1371/journal.pcbi.1006614. eCollection 2018 Dec.

7.

Multistage Antiplasmodium Activity of Astemizole Analogues and Inhibition of Hemozoin Formation as a Contributor to Their Mode of Action.

Kumar M, Okombo J, Mambwe D, Taylor D, Lawrence N, Reader J, Watt MV, Fontinha D, Sanches-Vaz M, C Bezuidenhout B, Lauterbach S, Liebenberg D, Birkholtz LM, Coetzer TL, Prudêncio M, Egan TJ, Wittlin S, Chibale K.

ACS Infect Dis. 2018 Dec 11. doi: 10.1021/acsinfecdis.8b00272. [Epub ahead of print]

PMID:
30525439
8.

The Use of Large-Scale Chemically-Induced Transcriptome Data Acquired from LINCS to Study Small Molecules.

Iwata M, Yamanishi Y.

Methods Mol Biol. 2019;1888:189-203. doi: 10.1007/978-1-4939-8891-4_11.

PMID:
30519948
9.

Evaluation of imidazole and its derivative against Newcastle disease virus infection in chicken: A drug repurposing approach.

Das M, Baro S, Kumar S.

Virus Res. 2018 Nov 30. pii: S0168-1702(18)30588-4. doi: 10.1016/j.virusres.2018.11.013. [Epub ahead of print]

PMID:
30508602
10.

Use of statins or NSAIDs and survival of patients with high-grade glioma.

Seliger C, Schaertl J, Gerken M, Luber C, Proescholdt M, Riemenschneider MJ, Leitzmann MF, Hau P, Klinkhammer-Schalke M.

PLoS One. 2018 Dec 3;13(12):e0207858. doi: 10.1371/journal.pone.0207858. eCollection 2018.

11.

AS602801, an Anticancer Stem Cell Candidate Drug, Reduces Survivin Expression and Sensitizes A2780 Ovarian Cancer Stem Cells to Carboplatin and Paclitaxel.

Yamamoto M, Suzuki S, Togashi K, Sanomachi T, Seino S, Kitanaka C, Okada M.

Anticancer Res. 2018 Dec;38(12):6699-6706. doi: 10.21873/anticanres.13038.

PMID:
30504379
12.

Understanding Membrane Protein Drug Targets in Computational Perspective.

Gong J, Tan X, Chen Y, Sun P, He F, Zhang L, Li Y, Ma Z, Wang H.

Curr Drug Targets. 2018 Dec 4. doi: 10.2174/1389450120666181204164721. [Epub ahead of print]

PMID:
30516106
13.
14.

The drug repurposing landscape from 2012 to 2017: evolution, challenges, and possible solutions.

Polamreddy P, Gattu N.

Drug Discov Today. 2018 Dec 1. pii: S1359-6446(18)30282-4. doi: 10.1016/j.drudis.2018.11.022. [Epub ahead of print] Review.

PMID:
30513339
15.

Warburg effect in Gynecologic cancers.

Kobayashi Y, Banno K, Kunitomi H, Takahashi T, Takeda T, Nakamura K, Tsuji K, Tominaga E, Aoki D.

J Obstet Gynaecol Res. 2018 Dec 3. doi: 10.1111/jog.13867. [Epub ahead of print]

PMID:
30511455
16.

Repurposing approach identifies new treatment options for invasive fungal disease.

Capoci IRG, Faria DR, Sakita KM, Rodrigues-Vendramini FAV, Bonfim-Mendonça PS, Becker TCA, Kioshima ÉS, Svidzinski TIE, Maigret B.

Bioorg Chem. 2018 Nov 19;84:87-97. doi: 10.1016/j.bioorg.2018.11.019. [Epub ahead of print]

PMID:
30496872
17.

Paradigm Shift in Drug Re-purposing From Phenalenone to Phenaleno-Furanone to Combat Multi-Drug Resistant Salmonella enterica Serovar Typhi.

Mujawar S, Gatherer D, Lahiri C.

Front Cell Infect Microbiol. 2018 Nov 14;8:402. doi: 10.3389/fcimb.2018.00402. eCollection 2018.

18.

Drug repurposing: Heart failure drug effective in medulloblastoma.

Crunkhorn S.

Nat Rev Drug Discov. 2018 Nov 28;17(12):864. doi: 10.1038/nrd.2018.213. No abstract available.

PMID:
30482959
19.

Columbia Open Health Data, clinical concept prevalence and co-occurrence from electronic health records.

Ta CN, Dumontier M, Hripcsak G, Tatonetti NP, Weng C.

Sci Data. 2018 Nov 27;5:180273. doi: 10.1038/sdata.2018.273.

20.

Current state and outlook for drug repositioning anticipated in the field of ovarian cancer.

Kobayashi Y, Banno K, Kunitomi H, Tominaga E, Aoki D.

J Gynecol Oncol. 2018 Oct 8. doi: 10.3802/jgo.2019.30.e10. [Epub ahead of print] Review.

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