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Items: 1 to 20 of 36

1.

Neutrophils escort circulating tumour cells to enable cell cycle progression.

Szczerba BM, Castro-Giner F, Vetter M, Krol I, Gkountela S, Landin J, Scheidmann MC, Donato C, Scherrer R, Singer J, Beisel C, Kurzeder C, Heinzelmann-Schwarz V, Rochlitz C, Weber WP, Beerenwinkel N, Aceto N.

Nature. 2019 Feb 6. doi: 10.1038/s41586-019-0915-y. [Epub ahead of print]

PMID:
30728496
2.

Circulating Tumor Cell Clustering Shapes DNA Methylation to Enable Metastasis Seeding.

Gkountela S, Castro-Giner F, Szczerba BM, Vetter M, Landin J, Scherrer R, Krol I, Scheidmann MC, Beisel C, Stirnimann CU, Kurzeder C, Heinzelmann-Schwarz V, Rochlitz C, Weber WP, Aceto N.

Cell. 2019 Jan 10;176(1-2):98-112.e14. doi: 10.1016/j.cell.2018.11.046.

3.

Denosumab treatment is associated with the absence of circulating tumor cells in patients with breast cancer.

Vetter M, Landin J, Szczerba BM, Castro-Giner F, Gkountela S, Donato C, Krol I, Scherrer R, Balmelli C, Malinovska A, Zippelius A, Kurzeder C, Heinzelmann-Schwarz V, Weber WP, Rochlitz C, Aceto N.

Breast Cancer Res. 2018 Nov 20;20(1):141. doi: 10.1186/s13058-018-1067-y.

4.

Detection of circulating tumour cell clusters in human glioblastoma.

Krol I, Castro-Giner F, Maurer M, Gkountela S, Szczerba BM, Scherrer R, Coleman N, Carreira S, Bachmann F, Anderson S, Engelhardt M, Lane H, Evans TRJ, Plummer R, Kristeleit R, Lopez J, Aceto N.

Br J Cancer. 2018 Aug;119(4):487-491. doi: 10.1038/s41416-018-0186-7. Epub 2018 Aug 1.

PMID:
30065256
5.

Cancer Diagnosis Using a Liquid Biopsy: Challenges and Expectations.

Castro-Giner F, Gkountela S, Donato C, Alborelli I, Quagliata L, Ng CKY, Piscuoglio S, Aceto N.

Diagnostics (Basel). 2018 May 9;8(2). pii: E31. doi: 10.3390/diagnostics8020031. Review.

6.

Beyond Enumeration: Functional and Computational Analysis of Circulating Tumor Cells to Investigate Cancer Metastasis.

Castro-Giner F, Scheidmann MC, Aceto N.

Front Med (Lausanne). 2018 Feb 19;5:34. doi: 10.3389/fmed.2018.00034. eCollection 2018. Review.

7.

AR Expression in Breast Cancer CTCs Associates with Bone Metastases.

Aceto N, Bardia A, Wittner BS, Donaldson MC, O'Keefe R, Engstrom A, Bersani F, Zheng Y, Comaills V, Niederhoffer K, Zhu H, Mackenzie O, Shioda T, Sgroi D, Kapur R, Ting DT, Moy B, Ramaswamy S, Toner M, Haber DA, Maheswaran S.

Mol Cancer Res. 2018 Apr;16(4):720-727. doi: 10.1158/1541-7786.MCR-17-0480. Epub 2018 Feb 16.

PMID:
29453314
8.

Microfluidic isolation of platelet-covered circulating tumor cells.

Jiang X, Wong KHK, Khankhel AH, Zeinali M, Reategui E, Phillips MJ, Luo X, Aceto N, Fachin F, Hoang AN, Kim W, Jensen AE, Sequist LV, Maheswaran S, Haber DA, Stott SL, Toner M.

Lab Chip. 2017 Oct 11;17(20):3498-3503. doi: 10.1039/c7lc00654c.

9.

SHP2 regulates proliferation and tumorigenicity of glioma stem cells.

Roccograndi L, Binder ZA, Zhang L, Aceto N, Zhang Z, Bentires-Alj M, Nakano I, Dahmane N, O'Rourke DM.

J Neurooncol. 2017 Dec;135(3):487-496. doi: 10.1007/s11060-017-2610-x. Epub 2017 Aug 29.

PMID:
28852935
10.

Inflammatory breast cancer: a model for investigating cluster-based dissemination.

Jolly MK, Boareto M, Debeb BG, Aceto N, Farach-Carson MC, Woodward WA, Levine H.

NPJ Breast Cancer. 2017 Jun 6;3:21. doi: 10.1038/s41523-017-0023-9. eCollection 2017.

11.

Expression of β-globin by cancer cells promotes cell survival during blood-borne dissemination.

Zheng Y, Miyamoto DT, Wittner BS, Sullivan JP, Aceto N, Jordan NV, Yu M, Karabacak NM, Comaills V, Morris R, Desai R, Desai N, Emmons E, Milner JD, Lee RJ, Wu CL, Sequist LV, Haas W, Ting DT, Toner M, Ramaswamy S, Maheswaran S, Haber DA.

Nat Commun. 2017 Feb 9;8:14344. doi: 10.1038/ncomms14344.

12.

Genomic Instability Is Induced by Persistent Proliferation of Cells Undergoing Epithelial-to-Mesenchymal Transition.

Comaills V, Kabeche L, Morris R, Buisson R, Yu M, Madden MW, LiCausi JA, Boukhali M, Tajima K, Pan S, Aceto N, Sil S, Zheng Y, Sundaresan T, Yae T, Jordan NV, Miyamoto DT, Ting DT, Ramaswamy S, Haas W, Zou L, Haber DA, Maheswaran S.

Cell Rep. 2016 Dec 6;17(10):2632-2647. doi: 10.1016/j.celrep.2016.11.022.

13.

Recent advances in the biology of human circulating tumour cells and metastasis.

Gkountela S, Szczerba B, Donato C, Aceto N.

ESMO Open. 2016 Aug 3;1(4):e000078. eCollection 2016. Review.

14.

Stem-like features of cancer cells on their way to metastasis.

Gkountela S, Aceto N.

Biol Direct. 2016 Jul 26;11:33. doi: 10.1186/s13062-016-0135-4. Review.

15.

A tunable delivery platform to provide local chemotherapy for pancreatic ductal adenocarcinoma.

Indolfi L, Ligorio M, Ting DT, Xega K, Tzafriri AR, Bersani F, Aceto N, Thapar V, Fuchs BC, Deshpande V, Baker AB, Ferrone CR, Haber DA, Langer R, Clark JW, Edelman ER.

Biomaterials. 2016 Jul;93:71-82. doi: 10.1016/j.biomaterials.2016.03.044. Epub 2016 Mar 31.

16.

En Route to Metastasis: Circulating Tumor Cell Clusters and Epithelial-to-Mesenchymal Transition.

Aceto N, Toner M, Maheswaran S, Haber DA.

Trends Cancer. 2015 Sep;1(1):44-52. doi: 10.1016/j.trecan.2015.07.006. Epub 2015 Sep 28. Review.

PMID:
28741562
17.

A microfluidic device for label-free, physical capture of circulating tumor cell clusters.

Sarioglu AF, Aceto N, Kojic N, Donaldson MC, Zeinali M, Hamza B, Engstrom A, Zhu H, Sundaresan TK, Miyamoto DT, Luo X, Bardia A, Wittner BS, Ramaswamy S, Shioda T, Ting DT, Stott SL, Kapur R, Maheswaran S, Haber DA, Toner M.

Nat Methods. 2015 Jul;12(7):685-91. doi: 10.1038/nmeth.3404. Epub 2015 May 18.

18.

Tunable nanostructured coating for the capture and selective release of viable circulating tumor cells.

Reátegui E, Aceto N, Lim EJ, Sullivan JP, Jensen AE, Zeinali M, Martel JM, Aranyosi AJ, Li W, Castleberry S, Bardia A, Sequist LV, Haber DA, Maheswaran S, Hammond PT, Toner M, Stott SL.

Adv Mater. 2015 Mar 4;27(9):1593-9. doi: 10.1002/adma.201404677. Epub 2015 Jan 15.

19.

Single-cell RNA sequencing identifies extracellular matrix gene expression by pancreatic circulating tumor cells.

Ting DT, Wittner BS, Ligorio M, Vincent Jordan N, Shah AM, Miyamoto DT, Aceto N, Bersani F, Brannigan BW, Xega K, Ciciliano JC, Zhu H, MacKenzie OC, Trautwein J, Arora KS, Shahid M, Ellis HL, Qu N, Bardeesy N, Rivera MN, Deshpande V, Ferrone CR, Kapur R, Ramaswamy S, Shioda T, Toner M, Maheswaran S, Haber DA.

Cell Rep. 2014 Sep 25;8(6):1905-1918. doi: 10.1016/j.celrep.2014.08.029. Epub 2014 Sep 18.

20.

Circulating tumor cell clusters are oligoclonal precursors of breast cancer metastasis.

Aceto N, Bardia A, Miyamoto DT, Donaldson MC, Wittner BS, Spencer JA, Yu M, Pely A, Engstrom A, Zhu H, Brannigan BW, Kapur R, Stott SL, Shioda T, Ramaswamy S, Ting DT, Lin CP, Toner M, Haber DA, Maheswaran S.

Cell. 2014 Aug 28;158(5):1110-1122. doi: 10.1016/j.cell.2014.07.013.

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