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Items: 1 to 20 of 48

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1.

Development of Macrocycle Kinase Inhibitors for ALK2 Using Fibrodysplasia Ossificans Progressiva-Derived Endothelial Cells.

Sánchez-Duffhues G, Williams E, Benderitter P, Orlova V, van Wijhe M, Garcia de Vinuesa A, Kerr G, Caradec J, Lodder K, de Boer HC, Goumans MJ, Eekhoff EMW, Morales-Piga A, Bachiller-Corral J, Koolwijk P, Bullock AN, Hoflack J, Ten Dijke P.

JBMR Plus. 2019 Oct 7;3(11):e10230. doi: 10.1002/jbm4.10230. eCollection 2019 Nov.

2.

Standardized and Scalable Assay to Study Perfused 3D Angiogenic Sprouting of iPSC-derived Endothelial Cells In Vitro.

van Duinen V, Stam W, Borgdorff V, Reijerkerk A, Orlova V, Vulto P, Hankemeier T, van Zonneveld AJ.

J Vis Exp. 2019 Nov 6;(153). doi: 10.3791/59678.

PMID:
31762444
3.

Closing the Mitochondrial Permeability Transition Pore in hiPSC-Derived Endothelial Cells Induces Glycocalyx Formation and Functional Maturation.

Tiemeier GL, Wang G, Dumas SJ, Sol WMPJ, Avramut MC, Karakach T, Orlova VV, van den Berg CW, Mummery CL, Carmeliet P, van den Berg BM, Rabelink TJ.

Stem Cell Reports. 2019 Nov 12;13(5):803-816. doi: 10.1016/j.stemcr.2019.10.005. Epub 2019 Oct 31.

4.

Homozygous Missense Variants in NTNG2, Encoding a Presynaptic Netrin-G2 Adhesion Protein, Lead to a Distinct Neurodevelopmental Disorder.

Dias CM, Punetha J, Zheng C, Mazaheri N, Rad A, Efthymiou S, Petersen A, Dehghani M, Pehlivan D, Partlow JN, Posey JE, Salpietro V, Gezdirici A, Malamiri RA, Al Menabawy NM, Selim LA, Vahidi Mehrjardi MY, Banu S, Polla DL, Yang E, Rezazadeh Varaghchi J, Mitani T, van Beusekom E, Najafi M, Sedaghat A, Keller-Ramey J, Durham L, Coban-Akdemir Z, Karaca E, Orlova V, Schaeken LLM, Sherafat A, Jhangiani SN, Stanley V, Shariati G, Galehdari H, Gleeson JG, Walsh CA, Lupski JR, Seiradake E, Houlden H, van Bokhoven H, Maroofian R.

Am J Hum Genet. 2019 Nov 7;105(5):1048-1056. doi: 10.1016/j.ajhg.2019.09.025. Epub 2019 Oct 24.

5.

Scalable microphysiological system to model three-dimensional blood vessels.

de Graaf MNS, Cochrane A, van den Hil FE, Buijsman W, van der Meer AD, van den Berg A, Mummery CL, Orlova VV.

APL Bioeng. 2019 Jun 21;3(2):026105. doi: 10.1063/1.5090986. eCollection 2019 Jun.

6.

Differentiation and Functional Comparison of Monocytes and Macrophages from hiPSCs with Peripheral Blood Derivatives.

Cao X, Yakala GK, van den Hil FE, Cochrane A, Mummery CL, Orlova VV.

Stem Cell Reports. 2019 Jun 11;12(6):1282-1297. doi: 10.1016/j.stemcr.2019.05.003.

7.

Quantifying Ca2+ signaling and contraction in vascular pericytes and smooth muscle cells.

Halaidych OV, Mummery CL, Orlova VV.

Biochem Biophys Res Commun. 2019 May 21;513(1):112-118. doi: 10.1016/j.bbrc.2019.03.143. Epub 2019 Mar 30.

8.

Quantitative Analysis of Intracellular Ca2+ Release and Contraction in hiPSC-Derived Vascular Smooth Muscle Cells.

Halaidych OV, Cochrane A, van den Hil FE, Mummery CL, Orlova VV.

Stem Cell Reports. 2019 Apr 9;12(4):647-656. doi: 10.1016/j.stemcr.2019.02.003. Epub 2019 Mar 7.

9.

Generation of 3 human induced pluripotent stem cell lines LUMCi005-A, B and C from a Hereditary Cerebral Hemorrhage with Amyloidosis-Dutch type patient.

Daoutsali E, Buijsen RAM, van de Pas S, Jong A', Mikkers H, Brands T, Eussen B, de Klein A, van der Graaf LM, Pepers BA, Freund C, Terwindt GM, Orlova VV, van Roon-Mom WMC.

Stem Cell Res. 2019 Jan;34:101359. doi: 10.1016/j.scr.2018.101359. Epub 2018 Dec 14.

10.

Microfluidic Assay for the Assessment of Leukocyte Adhesion to Human Induced Pluripotent Stem Cell-derived Endothelial Cells (hiPSC-ECs).

Halaidych OV, van den Hil F, Mummery CL, Orlova VV.

J Vis Exp. 2018 Nov 26;(141). doi: 10.3791/58678.

PMID:
30531715
11.

Advanced in vitro models of vascular biology: Human induced pluripotent stem cells and organ-on-chip technology.

Cochrane A, Albers HJ, Passier R, Mummery CL, van den Berg A, Orlova VV, van der Meer AD.

Adv Drug Deliv Rev. 2019 Feb 1;140:68-77. doi: 10.1016/j.addr.2018.06.007. Epub 2018 Jun 23. Review.

12.

Inflammatory Responses and Barrier Function of Endothelial Cells Derived from Human Induced Pluripotent Stem Cells.

Halaidych OV, Freund C, van den Hil F, Salvatori DCF, Riminucci M, Mummery CL, Orlova VV.

Stem Cell Reports. 2018 May 8;10(5):1642-1656. doi: 10.1016/j.stemcr.2018.03.012. Epub 2018 Apr 12.

13.

Squaramide-Based Supramolecular Materials for Three-Dimensional Cell Culture of Human Induced Pluripotent Stem Cells and Their Derivatives.

Tong C, Liu T, Saez Talens V, Noteborn WEM, Sharp TH, Hendrix MMRM, Voets IK, Mummery CL, Orlova VV, Kieltyka RE.

Biomacromolecules. 2018 Apr 9;19(4):1091-1099. doi: 10.1021/acs.biomac.7b01614. Epub 2018 Mar 12.

14.

MUSCLEMOTION: A Versatile Open Software Tool to Quantify Cardiomyocyte and Cardiac Muscle Contraction In Vitro and In Vivo.

Sala L, van Meer BJ, Tertoolen LGJ, Bakkers J, Bellin M, Davis RP, Denning C, Dieben MAE, Eschenhagen T, Giacomelli E, Grandela C, Hansen A, Holman ER, Jongbloed MRM, Kamel SM, Koopman CD, Lachaud Q, Mannhardt I, Mol MPH, Mosqueira D, Orlova VV, Passier R, Ribeiro MC, Saleem U, Smith GL, Burton FL, Mummery CL.

Circ Res. 2018 Feb 2;122(3):e5-e16. doi: 10.1161/CIRCRESAHA.117.312067. Epub 2017 Dec 27. Review.

15.

Human Pluripotent Stem Cell Differentiation into Functional Epicardial Progenitor Cells.

Guadix JA, Orlova VV, Giacomelli E, Bellin M, Ribeiro MC, Mummery CL, Pérez-Pomares JM, Passier R.

Stem Cell Reports. 2017 Dec 12;9(6):1754-1764. doi: 10.1016/j.stemcr.2017.10.023. Epub 2017 Nov 22.

16.

A COUP-TFII Human Embryonic Stem Cell Reporter Line to Identify and Select Atrial Cardiomyocytes.

Schwach V, Verkerk AO, Mol M, Monshouwer-Kloots JJ, Devalla HD, Orlova VV, Anastassiadis K, Mummery CL, Davis RP, Passier R.

Stem Cell Reports. 2017 Dec 12;9(6):1765-1779. doi: 10.1016/j.stemcr.2017.10.024. Epub 2017 Nov 22.

17.

Co-Differentiation of Human Pluripotent Stem Cells-Derived Cardiomyocytes and Endothelial Cells from Cardiac Mesoderm Provides a Three-Dimensional Model of Cardiac Microtissue.

Giacomelli E, Bellin M, Orlova VV, Mummery CL.

Curr Protoc Hum Genet. 2017 Oct 18;95:21.9.1-21.9.22. doi: 10.1002/cphg.46.

PMID:
29044469
18.

Three-dimensional cardiac microtissues composed of cardiomyocytes and endothelial cells co-differentiated from human pluripotent stem cells.

Giacomelli E, Bellin M, Sala L, van Meer BJ, Tertoolen LG, Orlova VV, Mummery CL.

Development. 2017 Mar 15;144(6):1008-1017. doi: 10.1242/dev.143438.

19.

SnapShot: Key Advances in hiPSC Disease Modeling.

Orlova V, Mummery C.

Cell Stem Cell. 2016 Mar 3;18(3):422. doi: 10.1016/j.stem.2016.02.013.

20.

Complex Tissue and Disease Modeling using hiPSCs.

Passier R, Orlova V, Mummery C.

Cell Stem Cell. 2016 Mar 3;18(3):309-21. doi: 10.1016/j.stem.2016.02.011. Review.

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