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Best matches for "Tyrosine-Protein Kinase" and docking:

Src protein-tyrosine kinase structure and regulation. Roskoski R Jr et al. Biochem Biophys Res Commun. (2004)

Synthesis, Docking Study and Kinase Inhibitory Activity of a Number of New Substituted Pyrazolo[3,4-c]pyridines. Sklepari M et al. Chem Pharm Bull (Tokyo). (2017)

Nuclear protein kinase CLK1 uses a non-traditional docking mechanism to select physiological substrates. Keshwani MM et al. Biochem J. (2015)

Search results

Items: 1 to 20 of 43


Phosphorylation of deinococcal RecA affects its structural and functional dynamics implicated for its roles in radioresistance of Deinococcus radiodurans.

Sharma DK, Siddiqui MQ, Gadewal N, Choudhary RK, Varma AK, Misra HS, Rajpurohit YS.

J Biomol Struct Dyn. 2019 Jan 27:1-10. doi: 10.1080/07391102.2019.1568916. [Epub ahead of print]


JAK2 regulation by licochalcone H inhibits the cell growth and induces apoptosis in oral squamous cell carcinoma.

Oh HN, Oh KB, Lee MH, Seo JH, Kim E, Yoon G, Cho SS, Cho YS, Choi HW, Chae JI, Shim JH.

Phytomedicine. 2019 Jan;52:60-69. doi: 10.1016/j.phymed.2018.09.180. Epub 2018 Sep 18.


Application of molecular framework-based data-mining method in the search for beta-secretase 1 inhibitors through drug repurposing.

Ion GND, Mihai DP, Lupascu G, Nitulescu GM.

J Biomol Struct Dyn. 2018 Nov 13:1-12. doi: 10.1080/07391102.2018.1526115. [Epub ahead of print]


Introducing novel potent anticancer agents of 1H-benzo[f]chromene scaffolds, targeting c-Src kinase enzyme with MDA-MB-231 cell line anti-invasion effect.

Ahmed HEA, El-Nassag MAA, Hassan AH, Okasha RM, Ihmaid S, Fouda AM, Afifi TH, Aljuhani A, El-Agrody AM.

J Enzyme Inhib Med Chem. 2018 Dec;33(1):1074-1088. doi: 10.1080/14756366.2018.1476503.


The First Pentacyclic Triterpenoid Gypsogenin Derivative Exhibiting Anti-ABL1 Kinase and Anti-chronic Myelogenous Leukemia Activities.

Ciftci HI, Ozturk SE, Ali TFS, Radwan MO, Tateishi H, Koga R, Ocak Z, Can M, Otsuka M, Fujita M.

Biol Pharm Bull. 2018 Apr 1;41(4):570-574. doi: 10.1248/bpb.b17-00902. Epub 2018 Jan 30.


Discovery of novel 2,4-diarylaminopyrimidine analogues as ALK and ROS1 dual inhibitors to overcome crizotinib-resistant mutants including G1202R.

Wang Y, Chen S, Hu G, Wang J, Gou W, Zuo D, Gu Y, Gong P, Zhai X.

Eur J Med Chem. 2018 Jan 1;143:123-136. doi: 10.1016/j.ejmech.2017.11.008. Epub 2017 Nov 6.


Natural-Based Indirubins Display Potent Cytotoxicity toward Wild-Type and T315I-Resistant Leukemia Cell Lines.

Gaboriaud-Kolar N, Myrianthopoulos V, Vougogiannopoulou K, Gerolymatos P, Horne DA, Jove R, Mikros E, Nam S, Skaltsounis AL.

J Nat Prod. 2016 Oct 28;79(10):2464-2471. Epub 2016 Oct 11.


Discovery of Multitarget Antivirals Acting on Both the Dengue Virus NS5-NS3 Interaction and the Host Src/Fyn Kinases.

Vincetti P, Caporuscio F, Kaptein S, Gioiello A, Mancino V, Suzuki Y, Yamamoto N, Crespan E, Lossani A, Maga G, Rastelli G, Castagnolo D, Neyts J, Leyssen P, Costantino G, Radi M.

J Med Chem. 2015 Jun 25;58(12):4964-75. doi: 10.1021/acs.jmedchem.5b00108. Epub 2015 Jun 15.


A Discovery Strategy for Selective Inhibitors of c-Src in Complex with the Focal Adhesion Kinase SH3/SH2-binding Region.

Moroco JA, Baumgartner MP, Rust HL, Choi HG, Hur W, Gray NS, Camacho CJ, Smithgall TE.

Chem Biol Drug Des. 2015 Aug;86(2):144-55. doi: 10.1111/cbdd.12473. Epub 2014 Nov 28.


Isoliquiritigenin induces apoptosis and inhibits xenograft tumor growth of human lung cancer cells by targeting both wild type and L858R/T790M mutant EGFR.

Jung SK, Lee MH, Lim DY, Kim JE, Singh P, Lee SY, Jeong CH, Lim TG, Chen H, Chi YI, Kundu JK, Lee NH, Lee CC, Cho YY, Bode AM, Lee KW, Dong Z.

J Biol Chem. 2014 Dec 26;289(52):35839-48. doi: 10.1074/jbc.M114.585513. Epub 2014 Nov 3.


Discovery of 4,6-substituted-(diaphenylamino)quinazolines as potent c-Src inhibitors.

Li JR, Li DD, Fang F, Du QR, Lin L, Sun J, Qian Y, Zhu HL.

Org Biomol Chem. 2013 Dec 28;11(48):8375-86. doi: 10.1039/c3ob41161c. Epub 2013 Oct 31.


Acquired substrate preference for GAB1 protein bestows transforming activity to ERBB2 kinase lung cancer mutants.

Fan YX, Wong L, Marino MP, Ou W, Shen Y, Wu WJ, Wong KK, Reiser J, Johnson GR.

J Biol Chem. 2013 Jun 7;288(23):16895-904. doi: 10.1074/jbc.M112.434217. Epub 2013 Apr 23.


De novo design of protein kinase inhibitors by in silico identification of hinge region-binding fragments.

Urich R, Wishart G, Kiczun M, Richters A, Tidten-Luksch N, Rauh D, Sherborne B, Wyatt PG, Brenk R.

ACS Chem Biol. 2013 May 17;8(5):1044-52. doi: 10.1021/cb300729y. Epub 2013 Mar 27.


Theoretical studies of QSAR and molecular design on a novel series of ethynyl-3-quinolinecarbonitriles as SRC inhibitors.

Fang DQ, Wu WJ, Zhang R, Zeng GH, Zheng KC.

Chem Biol Drug Des. 2012 Jul;80(1):134-47. doi: 10.1111/j.1747-0285.2012.01385.x. Epub 2012 Apr 27.


NADPH-oxidase-dependent reactive oxygen species mediate EGFR transactivation by FPRL1 in WKYMVm-stimulated human lung cancer cells.

Cattaneo F, Iaccio A, Guerra G, Montagnani S, Ammendola R.

Free Radic Biol Med. 2011 Sep 15;51(6):1126-36. doi: 10.1016/j.freeradbiomed.2011.05.040. Epub 2011 Jun 12.


Optimized hydrophobic interactions and hydrogen bonding at the target-ligand interface leads the pathways of drug-designing.

Patil R, Das S, Stanley A, Yadav L, Sudhakar A, Varma AK.

PLoS One. 2010 Aug 16;5(8):e12029. doi: 10.1371/journal.pone.0012029.


Cloning, characterization, and expression pattern of Atlantic halibut (Hippoglossus hippoglossus L.) CD4-2, Lck, and ZAP-70.

Øvergård AC, Nerland AH, Patel S.

Fish Shellfish Immunol. 2010 Dec;29(6):987-97. doi: 10.1016/j.fsi.2010.08.011. Epub 2010 Aug 20.


Differential phosphorylation of the docking protein Gab1 by c-Src and the hepatocyte growth factor receptor regulates different aspects of cell functions.

Chan PC, Sudhakar JN, Lai CC, Chen HC.

Oncogene. 2010 Feb 4;29(5):698-710. doi: 10.1038/onc.2009.363. Epub 2009 Nov 2.


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