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Best matches for "Serotonin Receptor" and docking:

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Items: 1 to 20 of 123

1.

Structural determinants influencing halogen bonding: a case study on azinesulfonamide analogs of aripiprazole as 5-HT1A, 5-HT7, and D2 receptor ligands.

Marciniec K, Kurczab R, Książek M, Bębenek E, Chrobak E, Satała G, Bojarski AJ, Kusz J, Zajdel P.

Chem Cent J. 2018 May 11;12(1):55. doi: 10.1186/s13065-018-0422-5.

2.

Structural insights into serotonin receptor ligands polypharmacology.

Podlewska S, Kafel R, Lacivita E, Satała G, Kooistra AJ, Vass M, de Graaf C, Leopoldo M, Bojarski AJ, Mordalski S.

Eur J Med Chem. 2018 May 10;151:797-814. doi: 10.1016/j.ejmech.2018.04.010. Epub 2018 Apr 6.

PMID:
29679900
3.

Identification of natural products as novel ligands for the human 5-HT2C receptor.

Peng Y, Zhao S, Wu Y, Cao H, Xu Y, Liu X, Shui W, Cheng J, Zhao S, Shen L, Ma J, Quinn RJ, Stevens RC, Zhong G, Liu ZJ.

Biophys Rep. 2018;4(1):50-61. doi: 10.1007/s41048-018-0047-1. Epub 2018 Mar 9.

4.

5-HT1A and 5-HT2A receptors affinity, docking studies and pharmacological evaluation of a series of 8-acetyl-7-hydroxy-4-methylcoumarin derivatives.

Ostrowska K, Grzeszczuk D, Głuch-Lutwin M, Gryboś A, Siwek A, Leśniak A, Sacharczuk M, Trzaskowski B.

Bioorg Med Chem. 2018 Jan 15;26(2):527-535. doi: 10.1016/j.bmc.2017.12.016. Epub 2017 Dec 9.

PMID:
29269256
5.

Computational and biological evidences on the serotonergic involvement of SeTACN antidepressant-like effect in mice.

Fronza MG, Brod LMP, Casaril AM, Sacramento M, Alves D, Savegnago L.

PLoS One. 2017 Nov 1;12(11):e0187445. doi: 10.1371/journal.pone.0187445. eCollection 2017. Erratum in: PLoS One. 2017 Dec 14;12 (12 ):e0189975.

6.

Template selection and refinement considerations for modelling aminergic GPCR-ligand complexes.

Urmi KF, Finch AM, Griffith R.

J Mol Graph Model. 2017 Sep;76:488-503. doi: 10.1016/j.jmgm.2017.07.030. Epub 2017 Jul 31.

PMID:
28818718
7.

Mechanism Exploration of Arylpiperazine Derivatives Targeting the 5-HT2A Receptor by In Silico Methods.

Lin F, Li F, Wang C, Wang J, Yang Y, Yang L, Li Y.

Molecules. 2017 Jun 26;22(7). pii: E1064. doi: 10.3390/molecules22071064.

8.

Synthesis of a new series of aryl/heteroarylpiperazinyl derivatives of 8-acetyl-7-hydroxy-4-methylcoumarin with low nanomolar 5-HT1A affinities.

Ostrowska K, Młodzikowska K, Głuch-Lutwin M, Gryboś A, Siwek A.

Eur J Med Chem. 2017 Sep 8;137:108-116. doi: 10.1016/j.ejmech.2017.05.047. Epub 2017 May 26.

PMID:
28575721
9.

The impact of the halogen bonding on D2 and 5-HT1A/5-HT7 receptor activity of azinesulfonamides of 4-[(2-ethyl)piperidinyl-1-yl]phenylpiperazines with antipsychotic and antidepressant properties.

Partyka A, Kurczab R, Canale V, Satała G, Marciniec K, Pasierb A, Jastrzębska-Więsek M, Pawłowski M, Wesołowska A, Bojarski AJ, Zajdel P.

Bioorg Med Chem. 2017 Jul 15;25(14):3638-3648. doi: 10.1016/j.bmc.2017.04.046. Epub 2017 May 4.

PMID:
28529043
10.

4-Phenyl quinoline derivatives as potential serotonin receptor ligands with antiproliferative activity.

Joshi PV, Sayed AA, RaviKumar A, Puranik VG, Zinjarde SS.

Eur J Med Chem. 2017 Aug 18;136:246-258. doi: 10.1016/j.ejmech.2017.05.002. Epub 2017 May 2.

PMID:
28499170
11.

The computer-aided discovery of novel family of the 5-HT6 serotonin receptor ligands among derivatives of 4-benzyl-1,3,5-triazine.

Łażewska D, Kurczab R, Więcek M, Kamińska K, Satała G, Jastrzębska-Więsek M, Partyka A, Bojarski AJ, Wesołowska A, Kieć-Kononowicz K, Handzlik J.

Eur J Med Chem. 2017 Jul 28;135:117-124. doi: 10.1016/j.ejmech.2017.04.033. Epub 2017 Apr 13.

PMID:
28441580
12.

Subtle Differences among 5-HT3AC, 5-HT3AD, and 5-HT3AE Receptors Are Revealed by Partial Agonists.

Price KL, Hirayama Y, Lummis SCR.

ACS Chem Neurosci. 2017 May 17;8(5):1085-1091. doi: 10.1021/acschemneuro.6b00416. Epub 2017 Apr 3.

PMID:
28367632
13.

From Homology Models to a Set of Predictive Binding Pockets-a 5-HT1A Receptor Case Study.

Warszycki D, Rueda M, Mordalski S, Kristiansen K, Satała G, Rataj K, Chilmonczyk Z, Sylte I, Abagyan R, Bojarski AJ.

J Chem Inf Model. 2017 Feb 27;57(2):311-321. doi: 10.1021/acs.jcim.6b00263. Epub 2017 Jan 18.

14.

Synthesis and Docking of Novel 3-Indolylpropyl Derivatives as New Polypharmacological Agents Displaying Affinity for 5-HT1A R/SERT.

Pessoa-Mahana H, Silva-Matus P, Pessoa-Mahana CD, Chung H, Iturriaga-Vásquez P, Quiroz G, Möller-Acuña P, Zapata-Torres G, Saitz-Barría C, Araya-Maturana R, Reyes-Parada M.

Arch Pharm (Weinheim). 2017 Jan;350(1). doi: 10.1002/ardp.201600271. Epub 2016 Dec 16.

PMID:
27981607
15.

Structure-Based Scaffold Repurposing for G Protein-Coupled Receptors: Transformation of Adenosine Derivatives into 5HT2B/5HT2C Serotonin Receptor Antagonists.

Tosh DK, Ciancetta A, Warnick E, Crane S, Gao ZG, Jacobson KA.

J Med Chem. 2016 Dec 22;59(24):11006-11026. doi: 10.1021/acs.jmedchem.6b01183. Epub 2016 Dec 9.

16.

Dibenzo[b,f][1,4]oxazepines and dibenzo[b,e]oxepines: Influence of the chlorine substitution pattern on the pharmacology at the H1R, H4R, 5-HT2AR and other selected GPCRs.

Naporra F, Gobleder S, Wittmann HJ, Spindler J, Bodensteiner M, Bernhardt G, Hübner H, Gmeiner P, Elz S, Strasser A.

Pharmacol Res. 2016 Nov;113(Pt A):610-625. doi: 10.1016/j.phrs.2016.09.042. Epub 2016 Sep 30.

PMID:
27697645
17.

The replacement of the 2-methoxy substituent of N-((6,6-diphenyl-1,4-dioxan-2-yl)methyl)-2-(2-methoxyphenoxy)ethan-1-amine improves the selectivity for 5-HT1A receptor over α1-adrenoceptor and D2-like receptor subtypes.

Del Bello F, Bonifazi A, Giannella M, Giorgioni G, Piergentili A, Petrelli R, Cifani C, Micioni Di Bonaventura MV, Keck TM, Mazzolari A, Vistoli G, Cilia A, Poggesi E, Matucci R, Quaglia W.

Eur J Med Chem. 2017 Jan 5;125:233-244. doi: 10.1016/j.ejmech.2016.09.026. Epub 2016 Sep 9.

PMID:
27662034
18.

5-HT7 receptor modulators: Amino groups attached to biphenyl scaffold determine functional activity.

Kim Y, Park H, Lee J, Tae J, Kim HJ, Min SJ, Rhim H, Choo H.

Eur J Med Chem. 2016 Nov 10;123:180-190. doi: 10.1016/j.ejmech.2016.07.029. Epub 2016 Jul 21.

PMID:
27475109
19.

Dysregulations of Synaptic Vesicle Trafficking in Schizophrenia.

Egbujo CN, Sinclair D, Hahn CG.

Curr Psychiatry Rep. 2016 Aug;18(8):77. doi: 10.1007/s11920-016-0710-5. Review.

20.

Structural Insights into 5-HT1A/D4 Selectivity of WAY-100635 Analogues: Molecular Modeling, Synthesis, and in Vitro Binding.

Dilly S, Liégeois JF.

J Chem Inf Model. 2016 Jul 25;56(7):1324-31. doi: 10.1021/acs.jcim.5b00753. Epub 2016 Jul 13.

PMID:
27331407

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