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A Call for Improved Reporting of Human Islet Characteristics in Research Articles.

Poitout V, Satin LS, Kahn SE, Stoffers DA, Marchetti P, Gannon M, Verchere CB, Herold KC, Myers MG Jr, Marshall SM.

Diabetes. 2018 Dec 14. pii: dbi180055. doi: 10.2337/dbi18-0055. [Epub ahead of print] No abstract available.


A call for improved reporting of human islet characteristics in research articles.

Poitout V, Satin LS, Kahn SE, Stoffers DA, Marchetti P, Gannon M, Verchere CB, Herold KC, Myers MG Jr, Marshall SM.

Diabetologia. 2018 Dec 14. doi: 10.1007/s00125-018-4784-y. [Epub ahead of print] No abstract available.


Fatty Acids and Insulin Secretion: From FFAR and Near?

Poitout V.

Diabetes. 2018 Oct;67(10):1932-1934. doi: 10.2337/dbi18-0027. No abstract available.


Increases in bioactive lipids accompany early metabolic changes associated with β-cell expansion in response to short-term high fat diet.

Seferovic MD, Beamish CA, Mosser RE, Townsend SE, Pappan K, Poitout V, Aagaard K, Gannon M.

Am J Physiol Endocrinol Metab. 2018 Aug 14. doi: 10.1152/ajpendo.00001.2018. [Epub ahead of print]


Considerations and guidelines for mouse metabolic phenotyping in diabetes research.

Alquier T, Poitout V.

Diabetologia. 2018 Mar;61(3):526-538. doi: 10.1007/s00125-017-4495-9. Epub 2017 Nov 16. Review.


Deletion of Protein Kinase D1 in Pancreatic β-Cells Impairs Insulin Secretion in High-Fat Diet-Fed Mice.

Bergeron V, Ghislain J, Vivot K, Tamarina N, Philipson LH, Fielitz J, Poitout V.

Diabetes. 2018 Jan;67(1):71-77. doi: 10.2337/db17-0982. Epub 2017 Oct 16.


Nutrient regulation of pancreatic β-cell proliferation.

Moullé VS, Ghislain J, Poitout V.

Biochimie. 2017 Dec;143:10-17. doi: 10.1016/j.biochi.2017.09.017. Epub 2017 Oct 5. Review.


Glucose and fatty acids synergistically and reversibly promote beta cell proliferation in rats.

Moullé VS, Vivot K, Tremblay C, Zarrouki B, Ghislain J, Poitout V.

Diabetologia. 2017 May;60(5):879-888. doi: 10.1007/s00125-016-4197-8. Epub 2017 Jan 11.


The Role and Future of FFA1 as a Therapeutic Target.

Ghislain J, Poitout V.

Handb Exp Pharmacol. 2017;236:159-180. doi: 10.1007/164_2016_51. Review.


The regulator of G-protein signaling RGS16 promotes insulin secretion and β-cell proliferation in rodent and human islets.

Vivot K, Moullé VS, Zarrouki B, Tremblay C, Mancini AD, Maachi H, Ghislain J, Poitout V.

Mol Metab. 2016 Aug 26;5(10):988-996. doi: 10.1016/j.molmet.2016.08.010. eCollection 2016 Oct.


Urea impairs β cell glycolysis and insulin secretion in chronic kidney disease.

Koppe L, Nyam E, Vivot K, Manning Fox JE, Dai XQ, Nguyen BN, Trudel D, Attané C, Moullé VS, MacDonald PE, Ghislain J, Poitout V.

J Clin Invest. 2016 Sep 1;126(9):3598-612. doi: 10.1172/JCI86181. Epub 2016 Aug 15.


CMPF: A Biomarker for Type 2 Diabetes Mellitus Progression?

Koppe L, Poitout V.

Trends Endocrinol Metab. 2016 Jul;27(7):439-440. doi: 10.1016/j.tem.2016.04.010. Epub 2016 Apr 27.


Central Agonism of GPR120 Acutely Inhibits Food Intake and Food Reward and Chronically Suppresses Anxiety-Like Behavior in Mice.

Auguste S, Fisette A, Fernandes MF, Hryhorczuk C, Poitout V, Alquier T, Fulton S.

Int J Neuropsychopharmacol. 2016 Jul 5;19(7). pii: pyw014. doi: 10.1093/ijnp/pyw014. Print 2016 Jul.


Dual-Reporter β-Cell-Specific Male Transgenic Rats for the Analysis of β-Cell Functional Mass and Enrichment by Flow Cytometry.

Ghislain J, Fontés G, Tremblay C, Kebede MA, Poitout V.

Endocrinology. 2016 Mar;157(3):1299-306. doi: 10.1210/en.2015-1550. Epub 2015 Dec 15.


PGC-1 coactivators in β-cells regulate lipid metabolism and are essential for insulin secretion coupled to fatty acids.

Oropeza D, Jouvet N, Bouyakdan K, Perron G, Ringuette LJ, Philipson LH, Kiss RS, Poitout V, Alquier T, Estall JL.

Mol Metab. 2015 Aug 14;4(11):811-22. doi: 10.1016/j.molmet.2015.08.001. eCollection 2015 Nov.


The ΔF508 Mutation in the Cystic Fibrosis Transmembrane Conductance Regulator Is Associated With Progressive Insulin Resistance and Decreased Functional β-Cell Mass in Mice.

Fontés G, Ghislain J, Benterki I, Zarrouki B, Trudel D, Berthiaume Y, Poitout V.

Diabetes. 2015 Dec;64(12):4112-22. doi: 10.2337/db14-0810. Epub 2015 Aug 17.


β-Arrestin Recruitment and Biased Agonism at Free Fatty Acid Receptor 1.

Mancini AD, Bertrand G, Vivot K, Carpentier É, Tremblay C, Ghislain J, Bouvier M, Poitout V.

J Biol Chem. 2015 Aug 21;290(34):21131-40. doi: 10.1074/jbc.M115.644450. Epub 2015 Jul 8.


Phenotypic Characterization of MIP-CreERT1Lphi Mice With Transgene-Driven Islet Expression of Human Growth Hormone.

Oropeza D, Jouvet N, Budry L, Campbell JE, Bouyakdan K, Lacombe J, Perron G, Bergeron V, Neuman JC, Brar HK, Fenske RJ, Meunier C, Sczelecki S, Kimple ME, Drucker DJ, Screaton RA, Poitout V, Ferron M, Alquier T, Estall JL.

Diabetes. 2015 Nov;64(11):3798-807. doi: 10.2337/db15-0272. Epub 2015 Jul 7.


An Acetate-Specific GPCR, FFAR2, Regulates Insulin Secretion.

Priyadarshini M, Villa SR, Fuller M, Wicksteed B, Mackay CR, Alquier T, Poitout V, Mancebo H, Mirmira RG, Gilchrist A, Layden BT.

Mol Endocrinol. 2015 Jul;29(7):1055-66. doi: 10.1210/me.2015-1007. Epub 2015 Jun 15.

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