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Items: 1 to 20 of 48

1.

Computational Exploration of Natural Compounds to Target Cytosolic Phospholipase A 2 Protein: A Novel Therapeutic Target for Spinal Cord Injury.

Fan H, Wang S, Zhao Q, Qin Z.

Curr Comput Aided Drug Des. 2018;14(2):117-124. doi: 10.2174/1573409914666180123100714.

PMID:
29359676
2.

Impact of tyrosine nitration at positions Tyr307 and Tyr335 on structural dynamics of Lipoprotein-associated phospholipase A2-A therapeutically important cardiovascular biomarker for atherosclerosis.

Gurung AB, Bhattacharjee A.

Int J Biol Macromol. 2018 Feb;107(Pt B):1956-1964. doi: 10.1016/j.ijbiomac.2017.10.068. Epub 2017 Oct 16.

PMID:
29051098
3.

Efficient heterologous expression, functional characterization and molecular modeling of annular seabream digestive phospholipase A2.

Smichi N, Othman H, Achouri N, Noiriel A, Triki S, Arondel V, Srairi-Abid N, Abousalham A, Gargouri Y, Miled N, Fendri A.

Chem Phys Lipids. 2018 Mar;211:16-29. doi: 10.1016/j.chemphyslip.2017.06.004. Epub 2017 Jun 15.

PMID:
28624308
4.

Phospholipase A2: Potential roles in native membrane fusion.

Dabral D, Coorssen JR.

Int J Biochem Cell Biol. 2017 Apr;85:1-5. doi: 10.1016/j.biocel.2017.01.011. Epub 2017 Jan 25. Review.

PMID:
28131878
5.

Crystal structure of a phospholipase A2 from Bothrops asper venom: Insights into a new putative "myotoxic cluster".

Salvador GH, Dos Santos JI, Lomonte B, Fontes MR.

Biochimie. 2017 Feb;133:95-102. doi: 10.1016/j.biochi.2016.12.015. Epub 2016 Dec 27.

6.

Celastrol modulates inflammation through inhibition of the catalytic activity of mediators of arachidonic acid pathway: Secretory phospholipase A2 group IIA, 5-lipoxygenase and cyclooxygenase-2.

Joshi V, Venkatesha SH, Ramakrishnan C, Nanjaraj Urs AN, Hiremath V, Moudgil KD, Velmurugan D, Vishwanath BS.

Pharmacol Res. 2016 Nov;113(Pt A):265-275. doi: 10.1016/j.phrs.2016.08.035. Epub 2016 Sep 3.

PMID:
27597642
7.

Computer-aided drug design guided by hydrogen/deuterium exchange mass spectrometry: A powerful combination for the development of potent and selective inhibitors of Group VIA calcium-independent phospholipase A2.

Mouchlis VD, Morisseau C, Hammock BD, Li S, McCammon JA, Dennis EA.

Bioorg Med Chem. 2016 Oct 15;24(20):4801-4811. doi: 10.1016/j.bmc.2016.05.009. Epub 2016 May 10.

8.

Rattlesnake Phospholipase A2 Increases CFTR-Chloride Channel Current and Corrects ∆F508CFTR Dysfunction: Impact in Cystic Fibrosis.

Faure G, Bakouh N, Lourdel S, Odolczyk N, Premchandar A, Servel N, Hatton A, Ostrowski MK, Xu H, Saul FA, Moquereau C, Bitam S, Pranke I, Planelles G, Teulon J, Herrmann H, Roldan A, Zielenkiewicz P, Dadlez M, Lukacs GL, Sermet-Gaudelus I, Ollero M, Corringer PJ, Edelman A.

J Mol Biol. 2016 Jul 17;428(14):2898-915. doi: 10.1016/j.jmb.2016.05.016. Epub 2016 May 27.

PMID:
27241308
9.

Inhibitory effect of pinostrobin from Renealmia alpinia, on the enzymatic and biological activities of a PLA2.

Gómez-Betancur I, Pereañez JA, Patiño AC, Benjumea D.

Int J Biol Macromol. 2016 Aug;89:35-42. doi: 10.1016/j.ijbiomac.2016.04.042. Epub 2016 Apr 22.

PMID:
27109758
10.

Dimethyl ester of bilirubin exhibits anti-inflammatory activity through inhibition of secretory phospholipase A2, lipoxygenase and cyclooxygenase.

Joshi V, Umashankara M, Ramakrishnan C, Nanjaraj Urs AN, Suvilesh KN, Velmurugan D, Rangappa KS, Vishwanath BS.

Arch Biochem Biophys. 2016 May 15;598:28-39. doi: 10.1016/j.abb.2016.04.003. Epub 2016 Apr 6.

PMID:
27060751
11.

Quercetin-3-O-rhamnoside from Euphorbia hirta protects against snake Venom induced toxicity.

Gopi K, Anbarasu K, Renu K, Jayanthi S, Vishwanath BS, Jayaraman G.

Biochim Biophys Acta. 2016 Jul;1860(7):1528-40. doi: 10.1016/j.bbagen.2016.03.031. Epub 2016 Mar 28.

PMID:
27033089
12.

Development of a potent 2-oxoamide inhibitor of secreted phospholipase A2 guided by molecular docking calculations and molecular dynamics simulations.

Vasilakaki S, Barbayianni E, Leonis G, Papadopoulos MG, Mavromoustakos T, Gelb MH, Kokotos G.

Bioorg Med Chem. 2016 Apr 15;24(8):1683-95. doi: 10.1016/j.bmc.2016.02.040. Epub 2016 Mar 2.

13.

Membrane and inhibitor interactions of intracellular phospholipases A2.

Mouchlis VD, Dennis EA.

Adv Biol Regul. 2016 May;61:17-24. doi: 10.1016/j.jbior.2015.11.011. Epub 2015 Dec 19. Review.

14.

Binding sites for interaction of peroxiredoxin 6 with surfactant protein A.

Krishnaiah SY, Dodia C, Sorokina EM, Li H, Feinstein SI, Fisher AB.

Biochim Biophys Acta. 2016 Apr;1864(4):419-25. doi: 10.1016/j.bbapap.2015.12.009. Epub 2015 Dec 23.

15.

Synthesis, Molecular Modeling, and Biological Evaluation of Novel 1, 3-Diphenyl-2-propen-1-one Based Pyrazolines as Anti-inflammatory Agents.

Bukhari SN, Zhang X, Jantan I, Zhu HL, Amjad MW, Masand VH.

Chem Biol Drug Des. 2015 Jun;85(6):729-42. doi: 10.1111/cbdd.12457. Epub 2014 Nov 15.

PMID:
25328063
16.

A structure-based proposal for a comprehensive myotoxic mechanism of phospholipase A2-like proteins from viperid snake venoms.

Fernandes CA, Borges RJ, Lomonte B, Fontes MR.

Biochim Biophys Acta. 2014 Dec;1844(12):2265-76. doi: 10.1016/j.bbapap.2014.09.015. Epub 2014 Sep 30. Review.

PMID:
25278377
17.

The biflavonoid morelloflavone inhibits the enzymatic and biological activities of a snake venom phospholipase A2.

Pereañez JA, Patiño AC, Núñez V, Osorio E.

Chem Biol Interact. 2014 Sep 5;220:94-101. doi: 10.1016/j.cbi.2014.06.015. Epub 2014 Jul 1.

PMID:
24995575
18.

Pyrazolo[3,4-d]pyrimidines as inhibitor of anti-coagulation and inflammation activities of phospholipase A 2 : insight from molecular docking studies.

Yadava U, Singh M, Roychoudhury M.

J Biol Phys. 2013 Jun;39(3):419-38. doi: 10.1007/s10867-013-9299-7. Epub 2013 Feb 23.

19.

Potent inhibition of human 5-lipoxygenase and microsomal prostaglandin E₂ synthase-1 by the anti-carcinogenic and anti-inflammatory agent embelin.

Schaible AM, Traber H, Temml V, Noha SM, Filosa R, Peduto A, Weinigel C, Barz D, Schuster D, Werz O.

Biochem Pharmacol. 2013 Aug 15;86(4):476-86. doi: 10.1016/j.bcp.2013.04.015. Epub 2013 Apr 24.

PMID:
23623753
20.

Evaluation of biotransformed berberine derivatives as anti inflammatory drugs: an in silico study.

Naveen CD, Prasanth GK, Sadasivan C, Haridas M.

Interdiscip Sci. 2012 Dec;4(4):268-72. doi: 10.1007/s12539-012-0142-9. Epub 2013 Jan 26.

PMID:
23354815

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