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Items: 1 to 20 of 67


Sorting cells alters their redox state and cellular metabolome.

Llufrio EM, Wang L, Naser FJ, Patti GJ.

Redox Biol. 2018 Jun;16:381-387. doi: 10.1016/j.redox.2018.03.004. Epub 2018 Mar 9.


Identifying off-target effects of etomoxir reveals that carnitine palmitoyltransferase I is essential for cancer cell proliferation independent of β-oxidation.

Yao CH, Liu GY, Wang R, Moon SH, Gross RW, Patti GJ.

PLoS Biol. 2018 Mar 29;16(3):e2003782. doi: 10.1371/journal.pbio.2003782. eCollection 2018 Mar.


Radioresistant Cervical Cancers Are Sensitive to Inhibition of Glycolysis and Redox Metabolism.

Rashmi R, Huang X, Floberg JM, Elhammali AE, McCormick ML, Patti GJ, Spitz DR, Schwarz JK.

Cancer Res. 2018 Mar 15;78(6):1392-1403. doi: 10.1158/0008-5472.CAN-17-2367. Epub 2018 Jan 16.


Consumption of NADPH for 2-HG Synthesis Increases Pentose Phosphate Pathway Flux and Sensitizes Cells to Oxidative Stress.

Gelman SJ, Naser F, Mahieu NG, McKenzie LD, Dunn GP, Chheda MG, Patti GJ.

Cell Rep. 2018 Jan 9;22(2):512-522. doi: 10.1016/j.celrep.2017.12.050.


Two complementary reversed-phase separations for comprehensive coverage of the semipolar and nonpolar metabolome.

Naser FJ, Mahieu NG, Wang L, Spalding JL, Johnson SL, Patti GJ.

Anal Bioanal Chem. 2018 Feb;410(4):1287-1297. doi: 10.1007/s00216-017-0768-x. Epub 2017 Dec 18.


Systems-Level Annotation of a Metabolomics Data Set Reduces 25 000 Features to Fewer than 1000 Unique Metabolites.

Mahieu NG, Patti GJ.

Anal Chem. 2017 Oct 3;89(19):10397-10406. doi: 10.1021/acs.analchem.7b02380. Epub 2017 Sep 15.


Lactate metabolism is associated with mammalian mitochondria.

Chen YJ, Mahieu NG, Huang X, Singh M, Crawford PA, Johnson SL, Gross RW, Schaefer J, Patti GJ.

Nat Chem Biol. 2016 Nov;12(11):937-943. doi: 10.1038/nchembio.2172. Epub 2016 Sep 12.


Inaccurate quantitation of palmitate in metabolomics and isotope tracer studies due to plastics.

Yao CH, Liu GY, Yang K, Gross RW, Patti GJ.

Metabolomics. 2016 Sep;12. pii: 143. Epub 2016 Aug 8.


Defining and Detecting Complex Peak Relationships in Mass Spectral Data: The Mz.unity Algorithm.

Mahieu NG, Spalding JL, Gelman SJ, Patti GJ.

Anal Chem. 2016 Sep 20;88(18):9037-46. doi: 10.1021/acs.analchem.6b01702. Epub 2016 Aug 31.


Mitochondrial Pyruvate Import Promotes Long-Term Survival of Antibody-Secreting Plasma Cells.

Lam WY, Becker AM, Kennerly KM, Wong R, Curtis JD, Llufrio EM, McCommis KS, Fahrmann J, Pizzato HA, Nunley RM, Lee J, Wolfgang MJ, Patti GJ, Finck BN, Pearce EL, Bhattacharya D.

Immunity. 2016 Jul 19;45(1):60-73. doi: 10.1016/j.immuni.2016.06.011. Epub 2016 Jul 5.


Biomonitoring in the Era of the Exposome.

Dennis KK, Marder E, Balshaw DM, Cui Y, Lynes MA, Patti GJ, Rappaport SM, Shaughnessy DT, Vrijheid M, Barr DB.

Environ Health Perspect. 2017 Apr;125(4):502-510. doi: 10.1289/EHP474. Epub 2016 Jul 6.


Knockdown of triglyceride synthesis does not enhance palmitate lipotoxicity or prevent oleate-mediated rescue in rat hepatocytes.

Leamy AK, Hasenour CM, Egnatchik RA, Trenary IA, Yao CH, Patti GJ, Shiota M, Young JD.

Biochim Biophys Acta. 2016 Sep;1861(9 Pt A):1005-1014. doi: 10.1016/j.bbalip.2016.05.013. Epub 2016 May 29.


Exogenous Fatty Acids Are the Preferred Source of Membrane Lipids in Proliferating Fibroblasts.

Yao CH, Fowle-Grider R, Mahieu NG, Liu GY, Chen YJ, Wang R, Singh M, Potter GS, Gross RW, Schaefer J, Johnson SL, Patti GJ.

Cell Chem Biol. 2016 Apr 21;23(4):483-93. doi: 10.1016/j.chembiol.2016.03.007. Epub 2016 Mar 31.


Profiling cancer metabolism at the 'omic' level: a last resort or the next frontier?

Gelman SJ, Patti GJ.

Cancer Metab. 2016 Mar 21;4:2. doi: 10.1186/s40170-016-0144-x. eCollection 2016. No abstract available.


Bar Coding MS(2) Spectra for Metabolite Identification.

Spalding JL, Cho K, Mahieu NG, Nikolskiy I, Llufrio EM, Johnson SL, Patti GJ.

Anal Chem. 2016 Mar 1;88(5):2538-42. doi: 10.1021/acs.analchem.5b04925. Epub 2016 Feb 11.


A roadmap for the XCMS family of software solutions in metabolomics.

Mahieu NG, Genenbacher JL, Patti GJ.

Curr Opin Chem Biol. 2016 Feb;30:87-93. doi: 10.1016/j.cbpa.2015.11.009. Epub 2015 Dec 11. Review.


Evidence that 2-hydroxyglutarate is not readily metabolized in colorectal carcinoma cells.

Gelman SJ, Mahieu NG, Cho K, Llufrio EM, Wencewicz TA, Patti GJ.

Cancer Metab. 2015 Dec 1;3:13. doi: 10.1186/s40170-015-0139-z. eCollection 2015.


Global metabolomics reveals metabolic dysregulation in ischemic retinopathy.

Paris LP, Johnson CH, Aguilar E, Usui Y, Cho K, Hoang LT, Feitelberg D, Benton HP, Westenskow PD, Kurihara T, Trombley J, Tsubota K, Ueda S, Wakabayashi Y, Patti GJ, Ivanisevic J, Siuzdak G, Friedlander M.

Metabolomics. 2016;12:15. doi: 10.1007/s11306-015-0877-5. Epub 2015 Nov 18.


Thermal Degradation of Small Molecules: A Global Metabolomic Investigation.

Fang M, Ivanisevic J, Benton HP, Johnson CH, Patti GJ, Hoang LT, Uritboonthai W, Kurczy ME, Siuzdak G.

Anal Chem. 2015 Nov 3;87(21):10935-41. doi: 10.1021/acs.analchem.5b03003. Epub 2015 Oct 14.


Warpgroup: increased precision of metabolomic data processing by consensus integration bound analysis.

Mahieu NG, Spalding JL, Patti GJ.

Bioinformatics. 2016 Jan 15;32(2):268-75. doi: 10.1093/bioinformatics/btv564. Epub 2015 Sep 30.

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