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Items: 1 to 20 of 178

1.

Semisynthesis and Inhibitory Effects of Solidagenone Derivatives on TLR-Mediated Inflammatory Responses.

Cuadrado I, Amesty Á, Cedrón JC, Oberti JC, Estévez-Braun A, Hortelano S, Heras BL.

Molecules. 2018 Dec 4;23(12). pii: E3197. doi: 10.3390/molecules23123197.

2.

Nitric oxide inhibitory limonoids as potential anti-neuroinflammatory agents from Swietenia mahagoni.

Shi Z, An L, Yang X, Xi Y, Zhang C, Shuo Y, Zhang J, Jin DQ, Ohizumi Y, Lee D, Xu J, Guo Y.

Bioorg Chem. 2018 Nov 19;84:177-185. doi: 10.1016/j.bioorg.2018.11.012. [Epub ahead of print]

PMID:
30502629
3.

Anti-rheumatoid arthritis effects in adjuvant-induced arthritis in rats and molecular docking studies of Polygonum orientale L. extracts.

Gou KJ, Zeng R, Ren XD, Dou QL, Yang QB, Dong Y, Qu Y.

Immunol Lett. 2018 Sep;201:59-69. doi: 10.1016/j.imlet.2018.11.009. Epub 2018 Nov 22.

PMID:
30471320
4.

Inhibition of PI3K/Akt/NF-κB signaling with leonurine for ameliorating the progression of osteoarthritis: In vitro and in vivo studies.

Hu ZC, Gong LF, Li XB, Fu X, Xuan JW, Feng ZH, Ni WF.

J Cell Physiol. 2018 Nov 11. doi: 10.1002/jcp.27437. [Epub ahead of print]

PMID:
30417459
5.

Functional mechanism of tracheal relaxation, antiasthmatic, and toxicological studies of 6-hydroxyflavone.

Flores-Flores A, Estrada-Soto S, Millán-Pacheco C, Bazán-Perkins B, Villalobos-Molina R, Moreno-Fierros L, Hernández-Pando R, García-Jiménez S, Rivera-Leyva JC.

Drug Dev Res. 2018 Nov 5. doi: 10.1002/ddr.21484. [Epub ahead of print]

PMID:
30394554
6.

Novel neurotoxic peptides from Protopalythoa variabilis virtually interact with voltage-gated sodium channel and display anti-epilepsy and neuroprotective activities in zebrafish.

Liao Q, Li S, Siu SWI, Morlighem JRL, Wong CTT, Wang X, Rádis-Baptista G, Lee SM.

Arch Toxicol. 2018 Oct 17. doi: 10.1007/s00204-018-2334-5. [Epub ahead of print]

PMID:
30334080
7.

Antitumour, Immunomodulatory activity and in silico studies of naphthopyranones targeting iNOS, a relevant target for the treatment of Helicobacter pylori infection.

Ardisson JS, Gonçalves RCR, Rodrigues RP, Kitagawa RR.

Biomed Pharmacother. 2018 Nov;107:1160-1165. doi: 10.1016/j.biopha.2018.08.098. Epub 2018 Aug 28.

PMID:
30257329
8.

Hydroxysafflor yellow A (HSYA) targets the NF-κB and MAPK pathways and ameliorates the development of osteoarthritis.

Hu ZC, Xie ZJ, Tang Q, Li XB, Fu X, Feng ZH, Xuan JW, Ni WF, Wu AM.

Food Funct. 2018 Aug 15;9(8):4443-4456. doi: 10.1039/c8fo00732b.

PMID:
30070297
9.

Synthesis and Structure-Activity Relationships of Tetrahydro-β-carboline Derivatives as Anticancer and Cancer-chemopreventive Agents.

Zhang M, Park EJ, Kondratyuk TP, Pezzuto JM, Sun D.

Anticancer Res. 2018 Aug;38(8):4425-4433. doi: 10.21873/anticanres.12744.

PMID:
30061206
10.

GR24, a synthetic analog of Strigolactones, alleviates inflammation and promotes Nrf2 cytoprotective response: In vitro and in silico evidences.

Tumer TB, Yılmaz B, Ozleyen A, Kurt B, Tok TT, Taskin KM, Kulabas SS.

Comput Biol Chem. 2018 Oct;76:179-190. doi: 10.1016/j.compbiolchem.2018.07.014. Epub 2018 Jul 18.

PMID:
30048925
11.

Bioactivity-Guided Isolation of Anti-Inflammatory Constituents of the Rare Mushroom Calvatia nipponica in LPS-Stimulated RAW264.7 Macrophages.

Lee S, Lee D, Lee JC, Kang KS, Ryoo R, Park HJ, Kim KH.

Chem Biodivers. 2018 Sep;15(9):e1800203. doi: 10.1002/cbdv.201800203. Epub 2018 Jul 29.

PMID:
29933520
12.

Dihydronortanshinone, a natural product, alleviates LPS-induced inflammatory response through NF-κB, mitochondrial ROS, and MAPK pathways.

Wu X, Gao H, Hou Y, Yu J, Sun W, Wang Y, Chen X, Feng Y, Xu QM, Chen X.

Toxicol Appl Pharmacol. 2018 Sep 15;355:1-8. doi: 10.1016/j.taap.2018.06.007. Epub 2018 Jun 12.

PMID:
29906494
13.

α-Terpineol reduces cancer pain via modulation of oxidative stress and inhibition of iNOS.

Gouveia DN, Costa JS, Oliveira MA, Rabelo TK, Silva AMOE, Carvalho AA, Miguel-Dos-Santos R, Lauton-Santos S, Scotti L, Scotti MT, Santos MRVD, Quintans-Júnior LJ, Albuquerque Junior RLC, Guimarães AG.

Biomed Pharmacother. 2018 Sep;105:652-661. doi: 10.1016/j.biopha.2018.06.027. Epub 2018 Jun 11.

PMID:
29902764
14.

Butyrolactone-I from Coral-Derived Fungus Aspergillus terreus Attenuates Neuro-Inflammatory Response via Suppression of NF-κB Pathway in BV-2 Cells.

Zhang YY, Zhang Y, Yao YB, Lei XL, Qian ZJ.

Mar Drugs. 2018 Jun 7;16(6). pii: E202. doi: 10.3390/md16060202.

15.

Design, synthesis and investigation of potential anti-inflammatory activity of O-alkyl and O-benzyl hesperetin derivatives.

Huang AL, Zhang YL, Ding HW, Li B, Huang C, Meng XM, Li J.

Int Immunopharmacol. 2018 Aug;61:82-91. doi: 10.1016/j.intimp.2018.05.009. Epub 2018 May 28.

PMID:
29852476
16.

Genistein: is the multifarious botanical a natural anthelmintic too?

Tandon V, Das B.

J Parasit Dis. 2018 Jun;42(2):151-161. doi: 10.1007/s12639-018-0984-0. Epub 2018 Mar 5.

PMID:
29844617
17.

Biochemical and biophysical insights into the metal binding spectrum and bioactivity of arginase of Entamoeba histolytica.

Malik A, Singh H, Pareek A, Tomar S.

Metallomics. 2018 Apr 25;10(4):623-638. doi: 10.1039/c8mt00002f.

PMID:
29691540
18.

Discovery of N-{3-[(ethanimidoylamino)methyl]benzyl}-l-prolinamide dihydrochloride: A new potent and selective inhibitor of the inducible nitric oxide synthase as a promising agent for the therapy of malignant glioma.

Maccallini C, Di Matteo M, Gallorini M, Montagnani M, Graziani V, Ammazzalorso A, Amoia P, De Filippis B, Di Silvestre S, Fantacuzzi M, Giampietro L, Potenza MA, Re N, Pandolfi A, Cataldi A, Amoroso R.

Eur J Med Chem. 2018 May 25;152:53-64. doi: 10.1016/j.ejmech.2018.04.027. Epub 2018 Apr 13.

PMID:
29689474
19.

Synthesis and biological evaluation of clovamide analogues as potent anti-neuroinflammatory agents in vitro and in vivo.

Hu XL, Lin J, Lv XY, Feng JH, Zhang XQ, Wang H, Ye WC.

Eur J Med Chem. 2018 May 10;151:261-271. doi: 10.1016/j.ejmech.2018.03.081. Epub 2018 Apr 1.

PMID:
29626798
20.

Dystrophin's central domain forms a complex filament that becomes disorganized by in-frame deletions.

Delalande O, Molza AE, Dos Santos Morais R, Chéron A, Pollet É, Raguenes-Nicol C, Tascon C, Giudice E, Guilbaud M, Nicolas A, Bondon A, Leturcq F, Férey N, Baaden M, Perez J, Roblin P, Piétri-Rouxel F, Hubert JF, Czjzek M, Le Rumeur E.

J Biol Chem. 2018 May 4;293(18):6637-6646. doi: 10.1074/jbc.M117.809798. Epub 2018 Mar 13.

PMID:
29535188

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