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Items: 6

1.

Inhibitory properties of 1,4-dideoxy-1,4-imino-d-arabinitol (DAB) derivatives acting on glycogen metabolising enzymes.

Díaz-Lobo M, Concia AL, Gómez L, Clapés P, Fita I, Guinovart JJ, Ferrer JC.

Org Biomol Chem. 2016 Sep 26;14(38):9105-9113.

2.

Sourcing the affinity of flavonoids for the glycogen phosphorylase inhibitor site via crystallography, kinetics and QM/MM-PBSA binding studies: comparison of chrysin and flavopiridol.

Tsitsanou KE, Hayes JM, Keramioti M, Mamais M, Oikonomakos NG, Kato A, Leonidas DD, Zographos SE.

Food Chem Toxicol. 2013 Nov;61:14-27. doi: 10.1016/j.fct.2012.12.030. Epub 2012 Dec 29.

PMID:
23279842
3.

N-(4-Substituted-benzoyl)-N'-(β-d-glucopyranosyl)ureas as inhibitors of glycogen phosphorylase: Synthesis and evaluation by kinetic, crystallographic, and molecular modelling methods.

Nagy V, Felföldi N, Kónya B, Praly JP, Docsa T, Gergely P, Chrysina ED, Tiraidis C, Kosmopoulou MN, Alexacou KM, Konstantakaki M, Leonidas DD, Zographos SE, Oikonomakos NG, Kozmon S, Tvaroška I, Somsák L.

Bioorg Med Chem. 2012 Mar 1;20(5):1801-16. doi: 10.1016/j.bmc.2011.12.059. Epub 2012 Jan 20.

PMID:
22325154
4.

1-(3-Deoxy-3-fluoro-beta-d-glucopyranosyl) pyrimidine derivatives as inhibitors of glycogen phosphorylase b: Kinetic, crystallographic and modelling studies.

Tsirkone VG, Tsoukala E, Lamprakis C, Manta S, Hayes JM, Skamnaki VT, Drakou C, Zographos SE, Komiotis D, Leonidas DD.

Bioorg Med Chem. 2010 May 15;18(10):3413-25. doi: 10.1016/j.bmc.2010.04.004. Epub 2010 Apr 7.

PMID:
20430629
5.

Glucose-based spiro-isoxazolines: a new family of potent glycogen phosphorylase inhibitors.

Benltifa M, Hayes JM, Vidal S, Gueyrard D, Goekjian PG, Praly JP, Kizilis G, Tiraidis C, Alexacou KM, Chrysina ED, Zographos SE, Leonidas DD, Archontis G, Oikonomakos NG.

Bioorg Med Chem. 2009 Oct 15;17(20):7368-80. doi: 10.1016/j.bmc.2009.08.060. Epub 2009 Sep 2.

PMID:
19781947
6.

Modeling aided design of potent glycogen phosphorylase inhibitors.

Deng Q, Lu Z, Bohn J, Ellsworth KP, Myers RW, Geissler WM, Harris G, Willoughby CA, Chapman K, McKeever B, Mosley R.

J Mol Graph Model. 2005 Apr;23(5):457-64.

PMID:
15781188

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