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Items: 1 to 20 of 54


Alteration of human macrophage phenotypes by the anti-fibrotic drug nintedanib.

Bellamri N, Morzadec C, Joannes A, Lecureur V, Wollin L, Jouneau S, Vernhet L.

Int Immunopharmacol. 2019 Apr 8;72:112-123. doi: 10.1016/j.intimp.2019.03.061. [Epub ahead of print]


Induction of multidrug resistance-associated protein 3 expression by diesel exhaust particle extract in human bronchial epithelial BEAS-2B cells.

Le Vée M, Bacle A, Jouan E, Lecureur V, Potin S, Fardel O.

Toxicol In Vitro. 2019 Mar 19;58:60-68. doi: 10.1016/j.tiv.2019.03.021. [Epub ahead of print]


An integrated functional and transcriptomic analysis reveals that repeated exposure to diesel exhaust induces sustained mitochondrial and cardiac dysfunctions.

Karoui A, Crochemore C, Mulder P, Preterre D, Cazier F, Dewaele D, Corbière C, Mekki M, Vendeville C, Richard V, Vaugeois JM, Fardel O, Sichel F, Lecureur V, Monteil C.

Environ Pollut. 2019 Mar;246:518-526. doi: 10.1016/j.envpol.2018.12.049. Epub 2018 Dec 17.


A novel Staphylococcus aureus cis-trans type I toxin-antitoxin module with dual effects on bacteria and host cells.

Germain-Amiot N, Augagneur Y, Camberlein E, Nicolas I, Lecureur V, Rouillon A, Felden B.

Nucleic Acids Res. 2019 Feb 28;47(4):1759-1773. doi: 10.1093/nar/gky1257.


Efferocytosis capacities of blood monocyte-derived macrophages in systemic sclerosis.

Ballerie A, Lescoat A, Augagneur Y, Lelong M, Morzadec C, Cazalets C, Jouneau S, Fardel O, Vernhet L, Jégo P, Lecureur V.

Immunol Cell Biol. 2019 Mar;97(3):340-347. doi: 10.1111/imcb.12217. Epub 2018 Dec 13.


M1/M2 polarisation state of M-CSF blood-derived macrophages in systemic sclerosis.

Lescoat A, Ballerie A, Jouneau S, Fardel O, Vernhet L, Jego P, Lecureur V.

Ann Rheum Dis. 2018 Sep 29. pii: annrheumdis-2018-214333. doi: 10.1136/annrheumdis-2018-214333. [Epub ahead of print] No abstract available.


Long term exposure to environmental concentrations of diesel exhaust particles does not impact the phenotype of human bronchial epithelial cells.

Savary CC, Bellamri N, Morzadec C, Langouët S, Lecureur V, Vernhet L.

Toxicol In Vitro. 2018 Oct;52:154-160. doi: 10.1016/j.tiv.2018.06.014. Epub 2018 Jun 19.


Distinct Properties of Human M-CSF and GM-CSF Monocyte-Derived Macrophages to Simulate Pathological Lung Conditions In Vitro: Application to Systemic and Inflammatory Disorders with Pulmonary Involvement.

Lescoat A, Ballerie A, Augagneur Y, Morzadec C, Vernhet L, Fardel O, Jégo P, Jouneau S, Lecureur V.

Int J Mol Sci. 2018 Mar 17;19(3). pii: E894. doi: 10.3390/ijms19030894.


M-CSF and GM-CSF monocyte-derived macrophages in systemic sclerosis: the two sides of the same coin?

Lescoat A, Jégo P, Lecureur V.

Ann Rheum Dis. 2019 Mar;78(3):e19. doi: 10.1136/annrheumdis-2018-213112. Epub 2018 Feb 9. No abstract available.


Comparative study of diesel and biodiesel exhausts on lung oxidative stress and genotoxicity in rats.

Douki T, Corbière C, Preterre D, Martin PJ, Lecureur V, André V, Landkocz Y, Pottier I, Keravec V, Fardel O, Moreira-Rebelo S, Pottier D, Vendeville C, Dionnet F, Gosset P, Billet S, Monteil C, Sichel F.

Environ Pollut. 2018 Apr;235:514-524. doi: 10.1016/j.envpol.2017.12.077. Epub 2018 Jan 8.


Repression of interferon β-regulated cytokines by the JAK1/2 inhibitor ruxolitinib in inflammatory human macrophages.

Febvre-James M, Lecureur V, Augagneur Y, Mayati A, Fardel O.

Int Immunopharmacol. 2018 Jan;54:354-365. doi: 10.1016/j.intimp.2017.11.032. Epub 2017 Dec 1.


Granulometry, microbial composition and biological activity of dusts collected in French dairy farms.

Pfister H, Morzadec C, Le Cann P, Madec L, Lecureur V, Chouvet M, Jouneau S, Vernhet L.

Environ Res. 2017 Oct;158:691-702. doi: 10.1016/j.envres.2017.07.025. Epub 2017 Jul 20.


CD16-positive circulating monocytes and fibrotic manifestations of systemic sclerosis.

Lescoat A, Lecureur V, Roussel M, Sunnaram BL, Ballerie A, Coiffier G, Jouneau S, Fardel O, Fest T, Jégo P.

Clin Rheumatol. 2017 Jul;36(7):1649-1654. doi: 10.1007/s10067-017-3597-6. Epub 2017 Mar 14.


Aryl hydrocarbon receptor-dependent up-regulation of the heterodimeric amino acid transporter LAT1 (SLC7A5)/CD98hc (SLC3A2) by diesel exhaust particle extract in human bronchial epithelial cells.

Le Vee M, Jouan E, Lecureur V, Fardel O.

Toxicol Appl Pharmacol. 2016 Jan 1;290:74-85. doi: 10.1016/j.taap.2015.11.014. Epub 2015 Nov 24.


AhR-dependent secretion of PDGF-BB by human classically activated macrophages exposed to DEP extracts stimulates lung fibroblast proliferation.

Jaguin M, Fardel O, Lecureur V.

Toxicol Appl Pharmacol. 2015 Jun 15;285(3):170-8. doi: 10.1016/j.taap.2015.04.007. Epub 2015 Apr 17.


Regulation of human hepatic drug transporter activity and expression by diesel exhaust particle extract.

Le Vee M, Jouan E, Stieger B, Lecureur V, Fardel O.

PLoS One. 2015 Mar 24;10(3):e0121232. doi: 10.1371/journal.pone.0121232. eCollection 2015.


Exposure to diesel exhaust particle extracts (DEPe) impairs some polarization markers and functions of human macrophages through activation of AhR and Nrf2.

Jaguin M, Fardel O, Lecureur V.

PLoS One. 2015 Feb 24;10(2):e0116560. doi: 10.1371/journal.pone.0116560. eCollection 2015.


AhR and Arnt differentially regulate NF-κB signaling and chemokine responses in human bronchial epithelial cells.

Øvrevik J, Låg M, Lecureur V, Gilot D, Lagadic-Gossmann D, Refsnes M, Schwarze PE, Skuland T, Becher R, Holme JA.

Cell Commun Signal. 2014 Jul 24;12:48. doi: 10.1186/s12964-014-0048-8.


Impaired functions of macrophage from cystic fibrosis patients: CD11b, TLR-5 decrease and sCD14, inflammatory cytokines increase.

Simonin-Le Jeune K, Le Jeune A, Jouneau S, Belleguic C, Roux PF, Jaguin M, Dimanche-Boitre MT, Lecureur V, Leclercq C, Desrues B, Brinchault G, Gangneux JP, Martin-Chouly C.

PLoS One. 2013 Sep 30;8(9):e75667. doi: 10.1371/journal.pone.0075667. eCollection 2013.


Polarization profiles of human M-CSF-generated macrophages and comparison of M1-markers in classically activated macrophages from GM-CSF and M-CSF origin.

Jaguin M, Houlbert N, Fardel O, Lecureur V.

Cell Immunol. 2013 Jan;281(1):51-61. doi: 10.1016/j.cellimm.2013.01.010. Epub 2013 Feb 4.


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