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Items: 1 to 20 of 40

1.

Ophthalmic acid as a read-out for hepatic glutathione metabolism in humans.

Kim Mc van M, Dello SA, de Jong MC, van Eijk HM, de Kok TM, Briedé JJ, Schaap FG, Damink SWO, Dejong CH.

J Clin Transl Res. 2018 Mar 25;3(Suppl 2):366-374. eCollection 2018 Jul 30.

2.

Improved Preventive Effects of Combined Bioactive Compounds Present in Different Blueberry Varieties as Compared to Single Phytochemicals.

van Breda SGJ, Briedé JJ, de Kok TMCM.

Nutrients. 2018 Dec 29;11(1). pii: E61. doi: 10.3390/nu11010061.

3.

Persistence of Epigenomic Effects After Recovery From Repeated Treatment With Two Nephrocarcinogens.

Limonciel A, van Breda SG, Jiang X, Tredwell GD, Wilmes A, Aschauer L, Siskos AP, Sachinidis A, Keun HC, Kopp-Schneider A, de Kok TM, Kleinjans JCS, Jennings P.

Front Genet. 2018 Dec 3;9:558. doi: 10.3389/fgene.2018.00558. eCollection 2018.

4.

Embracing the Dark Side: Computational Approaches to Unveil the Functionality of Genes Lacking Biological Annotation in Drug-Induced Liver Injury.

Souza T, Trairatphisan P, Piñero J, Furlong LI, Saez-Rodriguez J, Kleinjans J, Jennen D.

Front Genet. 2018 Nov 20;9:527. doi: 10.3389/fgene.2018.00527. eCollection 2018.

5.

Interethnic analyses of blood pressure loci in populations of East Asian and European descent.

Takeuchi F, Akiyama M, Matoba N, Katsuya T, Nakatochi M, Tabara Y, Narita A, Saw WY, Moon S, Spracklen CN, Chai JF, Kim YJ, Zhang L, Wang C, Li H, Li H, Wu JY, Dorajoo R, Nierenberg JL, Wang YX, He J, Bennett DA, Takahashi A, Momozawa Y, Hirata M, Matsuda K, Rakugi H, Nakashima E, Isono M, Shirota M, Hozawa A, Ichihara S, Matsubara T, Yamamoto K, Kohara K, Igase M, Han S, Gordon-Larsen P, Huang W, Lee NR, Adair LS, Hwang MY, Lee J, Chee ML, Sabanayagam C, Zhao W, Liu J, Reilly DF, Sun L, Huo S, Edwards TL, Long J, Chang LC, Chen CH, Yuan JM, Koh WP, Friedlander Y, Kelly TN, Bin Wei W, Xu L, Cai H, Xiang YB, Lin K, Clarke R, Walters RG, Millwood IY, Li L, Chambers JC, Kooner JS, Elliott P, van der Harst P; International Genomics of Blood Pressure (iGEN-BP) Consortium, Chen Z, Sasaki M, Shu XO, Jonas JB, He J, Heng CK, Chen YT, Zheng W, Lin X, Teo YY, Tai ES, Cheng CY, Wong TY, Sim X, Mohlke KL, Yamamoto M, Kim BJ, Miki T, Nabika T, Yokota M, Kamatani Y, Kubo M, Kato N.

Nat Commun. 2018 Nov 28;9(1):5052. doi: 10.1038/s41467-018-07345-0.

6.

RATEmiRs: the rat atlas of tissue-specific and enriched miRNAs database.

Bushel PR, Caiment F, Wu H, O'Lone R, Day F, Calley J, Smith A, Li J.

BMC Genomics. 2018 Nov 19;19(1):825. doi: 10.1186/s12864-018-5220-x.

7.

Phosphorylation of eIF2α promotes cell survival in response to benzo[a]pyrene exposure.

Smit E, Kleinjans JCS, van den Beucken T.

Toxicol In Vitro. 2019 Feb;54:330-337. doi: 10.1016/j.tiv.2018.10.015. Epub 2018 Oct 29.

8.

Profiling Cellular Processes in Adipose Tissue during Weight Loss Using Time Series Gene Expression.

Tareen SHK, Adriaens ME, Arts ICW, de Kok TM, Vink RG, Roumans NJT, van Baak MA, Mariman ECM, Evelo CT, Kutmon M.

Genes (Basel). 2018 Oct 29;9(11). pii: E525. doi: 10.3390/genes9110525.

9.

Mapping Air Pollution with Google Street View Cars: Efficient Approaches with Mobile Monitoring and Land Use Regression.

Messier KP, Chambliss SE, Gani S, Alvarez R, Brauer M, Choi JJ, Hamburg SP, Kerckhoffs J, LaFranchi B, Lunden MM, Marshall JD, Portier CJ, Roy A, Szpiro AA, Vermeulen RCH, Apte JS.

Environ Sci Technol. 2018 Oct 24. doi: 10.1021/acs.est.8b03395. [Epub ahead of print]

10.

Oxidative stress in healthy pregnancy and preeclampsia is linked to chronic inflammation, iron status and vascular function.

Mannaerts D, Faes E, Cos P, Briedé JJ, Gyselaers W, Cornette J, Gorbanev Y, Bogaerts A, Spaanderman M, Van Craenenbroeck E, Jacquemyn Y.

PLoS One. 2018 Sep 11;13(9):e0202919. doi: 10.1371/journal.pone.0202919. eCollection 2018.

11.

Comparison of statistical methods and the use of quality control samples for batch effect correction in human transcriptome data.

Espín-Pérez A, Portier C, Chadeau-Hyam M, van Veldhoven K, Kleinjans JCS, de Kok TMCM.

PLoS One. 2018 Aug 30;13(8):e0202947. doi: 10.1371/journal.pone.0202947. eCollection 2018.

12.

Titanium dioxide food additive (E171) induces ROS formation and genotoxicity: contribution of micro and nano-sized fractions.

Proquin H, Rodríguez-Ibarra C, Moonen C, Urrutia Ortega IM, Briedé JJ, de Kok TM, van Loveren H, Irasema Chirino Y.

Mutagenesis. 2018 Sep 17;33(3):267-268. doi: 10.1093/mutage/gey011. No abstract available.

PMID:
30107553
13.

Acute changes in DNA methylation in relation to 24 h personal air pollution exposure measurements: A panel study in four European countries.

Mostafavi N, Vermeulen R, Ghantous A, Hoek G, Probst-Hensch N, Herceg Z, Tarallo S, Naccarati A, Kleinjans JCS, Imboden M, Jeong A, Morley D, Amaral AFS, van Nunen E, Gulliver J, Chadeau-Hyam M, Vineis P, Vlaanderen J.

Environ Int. 2018 Nov;120:11-21. doi: 10.1016/j.envint.2018.07.026. Epub 2018 Jul 25.

PMID:
30055357
14.

Drinking Water Nitrate and Human Health: An Updated Review.

Ward MH, Jones RR, Brender JD, de Kok TM, Weyer PJ, Nolan BT, Villanueva CM, van Breda SG.

Int J Environ Res Public Health. 2018 Jul 23;15(7). pii: E1557. doi: 10.3390/ijerph15071557. Review.

15.

Association between low-grade inflammation and Breast cancer and B-cell Myeloma and Non-Hodgkin Lymphoma: findings from two prospective cohorts.

Berger E, Delpierre C, Hosnijeh FS, Kelly-Irving M, Portengen L, Bergdahl IA, Johansson AS, Krogh V, Palli D, Panico S, Sacerdote C, Tumino R, Kyrtopoulos SA, Vineis P, Chadeau-Hyam M, Vermeulen R, Castagné R; EnviroGenoMarkers.

Sci Rep. 2018 Jul 17;8(1):10805. doi: 10.1038/s41598-018-29041-1.

16.

Exploring the cellular network of metabolic flexibility in the adipose tissue.

Tareen SHK, Kutmon M, Adriaens ME, Mariman ECM, de Kok TM, Arts ICW, Evelo CT.

Genes Nutr. 2018 Jul 5;13:17. doi: 10.1186/s12263-018-0609-3. eCollection 2018. Review.

17.

Short-term transcriptome and microRNAs responses to exposure to different air pollutants in two population studies.

Espín-Pérez A, Krauskopf J, Chadeau-Hyam M, van Veldhoven K, Chung F, Cullinan P, Piepers J, van Herwijnen M, Kubesch N, Carrasco-Turigas G, Nieuwenhuijsen M, Vineis P, Kleinjans JCS, de Kok TMCM.

Environ Pollut. 2018 Nov;242(Pt A):182-190. doi: 10.1016/j.envpol.2018.06.051. Epub 2018 Jun 20.

PMID:
29980036
18.

Transcriptomics analysis reveals new insights in E171-induced molecular alterations in a mouse model of colon cancer.

Proquin H, Jetten MJ, Jonkhout MCM, Garduño-Balderas LG, Briedé JJ, de Kok TM, van Loveren H, Chirino YI.

Sci Rep. 2018 Jun 27;8(1):9738. doi: 10.1038/s41598-018-28063-z.

19.

Translational regulation is a key determinant of the cellular response to benzo[a]pyrene.

Smit E, Caiment F, Piepers J, Kleinjans JCS, van den Beucken T.

Toxicol Lett. 2018 Oct 1;295:144-152. doi: 10.1016/j.toxlet.2018.06.009. Epub 2018 Jun 12.

PMID:
29906497
20.

Bringing in vitro analysis closer to in vivo: Studying doxorubicin toxicity and associated mechanisms in 3D human microtissues with PBPK-based dose modelling.

Verheijen M, Schrooders Y, Gmuender H, Nudischer R, Clayton O, Hynes J, Niederer S, Cordes H, Kuepfer L, Kleinjans J, Caiment F.

Toxicol Lett. 2018 Sep 15;294:184-192. doi: 10.1016/j.toxlet.2018.05.029. Epub 2018 May 24.

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