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Items: 1 to 20 of 89

1.

Identification and development of benzoxazole derivatives as novel bacterial glutamate racemase inhibitors.

Malapati P, Krishna VS, Nallangi R, Srilakshmi RR, Sriram D.

Eur J Med Chem. 2018 Feb 10;145:23-34. doi: 10.1016/j.ejmech.2017.12.088. Epub 2017 Dec 30.

PMID:
29310027
2.

Ziram inhibits aromatase activity in human placenta and JEG-3 cell line.

Chen L, Chen X, Chen X, Hu Z, Li X, Su Y, Li X, Ge RS.

Steroids. 2017 Dec;128:114-119. doi: 10.1016/j.steroids.2017.09.006. Epub 2017 Sep 23.

PMID:
28951168
3.

RPE65 has an additional function as the lutein to meso-zeaxanthin isomerase in the vertebrate eye.

Shyam R, Gorusupudi A, Nelson K, Horvath MP, Bernstein PS.

Proc Natl Acad Sci U S A. 2017 Oct 10;114(41):10882-10887. doi: 10.1073/pnas.1706332114. Epub 2017 Sep 5.

4.

In silico identification of inhibitors of ribose 5-phosphate isomerase from Trypanosoma cruzi using ligand and structure based approaches.

de V C Sinatti V, R Baptista LP, Alves-Ferreira M, Dardenne L, Hermínio Martins da Silva J, Guimarães AC.

J Mol Graph Model. 2017 Oct;77:168-180. doi: 10.1016/j.jmgm.2017.08.007. Epub 2017 Aug 12.

PMID:
28865321
5.

The antibacterial prodrug activator Rv2466c is a mycothiol-dependent reductase in the oxidative stress response of Mycobacterium tuberculosis.

Rosado LA, Wahni K, Degiacomi G, Pedre B, Young D, de la Rubia AG, Boldrin F, Martens E, Marcos-Pascual L, Sancho-Vaello E, Albesa-Jové D, Provvedi R, Martin C, Makarov V, Versées W, Verniest G, Guerin ME, Mateos LM, Manganelli R, Messens J.

J Biol Chem. 2017 Aug 11;292(32):13097-13110. doi: 10.1074/jbc.M117.797837. Epub 2017 Jun 15.

6.

HPW-RX40 prevents human platelet activation by attenuating cell surface protein disulfide isomerases.

Kung PH, Hsieh PW, Lin YT, Lee JH, Chen IH, Wu CC.

Redox Biol. 2017 Oct;13:266-277. doi: 10.1016/j.redox.2017.05.019. Epub 2017 May 29.

7.

Rational Design of Bacillus coagulans NL01 l-Arabinose Isomerase and Use of Its F279I Variant in d-Tagatose Production.

Zheng Z, Mei W, Xia M, He Q, Ouyang J.

J Agric Food Chem. 2017 Jun 14;65(23):4715-4721. doi: 10.1021/acs.jafc.7b01709. Epub 2017 May 30.

PMID:
28530095
8.

Selective Inhibition of Escherichia coli RNA and DNA Topoisomerase I by Hoechst 33258 Derived Mono- and Bisbenzimidazoles.

Ranjan N, Story S, Fulcrand G, Leng F, Ahmad M, King A, Sur S, Wang W, Tse-Dinh YC, Arya DP.

J Med Chem. 2017 Jun 22;60(12):4904-4922. doi: 10.1021/acs.jmedchem.7b00191. Epub 2017 May 31.

PMID:
28513176
9.

Function of a thermophilic archaeal chaperonin is enhanced by electrostatic interactions with its targets.

Gao L, Hidese R, Fujiwara S.

J Biosci Bioeng. 2017 Sep;124(3):283-288. doi: 10.1016/j.jbiosc.2017.04.008. Epub 2017 May 8.

PMID:
28495561
10.

Antimicrobial mechanism of epigallocatechin gallate and gallocatechin gallate: They target 1-deoxy-d-xylulose 5-phosphate reductoisomerase, the key enzyme of the MEP terpenoid biosynthetic pathway.

Hui X, Hua SH, Wu QQ, Li H, Gao WY.

Arch Biochem Biophys. 2017 May 15;622:1-8. doi: 10.1016/j.abb.2017.04.007. Epub 2017 Apr 18.

PMID:
28428039
11.

Fragment library screening identifies hits that bind to the non-catalytic surface of Pseudomonas aeruginosa DsbA1.

Mohanty B, Rimmer K, McMahon RM, Headey SJ, Vazirani M, Shouldice SR, Coinçon M, Tay S, Morton CJ, Simpson JS, Martin JL, Scanlon MJ.

PLoS One. 2017 Mar 27;12(3):e0173436. doi: 10.1371/journal.pone.0173436. eCollection 2017.

12.

Disulfide isomerase-like protein AtPDIL1-2 is a good candidate for trichlorophenol phytodetoxification.

Peng RH, Qiu J, Tian YS, Gao JJ, Han HJ, Fu XY, Zhu B, Xu J, Wang B, Li ZJ, Wang LJ, Yao QH.

Sci Rep. 2017 Jan 6;7:40130. doi: 10.1038/srep40130.

13.

Kemp Eliminase Activity of Ketosteroid Isomerase.

Lamba V, Sanchez E, Fanning LR, Howe K, Alvarez MA, Herschlag D, Forconi M.

Biochemistry. 2017 Jan 31;56(4):582-591. doi: 10.1021/acs.biochem.6b00762. Epub 2017 Jan 20.

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16.

In silico identification of promiscuous scaffolds as potential inhibitors of 1-deoxy-d-xylulose 5-phosphate reductoisomerase for treatment of Falciparum malaria.

Wadood A, Ghufran M, Hassan SF, Khan H, Azam SS, Rashid U.

Pharm Biol. 2017 Dec;55(1):19-32. Epub 2016 Sep 21.

PMID:
27650666
17.

Characterization of an L-arabinose isomerase from Bacillus coagulans NL01 and its application for D-tagatose production.

Mei W, Wang L, Zang Y, Zheng Z, Ouyang J.

BMC Biotechnol. 2016 Jun 30;16(1):55. doi: 10.1186/s12896-016-0286-5.

18.

FRET-Protease-Coupled Peptidyl-Prolyl cis-trans Isomerase Assay: New Internally Quenched Fluorogenic Substrates for High-Throughput Screening.

Caporale A, Mascanzoni F, Farina B, Sturlese M, Di Sorbo G, Fattorusso R, Ruvo M, Doti N.

J Biomol Screen. 2016 Aug;21(7):701-12. doi: 10.1177/1087057116650402. Epub 2016 May 16.

PMID:
27185744
19.

Cloning, purification, and characterization of xylose isomerase from Thermotoga naphthophila RKU-10.

Fatima B, Aftab MN, Haq IU.

J Basic Microbiol. 2016 Sep;56(9):949-62. doi: 10.1002/jobm.201500589. Epub 2016 Apr 26.

PMID:
27112133
20.

Mutational and Structural Analysis of Conserved Residues in Ribose-5-Phosphate Isomerase B from Leishmania donovani: Role in Substrate Recognition and Conformational Stability.

Kaur PK, Tripathi N, Desale J, Neelagiri S, Yadav S, Bharatam PV, Singh S.

PLoS One. 2016 Mar 8;11(3):e0150764. doi: 10.1371/journal.pone.0150764. eCollection 2016.

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