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Best matches for "Enzyme Crystal Structure Trna Tuberculosis":

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Items: 20

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1.

Thienopyrimidinone Derivatives That Inhibit Bacterial tRNA (Guanine37-N1)-Methyltransferase (TrmD) by Restructuring the Active Site with a Tyrosine-Flipping Mechanism.

Zhong W, Pasunooti KK, Balamkundu S, Wong YH, Nah Q, Gadi V, Gnanakalai S, Chionh YH, McBee ME, Gopal P, Lim SH, Olivier N, Buurman ET, Dick T, Liu CF, Lescar J, Dedon PC.

J Med Chem. 2019 Sep 12;62(17):7788-7805. doi: 10.1021/acs.jmedchem.9b00582. Epub 2019 Aug 29.

2.

Structural and dynamic studies provide insights into specificity and allosteric regulation of ribonuclease as, a key enzyme in mycobacterial virulence.

Calvanese L, Squeglia F, Romano M, D'Auria G, Falcigno L, Berisio R.

J Biomol Struct Dyn. 2019 Jul 22:1-13. doi: 10.1080/07391102.2019.1643786. [Epub ahead of print]

PMID:
31299874
3.

Acylated sulfonamide adenosines as potent inhibitors of the adenylate-forming enzyme superfamily.

De Ruysscher D, Pang L, De Graef S, Nautiyal M, De Borggraeve WM, Rozenski J, Strelkov SV, Weeks SD, Van Aerschot A.

Eur J Med Chem. 2019 Jul 15;174:252-264. doi: 10.1016/j.ejmech.2019.04.045. Epub 2019 Apr 17.

PMID:
31048140
4.

The crystal structure of the drug target Mycobacterium tuberculosis methionyl-tRNA synthetase in complex with a catalytic intermediate.

Barros-Álvarez X, Turley S, Ranade RM, Gillespie JR, Duster NA, Verlinde CLMJ, Fan E, Buckner FS, Hol WGJ.

Acta Crystallogr F Struct Biol Commun. 2018 Apr 1;74(Pt 4):245-254. doi: 10.1107/S2053230X18003151. Epub 2018 Mar 28.

5.

Structures of the Catalytic Domain of Bacterial Primase DnaG in Complexes with DNA Provide Insight into Key Priming Events.

Hou C, Biswas T, Tsodikov OV.

Biochemistry. 2018 Apr 10;57(14):2084-2093. doi: 10.1021/acs.biochem.8b00036. Epub 2018 Mar 23.

PMID:
29558114
6.

Structure of the MazF-mt9 toxin, a tRNA-specific endonuclease from Mycobacterium tuberculosis.

Chen R, Tu J, Liu Z, Meng F, Ma P, Ding Z, Yang C, Chen L, Deng X, Xie W.

Biochem Biophys Res Commun. 2017 May 6;486(3):804-810. doi: 10.1016/j.bbrc.2017.03.132. Epub 2017 Mar 25.

PMID:
28351618
7.

The structure and function of Mycobacterium tuberculosis MazF-mt6 toxin provide insights into conserved features of MazF endonucleases.

Hoffer ED, Miles SJ, Dunham CM.

J Biol Chem. 2017 May 12;292(19):7718-7726. doi: 10.1074/jbc.M117.779306. Epub 2017 Mar 15.

8.

Structural characterization of peptidyl-tRNA hydrolase from Mycobacterium smegmatis by NMR spectroscopy.

Kabra A, Fatma F, Shahid S, Pathak PP, Yadav R, Pulavarti SV, Tripathi S, Jain A, Arora A.

Biochim Biophys Acta. 2016 Oct;1864(10):1304-14. doi: 10.1016/j.bbapap.2016.06.013. Epub 2016 Jul 2.

PMID:
27378575
9.

Biochemical and structural characterization of mycobacterial aspartyl-tRNA synthetase AspS, a promising TB drug target.

Gurcha SS, Usha V, Cox JA, Fütterer K, Abrahams KA, Bhatt A, Alderwick LJ, Reynolds RC, Loman NJ, Nataraj V, Alemparte C, Barros D, Lloyd AJ, Ballell L, Hobrath JV, Besra GS.

PLoS One. 2014 Nov 19;9(11):e113568. doi: 10.1371/journal.pone.0113568. eCollection 2014.

10.

Crystal structure of peptidyl-tRNA hydrolase from mycobacterium smegmatis reveals novel features related to enzyme dynamics.

Kumar A, Singh N, Yadav R, Kumar RP, Sharma S, Arora A, Singh TP.

Int J Biochem Mol Biol. 2012;3(1):58-69. Epub 2012 Feb 15.

11.

Structures of new crystal forms of Mycobacterium tuberculosis peptidyl-tRNA hydrolase and functionally important plasticity of the molecule.

Selvaraj M, Ahmad R, Varshney U, Vijayan M.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Feb 1;68(Pt 2):124-8. doi: 10.1107/S1744309111052341. Epub 2012 Jan 21.

12.

Structural basis for nonribosomal peptide synthesis by an aminoacyl-tRNA synthetase paralog.

Bonnefond L, Arai T, Sakaguchi Y, Suzuki T, Ishitani R, Nureki O.

Proc Natl Acad Sci U S A. 2011 Mar 8;108(10):3912-7. doi: 10.1073/pnas.1019480108. Epub 2011 Feb 15.

13.

Structure of Mycobacterium tuberculosis Rv2714, a representative of a duplicated gene family in Actinobacteria.

Graña M, Bellinzoni M, Miras I, Fiez-Vandal C, Haouz A, Shepard W, Buschiazzo A, Alzari PM.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Oct 1;65(Pt 10):972-7. doi: 10.1107/S1744309109035027. Epub 2009 Sep 18.

14.

Crystal structure of Thermus thermophilus tRNA m1A58 methyltransferase and biophysical characterization of its interaction with tRNA.

Barraud P, Golinelli-Pimpaneau B, Atmanene C, Sanglier S, Van Dorsselaer A, Droogmans L, Dardel F, Tisné C.

J Mol Biol. 2008 Mar 21;377(2):535-50. doi: 10.1016/j.jmb.2008.01.041. Epub 2008 Jan 26.

15.

Conserved amino acids in each subunit of the heteroligomeric tRNA m1A58 Mtase from Saccharomyces cerevisiae contribute to tRNA binding.

Ozanick SG, Bujnicki JM, Sem DS, Anderson JT.

Nucleic Acids Res. 2007;35(20):6808-19. Epub 2007 Oct 10.

16.

Structural plasticity and enzyme action: crystal structures of mycobacterium tuberculosis peptidyl-tRNA hydrolase.

Selvaraj M, Roy S, Singh NS, Sangeetha R, Varshney U, Vijayan M.

J Mol Biol. 2007 Sep 7;372(1):186-93. Epub 2007 Jun 27.

PMID:
17619020
17.
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19.

Cloning and characterization of tRNA (m1A58) methyltransferase (TrmI) from Thermus thermophilus HB27, a protein required for cell growth at extreme temperatures.

Droogmans L, Roovers M, Bujnicki JM, Tricot C, Hartsch T, Stalon V, Grosjean H.

Nucleic Acids Res. 2003 Apr 15;31(8):2148-56.

20.

Crystal structure of Rv2118c: an AdoMet-dependent methyltransferase from Mycobacterium tuberculosis H37Rv.

Gupta A, Kumar PH, Dineshkumar TK, Varshney U, Subramanya HS.

J Mol Biol. 2001 Sep 14;312(2):381-91.

PMID:
11554794

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