Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 12

1.

C-glycosyl flavone from Urginea indica inhibits proliferation & angiogenesis & induces apoptosis via cyclin-dependent kinase 6 in human breast, hepatic & colon cancer cell lines.

Bevara GB, Naveen Kumar AD, Koteshwaramma KL, Badana A, Kumari S, Malla RR.

Indian J Med Res. 2018 Feb;147(2):158-168. doi: 10.4103/ijmr.IJMR_51_16.

2.

Voruciclib, a Potent CDK4/6 Inhibitor, Antagonizes ABCB1 and ABCG2-Mediated Multi-Drug Resistance in Cancer Cells.

Gupta P, Zhang YK, Zhang XY, Wang YJ, Lu KW, Hall T, Peng R, Yang DH, Xie N, Chen ZS.

Cell Physiol Biochem. 2018;45(4):1515-1528. doi: 10.1159/000487578. Epub 2018 Feb 19.

3.

Reduced state transition barrier of CDK6 from open to closed state induced by Thr177 phosphorylation and its implication in binding modes of inhibitors.

He H, Xu J, Xie W, Guo QL, Jiang FL, Liu Y.

Biochim Biophys Acta. 2018 Mar;1862(3):501-512. doi: 10.1016/j.bbagen.2017.11.001. Epub 2017 Nov 3.

PMID:
29108955
4.

Discovery of a class of diheteroaromatic amines as orally bioavailable CDK1/4/6 inhibitors.

Fu Y, Tang S, Su Y, Lan X, Ye Y, Zha C, Li L, Cao J, Chen Y, Jiang L, Huang Y, Ding J, Geng M, Huang M, Wan H.

Bioorg Med Chem Lett. 2017 Dec 1;27(23):5332-5336. doi: 10.1016/j.bmcl.2017.09.050. Epub 2017 Oct 16.

PMID:
29074254
5.

Curcumin: Synthesis optimization and in silico interaction with cyclin dependent kinase.

Ahmed M, Abdul Qadir M, Imtiaz Shafiq M, Muddassar M, Hameed A, Nadeem Arshad M, Asiri AM.

Acta Pharm. 2017 Sep 1;67(3):385-395. doi: 10.1515/acph-2017-0023.

PMID:
28858834
6.

Target fishing of glycopentalone using integrated inverse docking and reverse pharmacophore mapping approach.

Gurung AB, Ali MA, Bhattacharjee A, Al-Anazi KM, Farah MA, Al-Hemaid FM, Abou-Tarboush FM, Lee J, Kim SY, Al-Anazi FS.

Genet Mol Res. 2016 Aug 12;15(3). doi: 10.4238/gmr.15038544.

PMID:
27525951
7.

New palbociclib analogues modified at the terminal piperazine ring and their anticancer activities.

Wang P, Huang J, Wang K, Gu Y.

Eur J Med Chem. 2016 Oct 21;122:546-556. doi: 10.1016/j.ejmech.2016.07.020. Epub 2016 Jul 12.

PMID:
27448913
8.

Discovery of novel INK4C small-molecule inhibitors to promote human and murine hematopoietic stem cell ex vivo expansion.

Xie XQ, Yang P, Zhang Y, Zhang P, Wang L, Ding Y, Yang M, Tong Q, Cheng H, Ji Q, McGuire T, Yuan W, Cheng T, Gao Y.

Sci Rep. 2015 Dec 18;5:18115. doi: 10.1038/srep18115.

9.

Quantitative Relationships Between the Cytotoxicity of Flavonoids on the Human Breast Cancer Stem-Like Cells MCF7-SC and Their Structural Properties.

Jung H, Shin SY, Jung Y, Tran TA, Lee HO, Jung KY, Koh D, Cho SK, Lim Y.

Chem Biol Drug Des. 2015 Oct;86(4):496-508. doi: 10.1111/cbdd.12512. Epub 2015 Jan 31.

PMID:
25582302
10.

Rational design of the survivin/CDK4 complex by combining protein-protein docking and molecular dynamics simulations.

Selent J, Kaczor AA, Guixà-González R, Carrió P, Pastor M, Obiol-Pardo C.

J Mol Model. 2013 Apr;19(4):1507-14. doi: 10.1007/s00894-012-1705-8. Epub 2012 Dec 21.

PMID:
23263360
11.

Molecular dynamic behavior and binding affinity of flavonoid analogues to the cyclin dependent kinase 6/cyclin D complex.

Khuntawee W, Rungrotmongkol T, Hannongbua S.

J Chem Inf Model. 2012 Jan 23;52(1):76-83. doi: 10.1021/ci200304v. Epub 2011 Dec 29.

PMID:
22172011
12.

Galbanic acid decreases androgen receptor abundance and signaling and induces G1 arrest in prostate cancer cells.

Zhang Y, Kim KH, Zhang W, Guo Y, Kim SH, Lü J.

Int J Cancer. 2012 Jan 1;130(1):200-12. doi: 10.1002/ijc.25993. Epub 2011 May 9.

Supplemental Content

Loading ...
Support Center