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Items: 1 to 20 of 844


Corrigendum to "Sorafenib Dose Recommendation in Acute Myeloid Leukemia Based on Exposure-FLT3 Relationship".

[No authors listed]

Clin Transl Sci. 2018 Nov;11(6):624. doi: 10.1111/cts.12587. Epub 2018 Sep 21. No abstract available.


Chimeric Antigen Receptor T-Cells: Successful Translation of the First Cell and Gene Therapy From Bench to Bedside.

Rodriguez-Cartagena LG, Bowles BS, Kurani SS, Windebank AJ, Kenderian SS, Greenberg-Worisek AJ.

Clin Transl Sci. 2018 Nov;11(6):537-539. doi: 10.1111/cts.12586. Epub 2018 Sep 22. No abstract available.


Evaluation of Pharmacokinetics and Pharmacodynamics of BI 425809, a Novel GlyT1 Inhibitor: Translational Studies.

Rosenbrock H, Desch M, Kleiner O, Dorner-Ciossek C, Schmid B, Keller S, Schlecker C, Moschetti V, Goetz S, Liesenfeld KH, Fillon G, Giovannini R, Ramael S, Wunderlich G, Wind S.

Clin Transl Sci. 2018 Nov;11(6):616-623. doi: 10.1111/cts.12578. Epub 2018 Aug 23.


Evaluation of the Cardiac Safety of Long-Acting Endectocide Moxidectin in a Randomized Concentration-QT Study.

Kinrade SA, Mason JW, Sanabria CR, Rayner CR, Bullock JM, Stanworth SH, Sullivan MT.

Clin Transl Sci. 2018 Nov;11(6):582-589. doi: 10.1111/cts.12583. Epub 2018 Sep 19.


Assessment of Dermal Absorption of Aluminum from a Representative Antiperspirant Formulation Using a 26 Al Microtracer Approach.

de Ligt R, van Duijn E, Grossouw D, Bosgra S, Burggraaf J, Windhorst A, Peeters PAM, van der Luijt GA, Alexander-White C, Vaes WHJ.

Clin Transl Sci. 2018 Nov;11(6):573-581. doi: 10.1111/cts.12579. Epub 2018 Jul 27.


No Pharmacokinetic Interactions Between Elbasvir or Grazoprevir and Methadone in Participants Receiving Maintenance Opioid Agonist Therapy.

Feng HP, Guo Z, Caro L, Marshall WL, Liu F, Panebianco D, Vaddady P, Reitmann C, Jumes P, Wolford D, Fraser I, Valesky R, Martinho M, Butterton JR, Iwamoto M, Webster L, Yeh WW.

Clin Transl Sci. 2018 Nov;11(6):553-561. doi: 10.1111/cts.12564. Epub 2018 Jul 24.


No Pharmacokinetic Interactions Between Elbasvir or Grazoprevir and Buprenorphine/Naloxone in Healthy Participants and Participants Receiving Stable Opioid Agonist Therapy.

Feng HP, Guo Z, Caro L, Marshall WL, Liu F, Panebianco D, Vaddady P, Barbour A, Reitmann C, Jumes P, Gilmartin J, Wolford D, Valesky R, Martinho M, Butterton JR, Iwamoto M, Fraser I, Webster L, Yeh WW.

Clin Transl Sci. 2018 Nov;11(6):562-572. doi: 10.1111/cts.12565. Epub 2018 Jul 24.


Clinical Studies for the Sake of Negative Data: The Proof Is in the Pudding.

Robertson S.

Clin Transl Sci. 2018 Nov;11(6):535-536. doi: 10.1111/cts.12568. Epub 2018 Jul 10. No abstract available.


Drug-Drug Interaction Study of Apixaban with Cyclosporine and Tacrolimus in Healthy Volunteers.

Bashir B, Stickle DF, Chervoneva I, Kraft WK.

Clin Transl Sci. 2018 Nov;11(6):590-596. doi: 10.1111/cts.12580. Epub 2018 Jul 27.


Premarket Approval Through the 510(k) Process: Lessons from the Translation Process of Magnetic Resonance Elastography.

Aponte Ortiz JA, Konik E, Eckert EC, Pepin KM, Greenberg-Worisek A.

Clin Transl Sci. 2018 Sep;11(5):447-449. doi: 10.1111/cts.12581. Epub 2018 Jul 27. No abstract available.


Assay Guidance Manual: Quantitative Biology and Pharmacology in Preclinical Drug Discovery.

Coussens NP, Sittampalam GS, Guha R, Brimacombe K, Grossman A, Chung TDY, Weidner JR, Riss T, Trask OJ, Auld D, Dahlin JL, Devanaryan V, Foley TL, McGee J, Kahl SD, Kales SC, Arkin M, Baell J, Bejcek B, Gal-Edd N, Glicksman M, Haas JV, Iversen PW, Hoeppner M, Lathrop S, Sayers E, Liu H, Trawick B, McVey J, Lemmon VP, Li Z, McManus O, Minor L, Napper A, Wildey MJ, Pacifici R, Chin WW, Xia M, Xu X, Lal-Nag M, Hall MD, Michael S, Inglese J, Simeonov A, Austin CP.

Clin Transl Sci. 2018 Sep;11(5):461-470. doi: 10.1111/cts.12570. Epub 2018 Jul 24.


Prediction of Safety Margin and Optimization of Dosing Protocol for a Novel Antibiotic using Quantitative Systems Pharmacology Modeling.

Woodhead JL, Paech F, Maurer M, Engelhardt M, Schmitt-Hoffmann AH, Spickermann J, Messner S, Wind M, Witschi AT, Krähenbühl S, Siler SQ, Watkins PB, Howell BA.

Clin Transl Sci. 2018 Sep;11(5):498-505. doi: 10.1111/cts.12560. Epub 2018 Jun 7.


Population Pharmacokinetic and Exposure-dizziness Modeling for a Metabotropic Glutamate Receptor Subtype 5 Negative Allosteric Modulator in Major Depressive Disorder Patients.

Cosson V, Schaedeli-Stark F, Arab-Alameddine M, Chavanne C, Guerini E, Derks M, Mallalieu NL.

Clin Transl Sci. 2018 Sep;11(5):523-531. doi: 10.1111/cts.12566. Epub 2018 Jun 27.


Tutorial on Monoclonal Antibody Pharmacokinetics and Its Considerations in Early Development.

Ovacik M, Lin K.

Clin Transl Sci. 2018 Nov;11(6):540-552. doi: 10.1111/cts.12567. Epub 2018 Aug 7.


Effect of Dose and 5α-Reductase Inhibition on the Circulating Testosterone Metabolite Profile of Men Administered Oral Testosterone.

Basit A, Amory JK, Prasad B.

Clin Transl Sci. 2018 Sep;11(5):513-522. doi: 10.1111/cts.12569. Epub 2018 Jun 19.


Anisomycin Activates Utrophin Upregulation Through a p38 Signaling Pathway.

Hadwen J, Farooq F, Witherspoon L, Schock S, Mongeon K, MacKenzie A.

Clin Transl Sci. 2018 Sep;11(5):506-512. doi: 10.1111/cts.12562. Epub 2018 Jun 7.


Health Research Participation, Opportunity, and Willingness Among Minority and Rural Communities of Arkansas.

McElfish PA, Long CR, Selig JP, Rowland B, Purvis RS, James L, Holland A, Felix HC, Narcisse MR.

Clin Transl Sci. 2018 Sep;11(5):487-497. doi: 10.1111/cts.12561. Epub 2018 May 17.


Clinical Drug-Drug Interaction Potential of BFE1224, Prodrug of Antifungal Ravuconazole, Using Two Types of Cocktails in Healthy Subjects.

Ishii Y, Ito Y, Matsuki S, Sanpei K, Ogawa O, Takeda K, Schuck EL, Uemura N.

Clin Transl Sci. 2018 Sep;11(5):477-486. doi: 10.1111/cts.12557. Epub 2018 May 16.


Innovation at the Intersection of Clinical Trials and Real-World Data Science to Advance Patient Care.

Swift B, Jain L, White C, Chandrasekaran V, Bhandari A, Hughes DA, Jadhav PR.

Clin Transl Sci. 2018 Sep;11(5):450-460. doi: 10.1111/cts.12559. Epub 2018 May 16. Review.

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