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Items: 1 to 20 of 55

1.

Influenza Pathogenesis: The Effect of Host Factors on Severity of Disease.

Gounder AP, Boon ACM.

J Immunol. 2019 Jan 15;202(2):341-350. doi: 10.4049/jimmunol.1801010. Review.

PMID:
30617115
2.

Viral MHCI inhibition evades tissue-resident memory T cell formation and responses.

Lauron EJ, Yang L, Harvey IB, Sojka DK, Williams GD, Paley MA, Bern MD, Park E, Victorino F, Boon ACM, Yokoyama WM.

J Exp Med. 2019 Jan 7;216(1):117-132. doi: 10.1084/jem.20181077. Epub 2018 Dec 17.

PMID:
30559127
3.

Inflammation and lung injury in an ovine model of fluid resuscitated endotoxemic shock.

Passmore MR, Byrne L, Obonyo NG, See Hoe LE, Boon AC, Diab SD, Dunster KR, Bisht K, Tung JP, Fauzi MH, Narula M, Pedersen SE, Esguerra-Lallen A, Simonova G, Sultana A, Anstey CM, Shekar K, Maitland K, Suen JY, Fraser JF.

Respir Res. 2018 Nov 22;19(1):231. doi: 10.1186/s12931-018-0935-4.

4.

Unintended Consequences: Fluid Resuscitation Worsens Shock in an Ovine Model of Endotoxemia.

Byrne L, Obonyo NG, Diab SD, Dunster KR, Passmore MR, Boon AC, Hoe LS, Pedersen S, Fauzi MH, Pimenta LP, Van Haren F, Anstey CM, Cullen L, Tung JP, Shekar K, Maitland K, Fraser JF.

Am J Respir Crit Care Med. 2018 Oct 15;198(8):1043-1054. doi: 10.1164/rccm.201801-0064OC.

PMID:
29882682
5.

Interferon induced protein 35 exacerbates H5N1 influenza disease through the expression of IL-12p40 homodimer.

Gounder AP, Yokoyama CC, Jarjour NN, Bricker TL, Edelson BT, Boon ACM.

PLoS Pathog. 2018 Apr 26;14(4):e1007001. doi: 10.1371/journal.ppat.1007001. eCollection 2018 Apr.

6.

Bilirubin acts as a multipotent guardian of cardiovascular integrity: more than just a radical idea.

Bulmer AC, Bakrania B, Du Toit EF, Boon AC, Clark PJ, Powell LW, Wagner KH, Headrick JP.

Am J Physiol Heart Circ Physiol. 2018 Sep 1;315(3):H429-H447. doi: 10.1152/ajpheart.00417.2017. Epub 2018 Mar 30.

PMID:
29600900
7.

Irg1 expression in myeloid cells prevents immunopathology during M. tuberculosis infection.

Nair S, Huynh JP, Lampropoulou V, Loginicheva E, Esaulova E, Gounder AP, Boon ACM, Schwarzkopf EA, Bradstreet TR, Edelson BT, Artyomov MN, Stallings CL, Diamond MS.

J Exp Med. 2018 Apr 2;215(4):1035-1045. doi: 10.1084/jem.20180118. Epub 2018 Mar 6.

8.

Nucleotide resolution mapping of influenza A virus nucleoprotein-RNA interactions reveals RNA features required for replication.

Williams GD, Townsend D, Wylie KM, Kim PJ, Amarasinghe GK, Kutluay SB, Boon ACM.

Nat Commun. 2018 Jan 31;9(1):465. doi: 10.1038/s41467-018-02886-w.

9.

The microbial metabolite desaminotyrosine protects from influenza through type I interferon.

Steed AL, Christophi GP, Kaiko GE, Sun L, Goodwin VM, Jain U, Esaulova E, Artyomov MN, Morales DJ, Holtzman MJ, Boon ACM, Lenschow DJ, Stappenbeck TS.

Science. 2017 Aug 4;357(6350):498-502. doi: 10.1126/science.aam5336.

10.

An Ovine Model of Hyperdynamic Endotoxemia and Vital Organ Metabolism.

Byrne L, Obonyo NG, Diab S, Dunster K, Passmore M, Boon AC, Hoe LS, Hay K, Van Haren F, Tung JP, Cullen L, Shekar K, Maitland K, Fraser JF.

Shock. 2018 Jan;49(1):99-107. doi: 10.1097/SHK.0000000000000904.

11.

Residues in the PB2 and PA genes contribute to the pathogenicity of avian H7N3 influenza A virus in DBA/2 mice.

DesRochers BL, Chen RE, Gounder AP, Pinto AK, Bricker T, Linton CN, Rogers CD, Williams GD, Webby RJ, Boon AC.

Virology. 2016 Jul;494:89-99. doi: 10.1016/j.virol.2016.04.013. Epub 2016 Apr 20.

12.

A North American H7N3 Influenza Virus Supports Reassortment with 2009 Pandemic H1N1 and Induces Disease in Mice without Prior Adaptation.

Williams GD, Pinto AK, Doll B, Boon ACM.

J Virol. 2016 Apr 14;90(9):4796-4806. doi: 10.1128/JVI.02761-15. Print 2016 May.

13.

Homeostatic Control of Innate Lung Inflammation by Vici Syndrome Gene Epg5 and Additional Autophagy Genes Promotes Influenza Pathogenesis.

Lu Q, Yokoyama CC, Williams JW, Baldridge MT, Jin X, DesRochers B, Bricker T, Wilen CB, Bagaitkar J, Loginicheva E, Sergushichev A, Kreamalmeyer D, Keller BC, Zhao Y, Kambal A, Green DR, Martinez J, Dinauer MC, Holtzman MJ, Crouch EC, Beatty W, Boon AC, Zhang H, Randolph GJ, Artyomov MN, Virgin HW.

Cell Host Microbe. 2016 Jan 13;19(1):102-13. doi: 10.1016/j.chom.2015.12.011.

14.

Endogenously elevated bilirubin modulates kidney function and protects from circulating oxidative stress in a rat model of adenine-induced kidney failure.

Boon AC, Lam AK, Gopalan V, Benzie IF, Briskey D, Coombes JS, Fassett RG, Bulmer AC.

Sci Rep. 2015 Oct 26;5:15482. doi: 10.1038/srep15482.

15.

Human and Murine IFIT1 Proteins Do Not Restrict Infection of Negative-Sense RNA Viruses of the Orthomyxoviridae, Bunyaviridae, and Filoviridae Families.

Pinto AK, Williams GD, Szretter KJ, White JP, Proença-Módena JL, Liu G, Olejnik J, Brien JD, Ebihara H, Mühlberger E, Amarasinghe G, Diamond MS, Boon AC.

J Virol. 2015 Sep;89(18):9465-76. doi: 10.1128/JVI.00996-15. Epub 2015 Jul 8.

16.

Bilirubin scavenges chloramines and inhibits myeloperoxidase-induced protein/lipid oxidation in physiologically relevant hyperbilirubinemic serum.

Boon AC, Hawkins CL, Coombes JS, Wagner KH, Bulmer AC.

Free Radic Biol Med. 2015 Sep;86:259-68. doi: 10.1016/j.freeradbiomed.2015.05.031. Epub 2015 Jun 6.

PMID:
26057938
17.

An anti-H5N1 influenza virus FcDART antibody is a highly efficacious therapeutic agent and prophylactic against H5N1 influenza virus infection.

Zanin M, Keck ZY, Rainey GJ, Lam CY, Boon AC, Rubrum A, Darnell D, Wong SS, Griffin Y, Xia J, Webster RG, Webby R, Johnson S, Foung S.

J Virol. 2015 Apr;89(8):4549-61. doi: 10.1128/JVI.00078-15. Epub 2015 Feb 11.

18.

A novel genetic locus linked to pro-inflammatory cytokines after virulent H5N1 virus infection in mice.

Boon AC, Williams RW, Sinasac DS, Webby RJ.

BMC Genomics. 2014 Nov 24;15:1017. doi: 10.1186/1471-2164-15-1017.

19.

Circulating bilirubin and defense against kidney disease and cardiovascular mortality: mechanisms contributing to protection in clinical investigations.

Boon AC, Bulmer AC, Coombes JS, Fassett RG.

Am J Physiol Renal Physiol. 2014 Jul 15;307(2):F123-36. doi: 10.1152/ajprenal.00039.2014. Epub 2014 Apr 23. Review.

20.

Binding of DC-SIGN to the hemagglutinin of influenza A viruses supports virus replication in DC-SIGN expressing cells.

Hillaire ML, Nieuwkoop NJ, Boon AC, de Mutsert G, Vogelzang-van Trierum SE, Fouchier RA, Osterhaus AD, Rimmelzwaan GF.

PLoS One. 2013;8(2):e56164. doi: 10.1371/journal.pone.0056164. Epub 2013 Feb 12.

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