Role of molecular chaperones in biogenesis of the protein kinome.

Ydj1 protects nascent protein kinases from degradation and controls the rate of their maturation.

A positive feedback loop between protein kinase CKII and Cdc37 promotes the activity of multiple protein kinases.

Review Cdc37 regulation of the kinome: when to hold 'em and when to fold 'em.

Review Protein kinase CK2 in health and disease: CK2: the kinase controlling the Hsp90 chaperone machinery.

Atomistic simulations and network-based modeling of the Hsp90-Cdc37 chaperone binding with Cdk4 client protein: A mechanism of chaperoning kinase clients by exploiting weak spots of intrinsically dynamic kinase domains.

DYRK1B mutations associated with metabolic syndrome impair the chaperone-dependent maturation of the kinase domain.

An Hsp90 co-chaperone protein in yeast is functionally replaced by site-specific posttranslational modification in humans.