Significant up-regulation of a novel gene, CLCP1, in a highly metastatic lung cancer subline as well as in lung cancers in vivo.

Hypoxia and hypoxia-inducible factor 1 repress SEMA4B expression to promote non-small cell lung cancer invasion.

SEMA4B inhibits growth of non-small cell lung cancer in vitro and in vivo.

SEMA4b inhibits MMP9 to prevent metastasis of non-small cell lung cancer.

Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability.

A reverse signaling pathway downstream of Sema4A controls cell migration via Scrib.

Review Semaphorins and their Signaling Mechanisms.

Review Transmembrane semaphorins: Multimodal signaling cues in development and cancer.