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Nicastrin is required for assembly of presenilin/gamma-secretase complexes to mediate Notch signaling and for processing and trafficking of beta-amyloid precursor protein in mammals.[J Neurosci. 2003]
Nicastrin is required for assembly of presenilin/gamma-secretase complexes to mediate Notch signaling and for processing and trafficking of beta-amyloid precursor protein in mammals.
Li T, Ma G, Cai H, Price DL, Wong PC. J Neurosci. 2003 Apr 15; 23(8):3272-7.
Review Roles of glycogen synthase kinase 3 in Alzheimer's disease.[Curr Alzheimer Res. 2012]
Review Roles of glycogen synthase kinase 3 in Alzheimer's disease.
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Proteolytic processing of the Alzheimer's disease amyloid precursor protein in brain and platelets.[J Neurosci Res. 2003]
Proteolytic processing of the Alzheimer's disease amyloid precursor protein in brain and platelets.
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Diet-induced insulin resistance promotes amyloidosis in a transgenic mouse model of Alzheimer's disease.[FASEB J. 2004]
Diet-induced insulin resistance promotes amyloidosis in a transgenic mouse model of Alzheimer's disease.
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Review Genes and mechanisms involved in beta-amyloid generation and Alzheimer's disease.[Eur Arch Psychiatry Clin Neuro...]
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Steiner H, Capell A, Leimer U, Haass C. Eur Arch Psychiatry Clin Neurosci. 1999; 249(6):266-70.

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A Novel Therapeutic Approach to Treat Alzheimer's Disease by Neurotrophic Support During the Period of Synaptic Compensation.[J Alzheimers Dis. 2018]
A Novel Therapeutic Approach to Treat Alzheimer's Disease by Neurotrophic Support During the Period of Synaptic Compensation.
Baazaoui N, Iqbal K. J Alzheimers Dis. 2018; 62(3):1211-1218.
Dual GSK-3β/AChE Inhibitors as a New Strategy for Multitargeting Anti-Alzheimer's Disease Drug Discovery.[ACS Med Chem Lett. 2018]
Dual GSK-3β/AChE Inhibitors as a New Strategy for Multitargeting Anti-Alzheimer's Disease Drug Discovery.
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Review Mechanisms linking brain insulin resistance to Alzheimer's disease.[Dement Neuropsychol. 2015]
Review Mechanisms linking brain insulin resistance to Alzheimer's disease.
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