The effect of various nucleotides on the helical nature of a ribosomal protein(s) from Escherichia coli

Proc Natl Acad Sci U S A. 1972 Aug;69(8):2120-1. doi: 10.1073/pnas.69.8.2120.

Abstract

In the presence of GTP or GDP, there is a decrease in the circular dichroic absorption of ribosomal proteins L(7) and L(12) at 221-222 nm, suggesting that these nucleotides influence the helical content of these proteins.

MeSH terms

  • Adenosine Triphosphate / pharmacology
  • Bacterial Proteins / isolation & purification*
  • Circular Dichroism
  • Escherichia coli / analysis
  • Guanine Nucleotides / pharmacology
  • Guanosine Triphosphate / pharmacology
  • Methods
  • Nucleotides / pharmacology*
  • Protein Conformation / drug effects*
  • Ribosomes / drug effects*
  • Spectrum Analysis

Substances

  • Bacterial Proteins
  • Guanine Nucleotides
  • Nucleotides
  • Guanosine Triphosphate
  • Adenosine Triphosphate