Cardiac Cell Therapy Fails to Rejuvenate the Chronically Scarred Rodent Heart

Circulation. 2021 Jul 27;144(4):328-331. doi: 10.1161/CIRCULATIONAHA.120.053080. Epub 2021 Jul 26.

Authors

Ronald J Vagnozzi^{1

2}, Rajesh K Kasam¹, Michelle A Sargent¹, Jeffery D Molkentin^{1

3}

Affiliations

¹ Department of Pediatrics, University of Cincinnati (R.J.V., R.K.K., M.A.S., J.D.M.), Cincinnati Children's Hospital Medical Center, OH.
² Division of Cardiology, Department of Medicine, Consortium for Fibrosis Research and Translation, University of Colorado Anschutz Medical Campus, Aurora (R.J.V.).
³ Howard Hughes Medical Institute (J.D.M.), Cincinnati Children's Hospital Medical Center, OH.

No abstract available

Keywords: cell- and tissue-based therapy; models, animal; myocardial infarction; stem cells.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Bone Marrow Cells
Bone Marrow Transplantation
Cardiomyopathy, Restrictive / diagnosis
Cardiomyopathy, Restrictive / etiology*
Cardiomyopathy, Restrictive / therapy*
Cell- and Tissue-Based Therapy / methods*
Chronic Disease
Disease Models, Animal
Female
Fibrosis
Ischemia / complications
Male
Mice
Rodentia
Stem Cell Transplantation*
Treatment Failure
Treatment Outcome

Grants and funding