Changes in allele frequencies of CSF3R and SETBP1 mutations and evidence of clonal evolution in a chronic neutrophilic leukemia patient treated with ruxolitinib

MeSH terms

• Antineoplastic Agents / therapeutic use
• Bone Marrow / pathology
• Carrier Proteins / genetics*
• Clonal Evolution / drug effects
• Clonal Evolution / genetics*
• Disease Progression
• Gene Frequency*
• Humans
• Leukemia, Neutrophilic, Chronic / drug therapy*
• Leukemia, Neutrophilic, Chronic / genetics*
• Leukemia, Neutrophilic, Chronic / pathology
• Leukocyte Count
• Mutation*
• Nitriles
• Nuclear Proteins / genetics*
• Protein Kinase Inhibitors / therapeutic use
• Pyrazoles / pharmacology
• Pyrazoles / therapeutic use*
• Pyrimidines
• Receptors, Colony-Stimulating Factor / genetics*
• Treatment Outcome