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Items: 1 to 20 of 153

1.

Targeting Energy Metabolism by a Platinum(IV) Prodrug as an Alternative Pathway for Cancer Suppression.

Jin S, Guo Y, Song D, Zhu Z, Zhang Z, Sun Y, Yang T, Guo Z, Wang X.

Inorg Chem. 2019 May 6;58(9):6507-6516. doi: 10.1021/acs.inorgchem.9b00708. Epub 2019 Apr 23.

PMID:
31013065
2.

Mitochondrion-targeted platinum complexes suppressing lung cancer through multiple pathways involving energy metabolism.

Zhu Z, Wang Z, Zhang C, Wang Y, Zhang H, Gan Z, Guo Z, Wang X.

Chem Sci. 2019 Jan 22;10(10):3089-3095. doi: 10.1039/c8sc04871a. eCollection 2019 Mar 14.

3.

Inhibiting Aβ toxicity in Alzheimer's disease by a pyridine amine derivative.

Zhu Z, Yang T, Zhang L, Liu L, Yin E, Zhang C, Guo Z, Xu C, Wang X.

Eur J Med Chem. 2019 Apr 15;168:330-339. doi: 10.1016/j.ejmech.2019.02.052. Epub 2019 Feb 20.

PMID:
30826509
4.

A platinum(iv) prodrug to defeat breast cancer through disrupting vasculature and inhibiting metastasis.

Guo Y, Zhang S, Yuan H, Song D, Jin S, Guo Z, Wang X.

Dalton Trans. 2019 Mar 12;48(11):3571-3575. doi: 10.1039/c9dt00335e.

PMID:
30793153
5.

Restraining Cancer Cells by Dual Metabolic Inhibition with a Mitochondrion-Targeted Platinum(II) Complex.

Wang K, Zhu C, He Y, Zhang Z, Zhou W, Muhammad N, Guo Y, Wang X, Guo Z.

Angew Chem Int Ed Engl. 2019 Mar 26;58(14):4638-4643. doi: 10.1002/anie.201900387. Epub 2019 Feb 27.

PMID:
30693616
6.

Med19 is targeted by miR-101-3p/miR-422a and promotes breast cancer progression by regulating the EGFR/MEK/ERK signaling pathway.

Zhang X, Gao D, Fang K, Guo Z, Li L.

Cancer Lett. 2019 Mar 1;444:105-115. doi: 10.1016/j.canlet.2018.12.008. Epub 2018 Dec 21.

PMID:
30583076
7.

hsa_circRNA_0006528 as a competing endogenous RNA promotes human breast cancer progression by sponging miR-7-5p and activating the MAPK/ERK signaling pathway.

Gao D, Qi X, Zhang X, Fang K, Guo Z, Li L.

Mol Carcinog. 2019 Apr;58(4):554-564. doi: 10.1002/mc.22950. Epub 2018 Dec 21.

PMID:
30520151
8.

Anticancer copper complex with nucleus, mitochondrion and cyclooxygenase-2 as multiple targets.

Shi X, Fang H, Guo Y, Yuan H, Guo Z, Wang X.

J Inorg Biochem. 2019 Jan;190:38-44. doi: 10.1016/j.jinorgbio.2018.10.003. Epub 2018 Oct 15.

PMID:
30352314
9.

Modulating Conformation of Aβ-Peptide: An Effective Way to Prevent Protein-Misfolding Disease.

Ma X, Hua J, Wang K, Zhang H, Zhang C, He Y, Guo Z, Wang X.

Inorg Chem. 2018 Nov 5;57(21):13533-13543. doi: 10.1021/acs.inorgchem.8b02115. Epub 2018 Oct 22.

PMID:
30345755
10.

Stimuli-Responsive Therapeutic Metallodrugs.

Wang X, Wang X, Jin S, Muhammad N, Guo Z.

Chem Rev. 2019 Jan 23;119(2):1138-1192. doi: 10.1021/acs.chemrev.8b00209. Epub 2018 Oct 9.

PMID:
30299085
11.

Towards rational design of RAD51-targeting prodrugs: platinumIV-artesunate conjugates with enhanced cytotoxicity against BRCA-proficient ovarian and breast cancer cells.

Zhang S, Yuan H, Guo Y, Wang K, Wang X, Guo Z.

Chem Commun (Camb). 2018 Oct 16;54(83):11717-11720. doi: 10.1039/c8cc06576d.

PMID:
30229259
12.

Med19 is involved in chemoresistance by mediating autophagy through HMGB1 in breast cancer.

Liu B, Qi X, Zhang X, Gao D, Fang K, Guo Z, Li L.

J Cell Biochem. 2019 Jan;120(1):507-518. doi: 10.1002/jcb.27406. Epub 2018 Aug 30.

PMID:
30161287
13.

Impact of Mitochondrion-Targeting Group on the Reactivity and Cytostatic Pathway of Platinum(IV) Complexes.

Jin S, Hao Y, Zhu Z, Muhammad N, Zhang Z, Wang K, Guo Y, Guo Z, Wang X.

Inorg Chem. 2018 Sep 4;57(17):11135-11145. doi: 10.1021/acs.inorgchem.8b01707. Epub 2018 Aug 17.

PMID:
30117731
14.

Coumarin/BODIPY Hybridisation for Ratiometric Sensing of Intracellular Polarity Oscillation.

Bai Y, Shi X, Chen Y, Zhu C, Jiao Y, Han Z, He W, Guo Z.

Chemistry. 2018 May 23;24(29):7513-7524. doi: 10.1002/chem.201800915. Epub 2018 Apr 30.

PMID:
29575108
15.

Hypotoxic copper complexes with potent anti-metastatic and anti-angiogenic activities against cancer cells.

Shi X, Chen Z, Wang Y, Guo Z, Wang X.

Dalton Trans. 2018 Apr 3;47(14):5049-5054. doi: 10.1039/C8DT00794B.

PMID:
29561011
16.

Editorial overview: Bioinorganic chemistry: Bio-medicinal functions of metal complexes.

Guo Z, Zhao J.

Curr Opin Chem Biol. 2018 Apr;43:A4-A5. doi: 10.1016/j.cbpa.2018.02.013. No abstract available.

PMID:
29526306
17.

A Potential Bone-Targeting Hypotoxic Platinum(II) Complex with an Unusual Cytostatic Mechanism toward Osteosarcoma Cells.

Zhang Z, Zhu Z, Luo C, Zhu C, Zhang C, Guo Z, Wang X.

Inorg Chem. 2018 Mar 19;57(6):3315-3322. doi: 10.1021/acs.inorgchem.7b03261. Epub 2018 Mar 7.

PMID:
29513007
18.

Mediation analysis for count and zero-inflated count data without sequential ignorability and its application in dental studies.

Guo Z, Small DS, Gansky SA, Cheng J.

J R Stat Soc Ser C Appl Stat. 2018 Feb;67(2):371-394. doi: 10.1111/rssc.12233. Epub 2017 Jul 15.

19.

Biotin-tagged platinum(iv) complexes as targeted cytostatic agents against breast cancer cells.

Muhammad N, Sadia N, Zhu C, Luo C, Guo Z, Wang X.

Chem Commun (Camb). 2017 Sep 5;53(72):9971-9974. doi: 10.1039/c7cc05311h.

PMID:
28831477
20.

Screening circular RNA related to chemotherapeutic resistance in breast cancer.

Gao D, Zhang X, Liu B, Meng D, Fang K, Guo Z, Li L.

Epigenomics. 2017 Sep;9(9):1175-1188. doi: 10.2217/epi-2017-0055. Epub 2017 Aug 14.

PMID:
28803498

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