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Items: 1 to 20 of 44

1.

Targeting ATG4 in Cancer Therapy.

Fu Y, Huang Z, Hong L, Lu JH, Feng D, Yin XM, Li M.

Cancers (Basel). 2019 May 10;11(5). pii: E649. doi: 10.3390/cancers11050649. Review.

2.

Triptolide induces oxidative damage in NRK-52E cells through facilitating Nrf2 degradation by ubiquitination via the GSK-3β/Fyn pathway.

Pan J, Shen F, Tian K, Wang M, Xi Y, Li J, Huang Z.

Toxicol In Vitro. 2019 Aug;58:187-194. doi: 10.1016/j.tiv.2019.03.032. Epub 2019 Mar 26.

PMID:
30926361
3.

Elevated lipoprotein (a) levels are associated with the acute myocardial infarction in patients with normal low-density lipoprotein cholesterol levels.

Cai G, Huang Z, Zhang B, Yu L, Li L.

Biosci Rep. 2019 Apr 5;39(4). pii: BSR20182096. doi: 10.1042/BSR20182096. Print 2019 Apr 30.

4.

A preliminary study showing no association between methylation levels of C3 gene promoter and the risk of CAD.

Cai G, Huang Z, Yu L, Li L.

Lipids Health Dis. 2019 Jan 5;18(1):5. doi: 10.1186/s12944-018-0949-4.

5.
6.

Triptolide impairs thioredoxin system by suppressing Notch1-mediated PTEN/Akt/Txnip signaling in hepatocytes.

Shen F, Xiong Z, Kong J, Wang L, Cheng Y, Jin J, Huang Z.

Toxicol Lett. 2019 Jan;300:105-115. doi: 10.1016/j.toxlet.2018.10.024. Epub 2018 Oct 28.

PMID:
30394310
7.

Assessment of the Pig-a, micronucleus, and comet assay endpoints in rats treated by acute or repeated dosing protocols with procarbazine hydrochloride and ethyl carbamate.

Chen G, Wen H, Mao Z, Song J, Jiang H, Wang W, Yang Y, Miao Y, Wang C, Huang Z, Wang X.

Environ Mol Mutagen. 2019 Jan;60(1):56-71. doi: 10.1002/em.22227. Epub 2018 Sep 21.

PMID:
30240497
8.

Serum PCSK9 levels, but not PCSK9 polymorphisms, are associated with CAD risk and lipid profiles in southern Chinese Han population.

Cai G, Yu L, Huang Z, Li L, Fu X.

Lipids Health Dis. 2018 Sep 11;17(1):213. doi: 10.1186/s12944-018-0859-5.

9.

Discovery of a small molecule targeting autophagy via ATG4B inhibition and cell death of colorectal cancer cells in vitro and in vivo.

Fu Y, Hong L, Xu J, Zhong G, Gu Q, Gu Q, Guan Y, Zheng X, Dai Q, Luo X, Liu C, Huang Z, Yin XM, Liu P, Li M.

Autophagy. 2019 Feb;15(2):295-311. doi: 10.1080/15548627.2018.1517073. Epub 2018 Sep 20.

PMID:
30176161
10.

Triptolide induces p53-dependent cardiotoxicity through mitochondrial membrane permeabilization in cardiomyocytes.

Xi Y, Wang W, Wang L, Pan J, Cheng Y, Shen F, Huang Z.

Toxicol Appl Pharmacol. 2018 Sep 15;355:269-285. doi: 10.1016/j.taap.2018.07.011. Epub 2018 Jul 20.

PMID:
30009776
11.

Triptolide-induced mitochondrial damage dysregulates fatty acid metabolism in mouse sertoli cells.

Cheng Y, Chen G, Wang L, Kong J, Pan J, Xi Y, Shen F, Huang Z.

Toxicol Lett. 2018 Aug;292:136-150. doi: 10.1016/j.toxlet.2018.04.035. Epub 2018 Apr 30.

PMID:
29723566
12.

Triptolide induces mitochondria-mediated apoptosis of Burkitt's lymphoma cell via deacetylation of GSK-3β by increased SIRT3 expression.

Kong J, Wang L, Ren L, Yan Y, Cheng Y, Huang Z, Shen F.

Toxicol Appl Pharmacol. 2018 Mar 1;342:1-13. doi: 10.1016/j.taap.2018.01.011. Epub 2018 Feb 4.

PMID:
29407771
13.

Epigenetic regulation of active Chinese herbal components for cancer prevention and treatment: A follow-up review.

Huang Z, Huang Q, Ji L, Wang Y, Qi X, Liu L, Liu Z, Lu L.

Pharmacol Res. 2016 Dec;114:1-12. doi: 10.1016/j.phrs.2016.09.023. Epub 2016 Sep 30. Review.

PMID:
27697644
14.

Inhibition of glycogen synthase kinase 3beta ameliorates triptolide-induced acute cardiac injury by desensitizing mitochondrial permeability transition.

Wang W, Yang Y, Xiong Z, Kong J, Fu X, Shen F, Huang Z.

Toxicol Appl Pharmacol. 2016 Dec 15;313:195-203. doi: 10.1016/j.taap.2016.10.007. Epub 2016 Oct 15.

PMID:
27751939
15.

Immunotoxicological Evaluation of Genetically Modified Rice Expressing Cry1Ab/Ac Protein (TT51-1) by a 6-Month Feeding Study on Cynomolgus Monkeys.

Tan X, Zhou X, Tang Y, Lv J, Zhang L, Sun L, Yang Y, Miao Y, Jiang H, Chen G, Huang Z, Wang X.

PLoS One. 2016 Sep 29;11(9):e0163879. doi: 10.1371/journal.pone.0163879. eCollection 2016.

16.

Resveratrol protects against triptolide-induced cardiotoxicity through SIRT3 signaling pathway in vivo and in vitro.

Yang Y, Wang W, Xiong Z, Kong J, Wang L, Qiu Y, Shen F, Huang Z.

Pharmazie. 2016 Sep 1;71(9):514-523. doi: 10.1691/ph.2016.6597.

PMID:
29441847
17.

Tanshinone IIA protects against acetaminophen-induced hepatotoxicity via activating the Nrf2 pathway.

Wang W, Guan C, Sun X, Zhao Z, Li J, Fu X, Qiu Y, Huang M, Jin J, Huang Z.

Phytomedicine. 2016 Jun 1;23(6):589-96. doi: 10.1016/j.phymed.2016.02.022. Epub 2016 Mar 22.

PMID:
27161400
18.

Activation of SIRT3 attenuates triptolide-induced toxicity through closing mitochondrial permeability transition pore in cardiomyocytes.

Yang Y, Wang W, Xiong Z, Kong J, Qiu Y, Shen F, Huang Z.

Toxicol In Vitro. 2016 Aug;34:128-137. doi: 10.1016/j.tiv.2016.03.020. Epub 2016 Apr 8.

PMID:
27064125
19.

Optimized Animal Model of Cyclophosphamide-induced Bone Marrow Suppression.

Feng L, Huang Q, Huang Z, Li H, Qi X, Wang Y, Liu Z, Liu X, Lu L.

Basic Clin Pharmacol Toxicol. 2016 Nov;119(5):428-435. doi: 10.1111/bcpt.12600. Epub 2016 May 27.

20.

Activation of the farnesoid X receptor attenuates triptolide-induced liver toxicity.

Jin J, Sun X, Zhao Z, Wang W, Qiu Y, Fu X, Huang M, Huang Z.

Phytomedicine. 2015 Sep 15;22(10):894-901. doi: 10.1016/j.phymed.2015.06.007. Epub 2015 Jul 3.

PMID:
26321738

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