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Items: 1 to 20 of 54


A novel artificial intelligence system for the assessment of bowel preparation (with video).

Zhou J, Wu L, Wan X, Shen L, Liu J, Zhang J, Jiang X, Wang Z, Yu S, Kang J, Li M, Hu S, Hu X, Gong D, Chen D, Yao L, Zhu Y, Yu H.

Gastrointest Endosc. 2019 Nov 26. pii: S0016-5107(19)32476-9. doi: 10.1016/j.gie.2019.11.026. [Epub ahead of print]


Novel deazaflavin tyrosyl-DNA phosphodiesterase 2 (TDP2) inhibitors.

Kiselev E, Ravji A, Kankanala J, Xie J, Wang Z, Pommier Y.

DNA Repair (Amst). 2020 Jan;85:102747. doi: 10.1016/j.dnarep.2019.102747. Epub 2019 Nov 6.


Aerial Cooperative Jamming for Cellular-Enabled UAV Secure Communication Network: Joint Trajectory and Power Control Design.

Sun H, Duo B, Wang Z, Lin X, Gao C.

Sensors (Basel). 2019 Oct 14;19(20). pii: E4440. doi: 10.3390/s19204440.


Determinants of Active-Site Inhibitor Interaction with HIV-1 RNase H.

Xi Z, Wang Z, Sarafianos SG, Myshakina NS, Ishima R.

ACS Infect Dis. 2019 Nov 8;5(11):1963-1974. doi: 10.1021/acsinfecdis.9b00300. Epub 2019 Oct 2.


Price-Based Resource Allocation in Wireless Power Transfer-Enabled Massive MIMO Networks.

Wang Z, Huang K, Yang X, Wan X, Fan Z, Xu Y.

Sensors (Basel). 2019 Jul 26;19(15). pii: E3298. doi: 10.3390/s19153298.


Challenges and Opportunities in Hepatitis B Research.

Wang Z.

ACS Infect Dis. 2019 May 10;5(5):652-654. doi: 10.1021/acsinfecdis.9b00136. No abstract available.


Novel Deazaflavin Analogues Potently Inhibited Tyrosyl DNA Phosphodiesterase 2 (TDP2) and Strongly Sensitized Cancer Cells toward Treatment with Topoisomerase II (TOP2) Poison Etoposide.

Kankanala J, Ribeiro CJA, Kiselev E, Ravji A, Williams J, Xie J, Aihara H, Pommier Y, Wang Z.

J Med Chem. 2019 May 9;62(9):4669-4682. doi: 10.1021/acs.jmedchem.9b00274. Epub 2019 Apr 30.


A deep neural network improves endoscopic detection of early gastric cancer without blind spots.

Wu L, Zhou W, Wan X, Zhang J, Shen L, Hu S, Ding Q, Mu G, Yin A, Huang X, Liu J, Jiang X, Wang Z, Deng Y, Liu M, Lin R, Ling T, Li P, Wu Q, Jin P, Chen J, Yu H.

Endoscopy. 2019 Jun;51(6):522-531. doi: 10.1055/a-0855-3532. Epub 2019 Mar 12.


Pharmacophore-based design of novel 3-hydroxypyrimidine-2,4-dione subtypes as inhibitors of HIV reverse transcriptase-associated RNase H: Tolerance of a nonflexible linker.

Tang J, Do HT, Huber AD, Casey MC, Kirby KA, Wilson DJ, Kankanala J, Parniak MA, Sarafianos SG, Wang Z.

Eur J Med Chem. 2019 Mar 15;166:390-399. doi: 10.1016/j.ejmech.2019.01.081. Epub 2019 Feb 2.


5-Aminothiophene-2,4-dicarboxamide analogues as hepatitis B virus capsid assembly effectors.

Tang J, Huber AD, Pineda DL, Boschert KN, Wolf JJ, Kankanala J, Xie J, Sarafianos SG, Wang Z.

Eur J Med Chem. 2019 Feb 15;164:179-192. doi: 10.1016/j.ejmech.2018.12.047. Epub 2018 Dec 21.


Novel Hepatitis B Virus Capsid-Targeting Antiviral That Aggregates Core Particles and Inhibits Nuclear Entry of Viral Cores.

Huber AD, Pineda DL, Liu D, Boschert KN, Gres AT, Wolf JJ, Coonrod EM, Tang J, Laughlin TG, Yang Q, Puray-Chavez MN, Ji J, Singh K, Kirby KA, Wang Z, Sarafianos SG.

ACS Infect Dis. 2019 May 10;5(5):750-758. doi: 10.1021/acsinfecdis.8b00235. Epub 2019 Jan 14.


Triazolopyrimidine and triazolopyridine scaffolds as TDP2 inhibitors.

Ribeiro CJA, Kankanala J, Xie J, Williams J, Aihara H, Wang Z.

Bioorg Med Chem Lett. 2019 Jan 15;29(2):257-261. doi: 10.1016/j.bmcl.2018.11.044. Epub 2018 Nov 22.


6-Biphenylmethyl-3-hydroxypyrimidine-2,4-diones potently and selectively inhibited HIV reverse transcriptase-associated RNase H.

Wang L, Tang J, Huber AD, Casey MC, Kirby KA, Wilson DJ, Kankanala J, Parniak MA, Sarafianos SG, Wang Z.

Eur J Med Chem. 2018 Aug 5;156:680-691. doi: 10.1016/j.ejmech.2018.07.035. Epub 2018 Jul 17.


6-Arylthio-3-hydroxypyrimidine-2,4-diones potently inhibited HIV reverse transcriptase-associated RNase H with antiviral activity.

Wang L, Tang J, Huber AD, Casey MC, Kirby KA, Wilson DJ, Kankanala J, Xie J, Parniak MA, Sarafianos SG, Wang Z.

Eur J Med Chem. 2018 Aug 5;156:652-665. doi: 10.1016/j.ejmech.2018.07.039. Epub 2018 Jul 17.


Hydroxypyridonecarboxylic Acids as Inhibitors of Human Cytomegalovirus pUL89 Endonuclease.

Kankanala J, Wang Y, Geraghty RJ, Wang Z.

ChemMedChem. 2018 Aug 20;13(16):1658-1663. doi: 10.1002/cmdc.201800283. Epub 2018 Jul 20.


The Heteroaryldihydropyrimidine Bay 38-7690 Induces Hepatitis B Virus Core Protein Aggregates Associated with Promyelocytic Leukemia Nuclear Bodies in Infected Cells.

Huber AD, Wolf JJ, Liu D, Gres AT, Tang J, Boschert KN, Puray-Chavez MN, Pineda DL, Laughlin TG, Coonrod EM, Yang Q, Ji J, Kirby KA, Wang Z, Sarafianos SG.

mSphere. 2018 Apr 18;3(2). pii: e00131-18. doi: 10.1128/mSphereDirect.00131-18. Print 2018 Apr 25.


The substrate-binding cap of the UDP-diacylglucosamine pyrophosphatase LpxH is highly flexible, enabling facile substrate binding and product release.

Bohl TE, Ieong P, Lee JK, Lee T, Kankanala J, Shi K, Demir Ö, Kurahashi K, Amaro RE, Wang Z, Aihara H.

J Biol Chem. 2018 May 25;293(21):7969-7981. doi: 10.1074/jbc.RA118.002503. Epub 2018 Apr 6.


New fluorescence-based high-throughput screening assay for small molecule inhibitors of tyrosyl-DNA phosphodiesterase 2 (TDP2).

Ribeiro CJA, Kankanala J, Shi K, Kurahashi K, Kiselev E, Ravji A, Pommier Y, Aihara H, Wang Z.

Eur J Pharm Sci. 2018 Jun 15;118:67-79. doi: 10.1016/j.ejps.2018.03.021. Epub 2018 Mar 21.


Metal-chelating 3-hydroxypyrimidine-2,4-diones inhibit human cytomegalovirus pUL89 endonuclease activity and virus replication.

Wang Y, Tang J, Wang Z, Geraghty RJ.

Antiviral Res. 2018 Apr;152:10-17. doi: 10.1016/j.antiviral.2018.01.015. Epub 2018 Feb 6.


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