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Items: 1 to 20 of 24


Modifying inter-cistronic sequence significantly enhances IRES dependent second gene expression in bicistronic vector: Construction of optimised cassette for gene therapy of familial hypercholesterolemia.

Al-Allaf FA, Abduljaleel Z, Athar M, Taher MM, Khan W, Mehmet H, Colakogullari M, Apostolidou S, Bigger B, Waddington S, Coutelle C, Themis M, Al-Ahdal MN, Al-Mohanna FA, Al-Hassnan ZN, Bouazzaoui A.

Noncoding RNA Res. 2018 Nov 22;4(1):1-14. doi: 10.1016/j.ncrna.2018.11.005. eCollection 2019 Mar.


Identification of six novel factor viii gene variants using next generation sequencing and molecular dynamics simulation.

Al-Allaf FA, Abduljaleel Z, Bogari NM, Owaidah TMA, Taher MM, Athar M, Elsendiony A, Abalkhail H, Abdellatif A, Elbjeirami W, Bouazzaoui A.

Acta Biochim Pol. 2019 Feb 22;66(1):23-31. doi: 10.18388/abp.2018_2339.


Novel combined variants of LDLR and LDLRAP1 genes causing severe familial hypercholesterolemia.

Alnouri F, Athar M, Al-Allaf FA, Abduljaleel Z, Taher MM, Bouazzaoui A, Al Ammari D, Karrar H, Albabtain M.

Atherosclerosis. 2018 Oct;277:425-433. doi: 10.1016/j.atherosclerosis.2018.06.878.


Molecular Analysis of Factor VIII and Factor IX Genes in Hemophilia Patients: Identification of Novel Mutations and Molecular Dynamics Studies.

Al-Allaf FA, Taher MM, Abduljaleel Z, Bouazzaoui A, Athar M, Bogari NM, Abalkhail HA, Owaidah TM.

J Clin Med Res. 2017 Apr;9(4):317-331. doi: 10.14740/jocmr2876w. Epub 2017 Feb 21.


Phytosterols as a natural anticancer agent: Current status and future perspective.

Shahzad N, Khan W, Md S, Ali A, Saluja SS, Sharma S, Al-Allaf FA, Abduljaleel Z, Ibrahim IAA, Abdel-Wahab AF, Afify MA, Al-Ghamdi SS.

Biomed Pharmacother. 2017 Apr;88:786-794. doi: 10.1016/j.biopha.2017.01.068. Epub 2017 Jan 31. Review.


Compound heterozygous LDLR variant in severely affected familial hypercholesterolemia patient.

Al-Allaf FA, Alashwal A, Abduljaleel Z, Taher MM, Bouazzaoui A, Abalkhail H, Al-Allaf AF, Athar M.

Acta Biochim Pol. 2017;64(1):75-79. doi: 10.18388/abp.2016_1283. Epub 2016 Nov 23.


Functional alterations due to amino acid changes and evolutionary comparative analysis of ARPKD and ADPKD genes.

Edrees BM, Athar M, Abduljaleel Z, Al-Allaf FA, Taher MM, Khan W, Bouazzaoui A, Al-Harbi N, Safar R, Al-Edressi H, Alansary K, Anazi A, Altayeb N, Ahmed MA.

Genom Data. 2016 Nov 3;10:127-134. eCollection 2016 Dec.


Next-generation sequencing for molecular diagnosis of autosomal recessive polycystic kidney disease.

Edrees BM, Athar M, Al-Allaf FA, Taher MM, Khan W, Bouazzaoui A, Al-Harbi N, Safar R, Al-Edressi H, Alansary K, Anazi A, Altayeb N, Ahmed MA, Abduljaleel Z.

Gene. 2016 Oct 10;591(1):214-226. doi: 10.1016/j.gene.2016.07.021. Epub 2016 Jul 9.


A Novel Four-Way Complex Variant Translocation Involving Chromosome 46,XY,t(4;9;19;22)(q25:q34;p13.3;q11.2) in a Chronic Myeloid Leukemia Patient.

Asif M, Jamal MS, Khan AR, Naseer MI, Hussain A, Choudhry H, Malik A, Khan SA, Mahmoud MM, Ali A, Iram S, Kamran K, Iqbal A, Abduljaleel Z, Pushparaj PN, Rasool M.

Front Oncol. 2016 May 30;6:124. doi: 10.3389/fonc.2016.00124. eCollection 2016.


Identification of a recurrent frameshift mutation at the LDLR exon 14 (c.2027delG, p.(G676Afs*33)) causing familial hypercholesterolemia in Saudi Arab homozygous children.

Al-Allaf FA, Alashwal A, Abduljaleel Z, Taher MM, Siddiqui SS, Bouazzaoui A, Abalkhail H, Aun R, Al-Allaf AF, AbuMansour I, Azhar Z, Ba-Hammam FA, Khan W, Athar M.

Genomics. 2016 Jan;107(1):24-32. doi: 10.1016/j.ygeno.2015.12.001. Epub 2015 Dec 11.


Next generation sequencing to identify novel genetic variants causative of autosomal dominant familial hypercholesterolemia associated with increased risk of coronary heart disease.

Al-Allaf FA, Athar M, Abduljaleel Z, Taher MM, Khan W, Ba-Hammam FA, Abalkhail H, Alashwal A.

Gene. 2015 Jul 1;565(1):76-84. doi: 10.1016/j.gene.2015.03.064. Epub 2015 Apr 1.


MWCNTs-reinforced epoxidized linseed oil plasticized polylactic acid nanocomposite and its electroactive shape memory behaviour.

Alam J, Alam M, Raja M, Abduljaleel Z, Dass LA.

Int J Mol Sci. 2014 Oct 31;15(11):19924-37. doi: 10.3390/ijms151119924.


Novel hypoxanthine guanine phosphoribosyltransferase gene mutations in Saudi Arabian hyperuricemia patients.

Alanazi M, Al-Arfaj AS, Abduljaleel Z, Fahad Al-Arfaj H, Reddy Parine N, Purusottapatnam Shaik J, Khan Z, Ali Khan Pathan A.

Biomed Res Int. 2014;2014:290325. doi: 10.1155/2014/290325. Epub 2014 Jul 9.


Evidence of trem2 variant associated with triple risk of Alzheimer's disease.

Abduljaleel Z, Al-Allaf FA, Khan W, Athar M, Shahzad N, Taher MM, Elrobh M, Alanazi MS, El-Huneidi W.

PLoS One. 2014 Mar 24;9(3):e92648. doi: 10.1371/journal.pone.0092648. eCollection 2014.


DNA mismatch repair MSH2 gene-based SNP associated with different populations.

Abduljaleel Z, Al-Allaf FA, Khan W, Athar M, Shahzad N, Taher MM, Alanazi M, Elrobh M, Reddy NP.

Mol Genet Genomics. 2014 Jun;289(3):469-87. doi: 10.1007/s00438-014-0826-4. Epub 2014 Feb 22.


Association between PARP-1 V762A polymorphism and breast cancer susceptibility in Saudi population.

Alanazi M, Pathan AA, Abduljaleel Z, Shaik JP, Alabdulkarim HA, Semlali A, Bazzi MD, Parine NR.

PLoS One. 2013 Dec 31;8(12):e85541. doi: 10.1371/journal.pone.0085541. eCollection 2013. Erratum in: PLoS One. 2014;9(3):e92360. Arifeen, Zainul [corrected to Abduljaleel, Zainularifeen].


Identification of a novel nonsense variant c.1332dup, p.(D445*) in the LDLR gene that causes familial hypercholesterolemia.

Al-Allaf FA, Athar M, Abduljaleel Z, Bouazzaoui A, Taher MM, Own R, Al-Allaf AF, AbuMansour I, Azhar Z, Ba-Hammam FA, Abalkhail H, Alashwal A.

Hum Genome Var. 2014 Nov 20;1:14021. doi: 10.1038/hgv.2014.21. eCollection 2014.


Evidence of colorectal cancer risk associated variant Lys25Ser in the proximity of human bone morphogenetic protein 2.

Khan W, Abduljaleel Z, Alanazi M, Elrobh M.

Gene. 2013 Jun 10;522(1):75-83. doi: 10.1016/j.gene.2013.03.037. Epub 2013 Mar 26. Erratum in: Gene. 2014 Jul 10;544(2):262.


Proteome Analysis of Rice (Oryza sativa L.) Mutants Reveals Differentially Induced Proteins during Brown Planthopper (Nilaparvata lugens) Infestation.

Sangha JS, Chen YH, Kaur J, Khan W, Abduljaleel Z, Alanazi MS, Mills A, Adalla CB, Bennett J, Prithiviraj B, Jahn GC, Leung H.

Int J Mol Sci. 2013 Feb 15;14(2):3921-45. doi: 10.3390/ijms14023921.


Molecular cloning, sequence analysis and expression in Escherichia coli of Camelus dromedarius glucose-6-phosphate dehydrogenase cDNA.

Saeed HM, Alanazi MS, Abduljaleel Z, Al-Amri A, Khan Z.

Protein Expr Purif. 2012 Jun;83(2):190-7. doi: 10.1016/j.pep.2012.04.004. Epub 2012 Apr 17.


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