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Items: 1 to 20 of 98


Effects of insulin signaling on mouse taste cell proliferation.

Takai S, Watanabe Y, Sanematsu K, Yoshida R, Margolskee RF, Jiang P, Atsuta I, Koyano K, Ninomiya Y, Shigemura N.

PLoS One. 2019 Nov 12;14(11):e0225190. doi: 10.1371/journal.pone.0225190. eCollection 2019.


Expression of Renin-Angiotensin System Components in the Taste Organ of Mice.

Shigemura N, Takai S, Hirose F, Yoshida R, Sanematsu K, Ninomiya Y.

Nutrients. 2019 Sep 19;11(9). pii: E2251. doi: 10.3390/nu11092251.


Fatty acid taste quality information via GPR120 in the anterior tongue of mice.

Yasumatsu K, Iwata S, Inoue M, Ninomiya Y.

Acta Physiol (Oxf). 2019 May;226(1):e13215. doi: 10.1111/apha.13215. Epub 2018 Nov 19.


Diurnal Variation of Sweet Taste Recognition Thresholds Is Absent in Overweight and Obese Humans.

Sanematsu K, Nakamura Y, Nomura M, Shigemura N, Ninomiya Y.

Nutrients. 2018 Mar 2;10(3). pii: E297. doi: 10.3390/nu10030297.


The Role of Cholecystokinin in Peripheral Taste Signaling in Mice.

Yoshida R, Shin M, Yasumatsu K, Takai S, Inoue M, Shigemura N, Takiguchi S, Nakamura S, Ninomiya Y.

Front Physiol. 2017 Oct 31;8:866. doi: 10.3389/fphys.2017.00866. eCollection 2017.


Bitter Taste Responses of Gustducin-positive Taste Cells in Mouse Fungiform and Circumvallate Papillae.

Yoshida R, Takai S, Sanematsu K, Margolskee RF, Shigemura N, Ninomiya Y.

Neuroscience. 2018 Jan 15;369:29-39. doi: 10.1016/j.neuroscience.2017.10.047. Epub 2017 Nov 4.


Sweet Taste Receptor Serves to Activate Glucose- and Leptin-Responsive Neurons in the Hypothalamic Arcuate Nucleus and Participates in Glucose Responsiveness.

Kohno D, Koike M, Ninomiya Y, Kojima I, Kitamura T, Yada T.

Front Neurosci. 2016 Nov 8;10:502. eCollection 2016.


Leptin suppresses sweet taste responses of enteroendocrine STC-1 cells.

Jyotaki M, Sanematsu K, Shigemura N, Yoshida R, Ninomiya Y.

Neuroscience. 2016 Sep 22;332:76-87. doi: 10.1016/j.neuroscience.2016.06.036. Epub 2016 Jun 25.


Enhancement of Combined Umami and Salty Taste by Glutathione in the Human Tongue and Brain.

Goto TK, Yeung AW, Tanabe HC, Ito Y, Jung HS, Ninomiya Y.

Chem Senses. 2016 Sep;41(7):623-30. doi: 10.1093/chemse/bjw066. Epub 2016 Jun 27.


Taste cell-expressed α-glucosidase enzymes contribute to gustatory responses to disaccharides.

Sukumaran SK, Yee KK, Iwata S, Kotha R, Quezada-Calvillo R, Nichols BL, Mohan S, Pinto BM, Shigemura N, Ninomiya Y, Margolskee RF.

Proc Natl Acad Sci U S A. 2016 May 24;113(21):6035-40. doi: 10.1073/pnas.1520843113. Epub 2016 May 9.


Intracellular acidification is required for full activation of the sweet taste receptor by miraculin.

Sanematsu K, Kitagawa M, Yoshida R, Nirasawa S, Shigemura N, Ninomiya Y.

Sci Rep. 2016 Mar 10;6:22807. doi: 10.1038/srep22807.


Recent Advances in Molecular Mechanisms of Taste Signaling and Modifying.

Shigemura N, Ninomiya Y.

Int Rev Cell Mol Biol. 2016;323:71-106. doi: 10.1016/bs.ircmb.2015.12.004. Epub 2016 Feb 10. Review.


Taste information derived from T1R-expressing taste cells in mice.

Yoshida R, Ninomiya Y.

Biochem J. 2016 Mar 1;473(5):525-36. doi: 10.1042/BJ20151015. Review.


Leptin Suppresses Mouse Taste Cell Responses to Sweet Compounds.

Yoshida R, Noguchi K, Shigemura N, Jyotaki M, Takahashi I, Margolskee RF, Ninomiya Y.

Diabetes. 2015 Nov;64(11):3751-62. doi: 10.2337/db14-1462. Epub 2015 Jun 26.


High resolution time-intensity recording with synchronized solution delivery system for the human dynamic taste perception.

Goto TK, Yeung AW, Suen JL, Fong BS, Ninomiya Y.

J Neurosci Methods. 2015 Apr 30;245:147-55. doi: 10.1016/j.jneumeth.2015.02.023. Epub 2015 Mar 5.


Modulation of sweet taste sensitivities by endogenous leptin and endocannabinoids in mice.

Niki M, Jyotaki M, Yoshida R, Yasumatsu K, Shigemura N, DiPatrizio NV, Piomelli D, Ninomiya Y.

J Physiol. 2015 Jun 1;593(11):2527-45. doi: 10.1113/JP270295. Epub 2015 Apr 16.


Glucagon-like peptide-1 is specifically involved in sweet taste transmission.

Takai S, Yasumatsu K, Inoue M, Iwata S, Yoshida R, Shigemura N, Yanagawa Y, Drucker DJ, Margolskee RF, Ninomiya Y.

FASEB J. 2015 Jun;29(6):2268-80. doi: 10.1096/fj.14-265355. Epub 2015 Feb 12.


Involvement of multiple taste receptors in umami taste: analysis of gustatory nerve responses in metabotropic glutamate receptor 4 knockout mice.

Yasumatsu K, Manabe T, Yoshida R, Iwatsuki K, Uneyama H, Takahashi I, Ninomiya Y.

J Physiol. 2015 Feb 15;593(4):1021-34. doi: 10.1113/jphysiol.2014.284703. Epub 2015 Jan 22.


Structure, function, and signaling of taste G-protein-coupled receptors.

Sanematsu K, Yoshida R, Shigemura N, Ninomiya Y.

Curr Pharm Biotechnol. 2014;15(10):951-61. Review.


Molecular mechanisms for sweet-suppressing effect of gymnemic acids.

Sanematsu K, Kusakabe Y, Shigemura N, Hirokawa T, Nakamura S, Imoto T, Ninomiya Y.

J Biol Chem. 2014 Sep 12;289(37):25711-20. doi: 10.1074/jbc.M114.560409. Epub 2014 Jul 23.

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