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Items: 1 to 20 of 23


Investigation of factors that cause insulin precipitation and/or amyloid formation in insulin formulations.

Ohno Y, Seki T, Kojima Y, Miki R, Egawa Y, Hosoya O, Kasono K, Seki T.

J Pharm Health Care Sci. 2019 Oct 30;5:22. doi: 10.1186/s40780-019-0151-5. eCollection 2019.


Cell Adhesive Character of Phenylboronic Acid-Modified Insulin and Its Potential as Long-Acting Insulin.

Ohno Y, Kawakami M, Seki T, Miki R, Seki T, Egawa Y.

Pharmaceuticals (Basel). 2019 Aug 19;12(3). pii: E121. doi: 10.3390/ph12030121.


Sugar-Responsive Layer-by-Layer Film Composed of Phenylboronic Acid-Appended Insulin and Poly(vinyl alcohol).

Takei C, Ohno Y, Seki T, Miki R, Seki T, Egawa Y.

Chem Pharm Bull (Tokyo). 2018;66(4):368-374. doi: 10.1248/cpb.c17-00817.


Glucose Responsive Rheological Change and Drug Release from a Novel Worm-like Micelle Gel Formed in Cetyltrimethylammonium Bromide/Phenylboronic Acid/Water System.

Miki R, Takei C, Ohtani Y, Kawashima K, Yoshida A, Kojima Y, Egawa Y, Seki T, Iohara D, Anraku M, Hirayama F, Uekama K.

Mol Pharm. 2018 Mar 5;15(3):1097-1104. doi: 10.1021/acs.molpharmaceut.7b00988. Epub 2018 Feb 7.


A Pseudopolyrotaxane for Glucose-Responsive Insulin Release: The Effect of Binding Ability and Spatial Arrangement of Phenylboronic Acid Group.

Seki T, Abe K, Egawa Y, Miki R, Juni K, Seki T.

Mol Pharm. 2016 Nov 7;13(11):3807-3815. Epub 2016 Oct 17.


Effect of Physiological Changes in the Skin on Systemic Absorption of Tacrolimus Following Topical Application in Rats.

Hazama Y, Maekawa T, Miki R, Oshima S, Egawa Y, Morimoto K, Seki T.

Biol Pharm Bull. 2016;39(3):343-52. doi: 10.1248/bpb.b15-00727.


Sugar-Responsive Pseudopolyrotaxane Composed of Phenylboronic Acid-Modified Polyethylene Glycol and γ-Cyclodextrin.

Seki T, Namiki M, Egawa Y, Miki R, Juni K, Seki T.

Materials (Basel). 2015 Mar 20;8(3):1341-1349. doi: 10.3390/ma8031341.


Development of a membrane impregnated with a poly(dimethylsiloxane)/poly(ethylene glycol) copolymer for a high-throughput screening of the permeability of drugs, cosmetics, and other chemicals across the human skin.

Miki R, Ichitsuka Y, Yamada T, Kimura S, Egawa Y, Seki T, Juni K, Ueda H, Morimoto Y.

Eur J Pharm Sci. 2015 Jan 23;66:41-9. doi: 10.1016/j.ejps.2014.09.024. Epub 2014 Oct 12.


Preparation of polypseudorotaxanes composed of cyclodextrin and polymers in microspheres.

Shinohara K, Yamashita M, Uchida W, Okabe C, Oshima S, Sugino M, Egawa Y, Miki R, Hosoya O, Fujihara T, Ishimaru Y, Kishino T, Seki T, Juni K.

Chem Pharm Bull (Tokyo). 2014;62(10):962-6.


Colorimetric Sugar Sensing Using Boronic Acid-Substituted Azobenzenes.

Egawa Y, Miki R, Seki T.

Materials (Basel). 2014 Feb 14;7(2):1201-1220. doi: 10.3390/ma7021201. Review.


[Supramolecular nanomachines for sugar responsive insulin release systems].

Egawa Y, Seki T.

Yakugaku Zasshi. 2013;133(12):1287-95. Review. Japanese.


Evaluation of the effects of absorption enhancers on Caco-2 cell monolayers by using a pore permeation model involving two different sizes.

Seki T, Hamada A, Egawa Y, Yamaki T, Uchida M, Natsume H, Kimura S, Ueda H.

Biol Pharm Bull. 2013;36(11):1862-6.


Sugar-sensitive supramolecular structures based on phenylboronic Acid-modified cyclodextrins.

Nakamura K, Seki T, Egawa Y, Miki R, Oda Y, Yamanoi T, Seki T.

Chem Pharm Bull (Tokyo). 2013;61(11):1188-91. Epub 2013 Aug 21.


Fluorometric determination of inulin using 5-quinolineboronic acid and inulinase.

Rikita T, Egawa Y, Seki T.

Anal Biochem. 2012 Jul 1;426(1):24-6. doi: 10.1016/j.ab.2012.03.029. Epub 2012 Apr 5.


The use of an artificial skin model to study transdermal absorption of drugs in inflamed skin.

Oshima S, Suzuki C, Yajima R, Egawa Y, Hosoya O, Juni K, Seki T.

Biol Pharm Bull. 2012;35(2):203-9.


[Effects of sperminated pullulans on the pulmonary absorption of insulin].

Seki T, Fukushi N, Maru H, Kimura S, Chono S, Egawa Y, Morimoto K, Ueda H, Morimoto Y.

Yakugaku Zasshi. 2011 Feb;131(2):307-14. Japanese.


Analysis of the rat skin permeation of hydrophilic compounds using the Renkin function.

Seki T, Kiuchi T, Seto H, Kimura S, Egawa Y, Ueda H, Morimoto Y.

Biol Pharm Bull. 2010;33(11):1915-8.


Fluorometric determination of heparin based on self-quenching of fluorescein-labeled protamine.

Egawa Y, Hayashida R, Seki T, Anzai J.

Talanta. 2008 Aug 15;76(4):736-41. doi: 10.1016/j.talanta.2008.04.019. Epub 2008 Apr 20.


Ortho-azo substituted phenylboronic acids for colorimetric sugar sensors.

Egawa Y, Gotoh R, Niina S, Anzai J.

Bioorg Med Chem Lett. 2007 Jul 1;17(13):3789-92. Epub 2007 Mar 3.


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