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Items: 14

1.
2.

Total Syntheses and Determination of Absolute Configurations of Cep-212 and Cep-210, Predicted Biosynthetic Intermediates of Tetrodotoxin Isolated from Toxic Newt.

Adachi M, Miyasaka T, Kudo Y, Sugimoto K, Yotsu-Yamashita M, Nishikawa T.

Org Lett. 2019 Feb 1;21(3):780-784. doi: 10.1021/acs.orglett.8b04043. Epub 2019 Jan 10.

PMID:
30628790
3.

Structural Elucidation of Trace Components Combining GC/MS, GC/IR, DFT-Calculation and Synthesis-Salinilactones, Unprecedented Bicyclic Lactones from Salinispora Bacteria.

Schlawis C, Kern S, Kudo Y, Grunenberg J, Moore BS, Schulz S.

Angew Chem Int Ed Engl. 2018 Nov 5;57(45):14921-14925. doi: 10.1002/anie.201807923. Epub 2018 Oct 15.

4.

Spiro Bicyclic Guanidino Compounds from Pufferfish: Possible Biosynthetic Intermediates of Tetrodotoxin in Marine Environments.

Ueyama N, Sugimoto K, Kudo Y, Onodera KI, Cho Y, Konoki K, Nishikawa T, Yotsu-Yamashita M.

Chemistry. 2018 May 17;24(28):7250-7258. doi: 10.1002/chem.201801006. Epub 2018 Apr 30.

PMID:
29504641
5.

Comparative transcriptomics as a guide to natural product discovery and biosynthetic gene cluster functionality.

Amos GCA, Awakawa T, Tuttle RN, Letzel AC, Kim MC, Kudo Y, Fenical W, Moore BS, Jensen PR.

Proc Natl Acad Sci U S A. 2017 Dec 26;114(52):E11121-E11130. doi: 10.1073/pnas.1714381115. Epub 2017 Dec 11.

6.

Dietary administration of tetrodotoxin and its putative biosynthetic intermediates to the captive-reared non-toxic Japanese fire-bellied newt, Cynops pyrrhogaster.

Kudo Y, Chiba C, Konoki K, Cho Y, Yotsu-Yamashita M.

Toxicon. 2017 Oct;137:78-82. doi: 10.1016/j.toxicon.2017.07.016. Epub 2017 Jul 20.

PMID:
28734983
7.

A new sarasinoside congener, sarasinoside M2, from a marine sponge collected in the Solomon Islands.

Puilingi CG, Kudo Y, Cho Y, Konoki K, Yotsu-Yamashita M.

Biosci Biotechnol Biochem. 2017 Feb;81(2):222-225. doi: 10.1080/09168451.2016.1246172. Epub 2016 Oct 20.

PMID:
27760495
8.

Cyclic Guanidine Compounds from Toxic Newts Support the Hypothesis that Tetrodotoxin is Derived from a Monoterpene.

Kudo Y, Yasumoto T, Mebs D, Cho Y, Konoki K, Yotsu-Yamashita M.

Angew Chem Int Ed Engl. 2016 Jul 18;55(30):8728-31. doi: 10.1002/anie.201602971. Epub 2016 Jun 1.

PMID:
27248052
9.
10.

Confirmation of the absence of tetrodotoxin and its analogues in the juveniles of the Japanese fire-bellied newt, Cynops pyrrhogaster, captive-reared from eggs in the laboratory using HILIC-LC-MS.

Kudo Y, Chiba C, Konoki K, Cho Y, Yotsu-Yamashita M.

Toxicon. 2015 Jul;101:101-5. doi: 10.1016/j.toxicon.2015.05.008. Epub 2015 May 16.

PMID:
25986913
11.

C5-C10 directly bonded tetrodotoxin analogues: possible biosynthetic precursors of tetrodotoxin from newts.

Kudo Y, Yamashita Y, Mebs D, Cho Y, Konoki K, Yasumoto T, Yotsu-Yamashita M.

Angew Chem Int Ed Engl. 2014 Dec 22;53(52):14546-9. doi: 10.1002/anie.201408913. Epub 2014 Nov 7.

PMID:
25382791
12.

Isolation of 6-deoxytetrodotoxin from the pufferfish, Takifugu pardalis, and a comparison of the effects of the C-6 and C-11 hydroxy groups of tetrodotoxin on its activity.

Kudo Y, Finn J, Fukushima K, Sakugawa S, Cho Y, Konoki K, Yotsu-Yamashita M.

J Nat Prod. 2014 Apr 25;77(4):1000-4. doi: 10.1021/np401097n. Epub 2014 Mar 21.

PMID:
24654947
13.

First identification of 5,11-dideoxytetrodotoxin in marine animals, and characterization of major fragment ions of tetrodotoxin and its analogs by high resolution ESI-MS/MS.

Yotsu-Yamashita M, Abe Y, Kudo Y, Ritson-Williams R, Paul VJ, Konoki K, Cho Y, Adachi M, Imazu T, Nishikawa T, Isobe M.

Mar Drugs. 2013 Aug 6;11(8):2799-813. doi: 10.3390/md11082799.

14.

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