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Items: 1 to 20 of 87


Pro-apoptotic effect of the novel benzylidene derivative MHY695 in human colon cancer cells.

Heo G, Kang D, Park C, Kim SJ, Choo J, Lee Y, Yoo JW, Jung Y, Lee J, Kim ND, Chung HY, Moon HR, Im E.

Oncol Lett. 2019 Sep;18(3):3256-3264. doi: 10.3892/ol.2019.10664. Epub 2019 Jul 25.


Colon-Targeted Delivery Facilitates the Therapeutic Switching of Sofalcone, a Gastroprotective Agent, to an Anticolitic Drug via Nrf2 Activation.

Kim W, Kim S, Ju S, Lee H, Jeong S, Yoo JW, Yoon IS, Jung Y.

Mol Pharm. 2019 Sep 3;16(9):4007-4016. doi: 10.1021/acs.molpharmaceut.9b00664. Epub 2019 Aug 16.


Pharmacokinetic Evaluation of Metabolic Drug Interactions between Repaglinide and Celecoxib by a Bioanalytical HPLC Method for Their Simultaneous Determination with Fluorescence Detection.

Han DG, Kwak J, Seo SW, Kim JM, Yoo JW, Jung Y, Lee YH, Kim MS, Jung YS, Yun H, Yoon IS.

Pharmaceutics. 2019 Aug 2;11(8). pii: E382. doi: 10.3390/pharmaceutics11080382.


PEI/NONOates-doped PLGA nanoparticles for eradicating methicillin-resistant Staphylococcus aureus biofilm in diabetic wounds via binding to the biofilm matrix.

Hasan N, Cao J, Lee J, Naeem M, Hlaing SP, Kim J, Jung Y, Lee BL, Yoo JW.

Mater Sci Eng C Mater Biol Appl. 2019 Oct;103:109741. doi: 10.1016/j.msec.2019.109741. Epub 2019 May 14.


Bacteria-Targeted Clindamycin Loaded Polymeric Nanoparticles: Effect of Surface Charge on Nanoparticle Adhesion to MRSA, Antibacterial Activity, and Wound Healing.

Hasan N, Cao J, Lee J, Hlaing SP, Oshi MA, Naeem M, Ki MH, Lee BL, Jung Y, Yoo JW.

Pharmaceutics. 2019 May 15;11(5). pii: E236. doi: 10.3390/pharmaceutics11050236.


Mesalazine activates adenosine monophosphate-activated protein kinase: Implication in the anti-inflammatory activity of this anti-colitic drug.

Park H, Kim W, Kim D, Jeong S, Jung Y.

Curr Mol Pharmacol. 2019 Mar 7. doi: 10.2174/1874467212666190308103448. [Epub ahead of print]


A colon-specific prodrug of metoclopramide ameliorates colitis in an experimental rat model.

Yang Y, Kim W, Kim D, Jeong S, Yoo JW, Jung Y.

Drug Des Devel Ther. 2018 Dec 28;13:231-242. doi: 10.2147/DDDT.S185257. eCollection 2019.


Therapeutic switching of sulpiride, an anti-psychotic and prokinetic drug, to an anti-colitic drug using colon-specific drug delivery.

Kim D, Kim W, Jeong S, Kim D, Yoo JW, Jung Y.

Drug Deliv Transl Res. 2019 Feb;9(1):334-343. doi: 10.1007/s13346-018-00599-7.


S-Nitrosoglutathione loaded poly(lactic-co-glycolic acid) microparticles for prolonged nitric oxide release and enhanced healing of methicillin-resistant Staphylococcus aureus-infected wounds.

Hlaing SP, Kim J, Lee J, Hasan N, Cao J, Naeem M, Lee EH, Shin JH, Jung Y, Lee BL, Jhun BH, Yoo JW.

Eur J Pharm Biopharm. 2018 Nov;132:94-102. doi: 10.1016/j.ejpb.2018.09.009. Epub 2018 Sep 14.


Novel β-phenylacrylic acid derivatives exert anti-cancer activity by inducing Src-mediated apoptosis in wild-type KRAS colon cancer.

Kim SJ, Noh TH, Son S, Kim DH, Kim W, Lee Y, Choo J, Heo G, Kim MJ, Chung HY, Jung Y, Jung JH, Moon HR, Im E.

Cell Death Dis. 2018 Aug 29;9(9):877. doi: 10.1038/s41419-018-0942-x.


Colon-targeted dexamethasone microcrystals with pH-sensitive chitosan/alginate/Eudragit S multilayers for the treatment of inflammatory bowel disease.

Oshi MA, Naeem M, Bae J, Kim J, Lee J, Hasan N, Kim W, Im E, Jung Y, Yoo JW.

Carbohydr Polym. 2018 Oct 15;198:434-442. doi: 10.1016/j.carbpol.2018.06.107. Epub 2018 Jun 26.


Is it worth expending energy to convert biliverdin into bilirubin?

Nam J, Lee Y, Yang Y, Jeong S, Kim W, Yoo JW, Moon JO, Lee C, Chung HY, Kim MS, Jon S, Jung Y.

Free Radic Biol Med. 2018 Aug 20;124:232-240. doi: 10.1016/j.freeradbiomed.2018.06.010. Epub 2018 Jun 10.


Colon-targeted delivery of cyclosporine A using dual-functional Eudragit® FS30D/PLGA nanoparticles ameliorates murine experimental colitis.

Naeem M, Bae J, Oshi MA, Kim MS, Moon HR, Lee BL, Im E, Jung Y, Yoo JW.

Int J Nanomedicine. 2018 Feb 28;13:1225-1240. doi: 10.2147/IJN.S157566. eCollection 2018.


pH-triggered surface charge-reversal nanoparticles alleviate experimental murine colitis via selective accumulation in inflamed colon regions.

Naeem M, Oshi MA, Kim J, Lee J, Cao J, Nurhasni H, Im E, Jung Y, Yoo JW.

Nanomedicine. 2018 Apr;14(3):823-834. doi: 10.1016/j.nano.2018.01.003. Epub 2018 Jan 17.


Minoxidil Induction of VEGF Is Mediated by Inhibition of HIF-Prolyl Hydroxylase.

Yum S, Jeong S, Kim D, Lee S, Kim W, Yoo JW, Kim JA, Kwon OS, Kim DD, Min DS, Jung Y.

Int J Mol Sci. 2017 Dec 25;19(1). pii: E53. doi: 10.3390/ijms19010053.


Insecticidal activity of the metalloprotease AprA occurs through suppression of host cellular and humoral immunity.

Lee SA, Jang SH, Kim BH, Shibata T, Yoo J, Jung Y, Kawabata SI, Lee BL.

Dev Comp Immunol. 2018 Apr;81:116-126. doi: 10.1016/j.dci.2017.11.014. Epub 2017 Nov 23.


Oxidized 5-aminosalicylic acid activates Nrf2-HO-1 pathway by covalently binding to Keap1: Implication in anti-inflammatory actions of 5-aminosalicylic acid.

Kang S, Kim W, Jeong S, Lee Y, Nam J, Lee S, Jung Y.

Free Radic Biol Med. 2017 Jul;108:715-724. doi: 10.1016/j.freeradbiomed.2017.04.366. Epub 2017 May 1.


Conjugation of metronidazole with dextran: a potential pharmaceutical strategy to control colonic distribution of the anti-amebic drug susceptible to metabolism by colonic microbes.

Kim W, Yang Y, Kim D, Jeong S, Yoo JW, Yoon JH, Jung Y.

Drug Des Devel Ther. 2017 Feb 14;11:419-429. doi: 10.2147/DDDT.S129922. eCollection 2017.


Rebamipide induces the gastric mucosal protective factor, cyclooxygenase-2, via activation of 5'-AMP-activated protein kinase.

Lee S, Jeong S, Kim W, Kim D, Yang Y, Yoon JH, Kim BJ, Min DS, Jung Y.

Biochem Biophys Res Commun. 2017 Jan 29;483(1):449-455. doi: 10.1016/j.bbrc.2016.12.123. Epub 2016 Dec 21.


Increased therapeutic efficacy of a newly synthesized tyrosinase inhibitor by solid lipid nanoparticles in the topical treatment of hyperpigmentation.

Al-Amin M, Cao J, Naeem M, Banna H, Kim MS, Jung Y, Chung HY, Moon HR, Yoo JW.

Drug Des Devel Ther. 2016 Dec 2;10:3947-3957. eCollection 2016.

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