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Items: 16


Heterozygous variant fibrinogen γA289V (Kanazawa III) was confirmed as hypodysfibrinogenemia by plasma and recombinant fibrinogens.

Kaido T, Yoda M, Kamijo T, Taira C, Higuchi Y, Okumura N.

Int J Lab Hematol. 2020 Apr;42(2):190-197. doi: 10.1111/ijlh.13152. Epub 2020 Jan 20.


In Vivo Administration of Recombinant Human Granulocyte Colony-Stimulating Factor Increases the Immune Effectiveness of Dendritic Cell-Based Cancer Vaccination.

Shimodaira S, Yanagisawa R, Koya T, Hirabayashi K, Higuchi Y, Sakamoto T, Togi M, Kato T Jr, Kobayashi T, Koizumi T, Koido S, Sugiyama H.

Vaccines (Basel). 2019 Sep 19;7(3). pii: E120. doi: 10.3390/vaccines7030120.


γD318Y fibrinogen shows no fibrin polymerization due to defective "A-a" and "B-b" interactions, whereas that of γK321E fibrinogen is nearly normal.

Kamijo T, Mukai S, Taira C, Higuchi Y, Okumura N.

Thromb Res. 2019 Oct;182:150-158. doi: 10.1016/j.thromres.2019.08.017. Epub 2019 Aug 20.


Leaf shape deters plant processing by an herbivorous weevil.

Higuchi Y, Kawakita A.

Nat Plants. 2019 Sep;5(9):959-964. doi: 10.1038/s41477-019-0505-x. Epub 2019 Sep 2.


Fibrin monomers derived from thrombogenic dysfibrinogenemia, Naples-type variant (BβAla68Thr), showed almost entirely normal polymerization.

Kamijo T, Nagata K, Taira C, Higuchi Y, Arai S, Okumura N.

Thromb Res. 2018 Dec;172:1-3. doi: 10.1016/j.thromres.2018.10.004. Epub 2018 Oct 4. No abstract available.


Feasibility and Immune Response of WT1 Peptide Vaccination in Combination with OK-432 for Paediatric Solid Tumors.

Hirabayashi K, Yanagisawa R, Saito S, Higuchi Y, Koya T, Sano K, Koido S, Okamoto M, Sugiyama H, Nakazawa Y, Shimodaira S.

Anticancer Res. 2018 Apr;38(4):2227-2234.


Interferon-α-inducible Dendritic Cells Matured with OK-432 Exhibit TRAIL and Fas Ligand Pathway-mediated Killer Activity.

Koya T, Yanagisawa R, Higuchi Y, Sano K, Shimodaira S.

Sci Rep. 2017 Feb 13;7:42145. doi: 10.1038/srep42145.


Dendritic Cell-Based Cancer Immunotherapy Targeting Wilms’ Tumor 1 for Pediatric Cancer.

Shimodaira S, Hirabayashi K, Yanagisawa R, Higuchi Y, Sano K, Koizumi T.

In: van den Heuvel-Eibrink MM, editor. Wilms Tumor [Internet]. Brisbane (AU): Codon Publications; 2016 Mar. Chapter 8.


Dendritic Cell-Based Adjuvant Vaccination Targeting Wilms' Tumor 1 in Patients with Advanced Colorectal Cancer.

Shimodaira S, Sano K, Hirabayashi K, Koya T, Higuchi Y, Mizuno Y, Yamaoka N, Yuzawa M, Kobayashi T, Ito K, Koizumi T.

Vaccines (Basel). 2015 Dec 11;3(4):1004-18. doi: 10.3390/vaccines3041004.


Enzyme-Linked Immunosorbent Spot Assay for the Detection of Wilms' Tumor 1-Specific T Cells Induced by Dendritic Cell Vaccination.

Higuchi Y, Koya T, Yuzawa M, Yamaoka N, Mizuno Y, Yoshizawa K, Hirabayashi K, Kobayashi T, Sano K, Shimodaira S.

Biomedicines. 2015 Dec 4;3(4):304-315. doi: 10.3390/biomedicines3040304.


Dendritic cell-based immunotherapy targeting Wilms' tumor 1 in patients with recurrent malignant glioma.

Sakai K, Shimodaira S, Maejima S, Udagawa N, Sano K, Higuchi Y, Koya T, Ochiai T, Koide M, Uehara S, Nakamura M, Sugiyama H, Yonemitsu Y, Okamoto M, Hongo K.

J Neurosurg. 2015 Oct;123(4):989-97. doi: 10.3171/2015.1.JNS141554. Epub 2015 Aug 7.


Safety and tolerability of allogeneic dendritic cell vaccination with induction of Wilms tumor 1-specific T cells in a pediatric donor and pediatric patient with relapsed leukemia: a case report and review of the literature.

Saito S, Yanagisawa R, Yoshikawa K, Higuchi Y, Koya T, Yoshizawa K, Tanaka M, Sakashita K, Kobayashi T, Kurata T, Hirabayashi K, Nakazawa Y, Shiohara M, Yonemitsu Y, Okamoto M, Sugiyama H, Koike K, Shimodaira S.

Cytotherapy. 2015 Mar;17(3):330-5. doi: 10.1016/j.jcyt.2014.10.003. Epub 2014 Dec 4.


A case of Behcet's disease associated with myelodysplastic syndrome involving trisomy 8 and a gain-of-function mutation in SHP-2.

Shigemura T, Agematsu K, Yamazaki T, Sakashita K, Nakayama Y, Higuchi Y, Matsuda K, Koike K.

Rheumatology (Oxford). 2011 Jul;50(7):1342-4. doi: 10.1093/rheumatology/ker137. Epub 2011 Apr 10. No abstract available.


CD20-negative CD138-positive leukemic large cell lymphoma with plasmablastic differentiation with an IgH/MYC translocation in an HIV-positive patient.

Yotsumoto M, Ichikawa N, Ueno M, Higuchi Y, Asano N, Kobayashi H.

Intern Med. 2009;48(7):559-62. Epub 2009 Apr 1.


Simple polymerase chain reaction for the detection of mutations and deletions in the epidermal growth factor receptor gene: applications of this method for the diagnosis of non-small-cell lung cancer.

Uhara M, Matsuda K, Taira C, Higuchi Y, Okumura N, Yamauchi K.

Clin Chim Acta. 2009 Mar;401(1-2):68-72. doi: 10.1016/j.cca.2008.11.018. Epub 2008 Nov 24.


[Additional chromosomal changes in impaired chimeric analysis of a patient with relapsed leukemia after bone marrow transplantation].

Higuchi Y, Ito T, Matsuda K, Higuchi T, Hidaka E, Imagawa E, Uhara M, Nakazawa H, Ishida F, Yamauchi K, Sano K, Katsuyama T.

Rinsho Ketsueki. 2008 Feb;49(2):109-14. Japanese.


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