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Items: 1 to 20 of 32

1.

KIF20A, highly expressed in immature hematopoietic cells, supports the growth of HL60 cell line.

Morita H, Matsuoka A, Kida JI, Tabata H, Tohyama K, Tohyama Y.

Int J Hematol. 2018 Dec;108(6):607-614. doi: 10.1007/s12185-018-2527-y. Epub 2018 Sep 4.

PMID:
30182171
2.

An MDS-derived cell line and a series of its sublines serve as an in vitro model for the leukemic evolution of MDS.

Kida JI, Tsujioka T, Suemori SI, Okamoto S, Sakakibara K, Takahata T, Yamauchi T, Kitanaka A, Tohyama Y, Tohyama K.

Leukemia. 2018 Aug;32(8):1846-1850. doi: 10.1038/s41375-018-0189-7. Epub 2018 Jun 28. No abstract available.

PMID:
29955132
3.

Glycosaminoglycan Binding and Non-Endocytic Membrane Translocation of Cell-Permeable Octaarginine Monitored by Real-Time In-Cell NMR Spectroscopy.

Takechi-Haraya Y, Aki K, Tohyama Y, Harano Y, Kawakami T, Saito H, Okamura E.

Pharmaceuticals (Basel). 2017 Apr 15;10(2). pii: E42. doi: 10.3390/ph10020042.

4.

Withaferin A suppresses the growth of myelodysplasia and leukemia cell lines by inhibiting cell cycle progression.

Okamoto S, Tsujioka T, Suemori S, Kida J, Kondo T, Tohyama Y, Tohyama K.

Cancer Sci. 2016 Sep;107(9):1302-14. doi: 10.1111/cas.12988. Epub 2016 Jul 28.

5.

Five-aza-2'-deoxycytidine-induced hypomethylation of cholesterol 25-hydroxylase gene is responsible for cell death of myelodysplasia/leukemia cells.

Tsujioka T, Yokoi A, Itano Y, Takahashi K, Ouchida M, Okamoto S, Kondo T, Suemori S, Tohyama Y, Tohyama K.

Sci Rep. 2015 Nov 18;5:16709. doi: 10.1038/srep16709.

6.

Salbutamol inhibits ubiquitin-mediated survival motor neuron protein degradation in spinal muscular atrophy cells.

Harahap NIF, Nurputra DK, Ar Rochmah M, Shima A, Morisada N, Takarada T, Takeuchi A, Tohyama Y, Yanagisawa S, Nishio H.

Biochem Biophys Rep. 2015 Oct 28;4:351-356. doi: 10.1016/j.bbrep.2015.10.012. eCollection 2015 Dec.

7.

Suppressive effect of membrane-permeable peptides derived from autophosphorylation sites of the IGF-1 receptor on breast cancer cells.

Kuroda Y, Kato-Kogoe N, Tasaki E, Yuasa-Sunagawa M, Yamanegi K, Nakasho K, Nakase I, Futaki S, Tohyama Y, Hirose M.

Eur J Pharmacol. 2015 Oct 15;765:24-33. doi: 10.1016/j.ejphar.2015.08.004. Epub 2015 Aug 12. Erratum in: Eur J Pharmacol. 2015 Nov 15;767:220. Nakase, Ikuhiko [corrected to Nakasho, Ikuhiko].

PMID:
26276395
8.

Rab27a is essential for the formation of neutrophil extracellular traps (NETs) in neutrophil-like differentiated HL60 cells.

Kawakami T, He J, Morita H, Yokoyama K, Kaji H, Tanaka C, Suemori S, Tohyama K, Tohyama Y.

PLoS One. 2014 Jan 3;9(1):e84704. doi: 10.1371/journal.pone.0084704. eCollection 2014.

9.

Intragenic mutations in SMN1 may contribute more significantly to clinical severity than SMN2 copy numbers in some spinal muscular atrophy (SMA) patients.

Yamamoto T, Sato H, Lai PS, Nurputra DK, Harahap NI, Morikawa S, Nishimura N, Kurashige T, Ohshita T, Nakajima H, Yamada H, Nishida Y, Toda S, Takanashi J, Takeuchi A, Tohyama Y, Kubo Y, Saito K, Takeshima Y, Matsuo M, Nishio H.

Brain Dev. 2014 Nov;36(10):914-20. doi: 10.1016/j.braindev.2013.11.009. Epub 2013 Dec 17.

PMID:
24359787
10.

Spinal muscular atrophy: from gene discovery to clinical trials.

Nurputra DK, Lai PS, Harahap NI, Morikawa S, Yamamoto T, Nishimura N, Kubo Y, Takeuchi A, Saito T, Takeshima Y, Tohyama Y, Tay SK, Low PS, Saito K, Nishio H.

Ann Hum Genet. 2013 Sep;77(5):435-63. doi: 10.1111/ahg.12031. Epub 2013 Jul 23. Review.

11.

Tubulin polymerization-promoting protein (TPPP/p25α) promotes unconventional secretion of α-synuclein through exophagy by impairing autophagosome-lysosome fusion.

Ejlerskov P, Rasmussen I, Nielsen TT, Bergström AL, Tohyama Y, Jensen PH, Vilhardt F.

J Biol Chem. 2013 Jun 14;288(24):17313-35. doi: 10.1074/jbc.M112.401174. Epub 2013 Apr 29.

12.

Effects of DNA methyltransferase inhibitors (DNMTIs) on MDS-derived cell lines.

Tsujioka T, Yokoi A, Uesugi M, Kishimoto M, Tochigi A, Suemori S, Tohyama Y, Tohyama K.

Exp Hematol. 2013 Feb;41(2):189-97. doi: 10.1016/j.exphem.2012.10.006. Epub 2012 Oct 17.

PMID:
23085465
13.

Oligopeptides derived from autophosphorylation sites of EGF receptor suppress EGF-stimulated responses in human lung carcinoma A549 cells.

Kuroda Y, Kato-Kogoe N, Tasaki E, Murata E, Ueda K, Abe M, Miyamoto K, Nakase I, Futaki S, Tohyama Y, Hirose M.

Eur J Pharmacol. 2013 Jan 5;698(1-3):87-94. doi: 10.1016/j.ejphar.2012.10.007. Epub 2012 Oct 17.

PMID:
23085023
14.

Approach to new therapeutics: investigation by the use of MDS-derived cell lines.

Tsujioka T, Matsuoka A, Tohyama Y, Tohyama K.

Curr Pharm Des. 2012;18(22):3204-14. Review.

PMID:
22571700
15.

Rab27b regulates c-kit expression by controlling the secretion of stem cell factor.

Tanaka C, Kaji H, He J, Hazama R, Yokoyama K, Kinoshita E, Tsujioka T, Tohyama K, Yamamura H, Nishio H, Tohyama Y.

Biochem Biophys Res Commun. 2012 Mar 9;419(2):368-73. doi: 10.1016/j.bbrc.2012.02.030. Epub 2012 Feb 13.

PMID:
22349512
16.

Rab27a negatively regulates phagocytosis by prolongation of the actin-coating stage around phagosomes.

Yokoyama K, Kaji H, He J, Tanaka C, Hazama R, Kamigaki T, Ku Y, Tohyama K, Tohyama Y.

J Biol Chem. 2011 Feb 18;286(7):5375-82. doi: 10.1074/jbc.M110.171702. Epub 2010 Dec 18.

17.

Protein kinase C {delta}-specific activity reporter reveals agonist-evoked nuclear activity controlled by Src family of kinases.

Kajimoto T, Sawamura S, Tohyama Y, Mori Y, Newton AC.

J Biol Chem. 2010 Dec 31;285(53):41896-910. doi: 10.1074/jbc.M110.184028. Epub 2010 Oct 19.

18.

ATP-induced osteoclast function: the formation of sealing-zone like structure and the secretion of lytic granules via microtubule-deacetylation under the control of Syk.

Hazama R, Qu X, Yokoyama K, Tanaka C, Kinoshita E, He J, Takahashi S, Tohyama K, Yamamura H, Tohyama Y.

Genes Cells. 2009 Jul;14(7):871-84. doi: 10.1111/j.1365-2443.2009.01317.x. Epub 2009 Jun 22.

19.

Protein tyrosine kinase, syk: a key player in phagocytic cells.

Tohyama Y, Yamamura H.

J Biochem. 2009 Mar;145(3):267-73. doi: 10.1093/jb/mvp001. Epub 2009 Jan 4. Review.

PMID:
19124456
20.

Validation of the revised 2008 WHO diagnostic criteria in 75 suspected cases of myeloproliferative neoplasm.

Kondo T, Okuno N, Naruse H, Kishimoto M, Tasaka T, Tsujioka T, Matsuoka A, Sugihara T, Tohyama Y, Tohyama K.

Leuk Lymphoma. 2008 Sep;49(9):1784-91. doi: 10.1080/10428190802258972.

PMID:
18661406

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