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Fexofenadine inhibits TNF signaling through targeting to cytosolic phospholipase A2 and is therapeutic against inflammatory arthritis.

Liu R, Chen Y, Fu W, Wang S, Cui Y, Zhao X, Lei ZN, Hettinghouse A, Liu J, Wang C, Zhang C, Bi Y, Xiao G, Chen ZS, Liu CJ.

Ann Rheum Dis. 2019 Jul 13. pii: annrheumdis-2019-215543. doi: 10.1136/annrheumdis-2019-215543. [Epub ahead of print]


Rational Design of Zika Virus Subunit Vaccine with Enhanced Efficacy.

Tai W, Chen J, Zhao G, Geng Q, He L, Chen Y, Zhou Y, Li F, Du L.

J Virol. 2019 Aug 13;93(17). pii: e02187-18. doi: 10.1128/JVI.02187-18. Print 2019 Sep 1.


Enhanced Ability of Oligomeric Nanobodies Targeting MERS Coronavirus Receptor-Binding Domain.

He L, Tai W, Li J, Chen Y, Gao Y, Li J, Sun S, Zhou Y, Du L, Zhao G.

Viruses. 2019 Feb 19;11(2). pii: E166. doi: 10.3390/v11020166.


Clinical Application of Teriparatide in Fracture Prevention: A Systematic Review.

Chen Y, Liu R, Hettinghouse A, Wang S, Liu G, Liu CJ.

JBJS Rev. 2019 Jan;7(1):e10. doi: 10.2106/JBJS.RVW.18.00052.


Complement Receptor C5aR1 Inhibition Reduces Pyroptosis in hDPP4-Transgenic Mice Infected with MERS-CoV.

Jiang Y, Li J, Teng Y, Sun H, Tian G, He L, Li P, Chen Y, Guo Y, Li J, Zhao G, Zhou Y, Sun S.

Viruses. 2019 Jan 9;11(1). pii: E39. doi: 10.3390/v11010039.


Fragment-based drug discovery of triazole inhibitors to block PDE╬┤-RAS protein-protein interaction.

Chen D, Chen Y, Lian F, Chen L, Li Y, Cao D, Wang X, Chen L, Li J, Meng T, Huang M, Geng M, Shen J, Zhang N, Xiong B.

Eur J Med Chem. 2019 Feb 1;163:597-609. doi: 10.1016/j.ejmech.2018.12.018. Epub 2018 Dec 11.


A Positive Feedback Loop of SLP2 Activates MAPK Signaling Pathway to Promote Gastric Cancer Progression.

Ma W, Xu Z, Wang Y, Li W, Wei Z, Chen T, Mou T, Cheng M, Luo J, Luo T, Chen Y, Yu J, Zhou W, Li G.

Theranostics. 2018 Nov 10;8(20):5744-5757. doi: 10.7150/thno.28898. eCollection 2018.


[Progress in conversion therapy for originally unresectable gastric cancer].

Chen X, Lin Z, Chen Y, Luo J, Zhu Y, Liu H, Li G, Yu J.

Zhonghua Wei Chang Wai Ke Za Zhi. 2018 Oct 25;21(10):1191-1195. Review. Chinese.


Progranulin associates with hexosaminidase A and ameliorates GM2 ganglioside accumulation and lysosomal storage in Tay-Sachs disease.

Chen Y, Jian J, Hettinghouse A, Zhao X, Setchell KDR, Sun Y, Liu CJ.

J Mol Med (Berl). 2018 Dec;96(12):1359-1373. doi: 10.1007/s00109-018-1703-0. Epub 2018 Oct 20.


[Surgical safety of laparoscopic total gastrectomy with intracorporeal esophagojejunostomy via transoral anvil versus mini-laparotomy anastomosis: a propensity score matching analysis].

Chen X, Luo J, Zhu Y, Chen Y, Hu Y, Lin T, Liu H, Li T, Zhao M, Chen H, Li G, Yu J.

Zhonghua Wei Chang Wai Ke Za Zhi. 2018 Aug 25;21(8):887-895. Chinese.


A Novel Nanobody Targeting Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Receptor-Binding Domain Has Potent Cross-Neutralizing Activity and Protective Efficacy against MERS-CoV.

Zhao G, He L, Sun S, Qiu H, Tai W, Chen J, Li J, Chen Y, Guo Y, Wang Y, Shang J, Ji K, Fan R, Du E, Jiang S, Li F, Du L, Zhou Y.

J Virol. 2018 Aug 29;92(18). pii: e00837-18. doi: 10.1128/JVI.00837-18. Print 2018 Sep 15.


[Progress in prophylatic hyperthermic intraperitoneal chemotherapy for advanced gastric carcinoma].

Chen X, Luo J, Liu H, Chen Y, Hu Y, Li T, Lin T, Zhu Y, Zhao M, Chen H, Li G, Yu J.

Zhonghua Wei Chang Wai Ke Za Zhi. 2018 May 25;21(5):593-599. Review. Chinese.


Molecular regulations and therapeutic targets of Gaucher disease.

Chen Y, Sud N, Hettinghouse A, Liu CJ.

Cytokine Growth Factor Rev. 2018 Jun;41:65-74. doi: 10.1016/j.cytogfr.2018.04.003. Epub 2018 Apr 11. Review.


Blockade of the C5a-C5aR axis alleviates lung damage in hDPP4-transgenic mice infected with MERS-CoV.

Jiang Y, Zhao G, Song N, Li P, Chen Y, Guo Y, Li J, Du L, Jiang S, Guo R, Sun S, Zhou Y.

Emerg Microbes Infect. 2018 Apr 24;7(1):77. doi: 10.1038/s41426-018-0063-8.


C5a receptor1 inhibition alleviates influenza virus-induced acute lung injury.

Song N, Li P, Jiang Y, Sun H, Cui J, Zhao G, Li D, Guo Y, Chen Y, Gao J, Sun S, Zhou Y.

Int Immunopharmacol. 2018 Jun;59:12-20. doi: 10.1016/j.intimp.2018.03.029. Epub 2018 Apr 2.


Associations between gene polymorphisms and treatment outcomes of methotrexate in patients with juvenile idiopathic arthritis.

Chen Y, Zou K, Sun J, Yang Y, Liu G.

Pharmacogenomics. 2018 Apr;19(6):529-538. doi: 10.2217/pgs-2017-0208. Epub 2018 Mar 28.


Diagnostic value of WIF1 methylation for colorectal cancer: a meta-analysis.

Hu H, Li B, Zhou C, Ying X, Chen M, Huang T, Chen Y, Ji H, Pan R, Wang T, Jiang D, Chen Y, Yang Y, Duan S.

Oncotarget. 2018 Jan 3;9(4):5378-5386. doi: 10.18632/oncotarget.23870. eCollection 2018 Jan 12.


Chitinase-3-like Protein 1: A Progranulin Downstream Molecule and Potential Biomarker for Gaucher Disease.

Jian J, Chen Y, Liberti R, Fu W, Hu W, Saunders-Pullman R, Pastores GM, Chen Y, Sun Y, Grabowski GA, Liu CJ.

EBioMedicine. 2018 Feb;28:251-260. doi: 10.1016/j.ebiom.2018.01.022. Epub 2018 Jan 31.


Treatment for lupus nephritis: an overview of systematic reviews and meta-analyses.

Chen Y, Sun J, Zou K, Yang Y, Liu G.

Rheumatol Int. 2017 Jul;37(7):1089-1099. doi: 10.1007/s00296-017-3733-2. Epub 2017 May 10. Review.


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