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Items: 1 to 20 of 55


Discovery of novel dual-active 3-(4-(dimethylamino)phenyl)-7-aminoalcoxy-coumarin as potent and selective acetylcholinesterase inhibitor and antioxidant.

de Souza GA, da Silva SJ, Del Cistia CN, Pitasse-Santos P, Pires LO, Passos YM, Cordeiro Y, Cardoso CM, Castro RN, Sant'Anna CMR, Kümmerle AE.

J Enzyme Inhib Med Chem. 2019 Dec;34(1):631-637. doi: 10.1080/14756366.2019.1571270.


Association of high pressure and alkaline condition for solubilization of inclusion bodies and refolding of the NS1 protein from zika virus.

Rosa da Silva CM, Chura-Chambi RM, Ramos Pereira L, Cordeiro Y, de Souza Ferreira LC, Morganti L.

BMC Biotechnol. 2018 Dec 12;18(1):78. doi: 10.1186/s12896-018-0486-2.


Design, synthesis, structural characterization and in vitro evaluation of new 1,4-disubstituted-1,2,3-triazole derivatives against glioblastoma cells.

da Silva VD, de Faria BM, Colombo E, Ascari L, Freitas GPA, Flores LS, Cordeiro Y, Romão L, Buarque CD.

Bioorg Chem. 2018 Oct 11;83:87-97. doi: 10.1016/j.bioorg.2018.10.003. [Epub ahead of print]


Publish and perish in the hands of predatory journals.

Cordeiro Y, Lima LMTR.

An Acad Bras Cienc. 2017 Apr-Jun;89(2):787-788. doi: 10.1590/0001-37652017892. No abstract available.


Unraveling Prion Protein Interactions with Aptamers and Other PrP-Binding Nucleic Acids.

Macedo B, Cordeiro Y.

Int J Mol Sci. 2017 May 17;18(5). pii: E1023. doi: 10.3390/ijms18051023. Review.


Distinct modulatory role of RNA in the aggregation of the tumor suppressor protein p53 core domain.

Kovachev PS, Banerjee D, Rangel LP, Eriksson J, Pedrote MM, Martins-Dinis MMDC, Edwards K, Cordeiro Y, Silva JL, Sanyal S.

J Biol Chem. 2017 Jun 2;292(22):9345-9357. doi: 10.1074/jbc.M116.762096. Epub 2017 Apr 18.


Structural basis for the dissociation of α-synuclein fibrils triggered by pressure perturbation of the hydrophobic core.

de Oliveira GA, Marques MA, Cruzeiro-Silva C, Cordeiro Y, Schuabb C, Moraes AH, Winter R, Oschkinat H, Foguel D, Freitas MS, Silva JL.

Sci Rep. 2016 Nov 30;6:37990. doi: 10.1038/srep37990.


Virtual drug screening for prion diseases: A valuable step?

Cordeiro Y.

EBioMedicine. 2016 Jul;9:15-16. doi: 10.1016/j.ebiom.2016.06.043. Epub 2016 Jun 30. No abstract available.


Nanoencapsulated Lecitase Ultra and Thermomyces lanuginosus Lipase, a Comparative Structural Study.

Gonçalves KM, Junior II, Papadimitriou V, Zoumpanioti M, Leal IC, de Souza RO, Cordeiro Y, Xenakis A.

Langmuir. 2016 Jul 5;32(26):6746-56. doi: 10.1021/acs.langmuir.6b00826. Epub 2016 Jun 23.


The "Jekyll and Hyde" Actions of Nucleic Acids on the Prion-like Aggregation of Proteins.

Silva JL, Cordeiro Y.

J Biol Chem. 2016 Jul 22;291(30):15482-90. doi: 10.1074/jbc.R116.733428. Epub 2016 Jun 10. Review.


Mammalian prion amyloid formation in bacteria.

Macedo B, Cordeiro Y, Ventura S.

Prion. 2016 Mar 3;10(2):112-8. doi: 10.1080/19336896.2016.1141859.


Mammalian prion protein (PrP) forms conformationally different amyloid intracellular aggregates in bacteria.

Macedo B, Sant'Anna R, Navarro S, Cordeiro Y, Ventura S.

Microb Cell Fact. 2015 Nov 4;14:174. doi: 10.1186/s12934-015-0361-y.


Hot Topics in Biomedical Sciences.

Cordeiro Y, Schuck PF.

An Acad Bras Cienc. 2015 Aug;87(2 Suppl):1271-2. doi: 10.1590/0001-376520158722. No abstract available.


Biophysical Studies on BEX3, the p75NTR-Associated Cell Death Executor, Reveal a High-Order Oligomer with Partially Folded Regions.

Cabral KM, Raymundo DP, Silva VS, Sampaio LA, Johanson L, Hill LF, Almeida FC, Cordeiro Y, Almeida MS.

PLoS One. 2015 Sep 18;10(9):e0137916. doi: 10.1371/journal.pone.0137916. eCollection 2015.


Toxicological Evaluation of Anti-Scrapie Trimethoxychalcones and Oxadiazoles.

Figueiredo CP, Ferreira NC, Passos GF, Costa Rd, Neves FS, Machado CS, Mascarello A, Chiaradia-Delatorre LD, Neuenfeldt PD, Nunes RJ, Cordeiro Y.

An Acad Bras Cienc. 2015 Aug;87(2 Suppl):1421-34. doi: 10.1590/0001-3765201520140712. Epub 2015 Aug 4.


New approaches for the selection and evaluation of anti-prion organic compounds.

Cordeiro Y, Ferreira NC.

Mini Rev Med Chem. 2015;15(2):84-92. Review.


Stability and structural changes of horseradish peroxidase: microwave versus conventional heating treatment.

Lopes LC, Barreto MT, Gonçalves KM, Alvarez HM, Heredia MF, de Souza RO, Cordeiro Y, Dariva C, Fricks AT.

Enzyme Microb Technol. 2015 Feb;69:10-8. doi: 10.1016/j.enzmictec.2014.11.002. Epub 2014 Nov 24.


The importance of a gatekeeper residue on the aggregation of transthyretin: implications for transthyretin-related amyloidoses.

Sant'Anna R, Braga C, Varejão N, Pimenta KM, Graña-Montes R, Alves A, Cortines J, Cordeiro Y, Ventura S, Foguel D.

J Biol Chem. 2014 Oct 10;289(41):28324-37. doi: 10.1074/jbc.M114.563981. Epub 2014 Aug 1.


Heparin binding confers prion stability and impairs its aggregation.

Vieira TC, Cordeiro Y, Caughey B, Silva JL.

FASEB J. 2014 Jun;28(6):2667-76. doi: 10.1096/fj.13-246777. Epub 2014 Mar 19.


Pathological implications of nucleic acid interactions with proteins associated with neurodegenerative diseases.

Cordeiro Y, Macedo B, Silva JL, Gomes MPB.

Biophys Rev. 2014 Mar;6(1):97-110. doi: 10.1007/s12551-013-0132-0. Epub 2014 Jan 9. Review.

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