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Items: 1 to 20 of 43


Sec17 (α-SNAP) and Sec18 (NSF) restrict membrane fusion to R-SNAREs, Q-SNAREs, and SM proteins from identical compartments.

Jun Y, Wickner W.

Proc Natl Acad Sci U S A. 2019 Nov 19;116(47):23573-23581. doi: 10.1073/pnas.1913985116. Epub 2019 Nov 4.


Quaternary structures of Vac8 differentially regulate the Cvt and PMN pathways.

Park J, Kim HI, Jeong H, Lee M, Jang SH, Yoon SY, Kim H, Park ZY, Jun Y, Lee C.

Autophagy. 2019 Sep 12:1-16. doi: 10.1080/15548627.2019.1659615. [Epub ahead of print]


SPIN90, an adaptor protein, alters the proximity between Rab5 and Gapex5 and facilitates Rab5 activation during EGF endocytosis.

Kim H, Oh H, Oh YS, Bae J, Hong NH, Park SJ, Ahn S, Lee M, Rhee S, Lee SH, Jun Y, Kim SH, Huh YH, Song WK.

Exp Mol Med. 2019 Jul 29;51(7):85. doi: 10.1038/s12276-019-0284-5.


The structure of human EXD2 reveals a chimeric 3' to 5' exonuclease domain that discriminates substrates via metal coordination.

Park J, Lee SY, Jeong H, Kang MG, Van Haute L, Minczuk M, Seo JK, Jun Y, Myung K, Rhee HW, Lee C.

Nucleic Acids Res. 2019 Jul 26;47(13):7078-7093. doi: 10.1093/nar/gkz454.


Buforin-1 blocks neuronal SNARE-mediated membrane fusion by inhibiting SNARE complex assembly.

Lee JG, Ko YJ, Choi JH, Jo MJ, Jun Y, Kim JI.

Biochem Biophys Res Commun. 2019 Jun 18;514(1):105-111. doi: 10.1016/j.bbrc.2019.04.124. Epub 2019 Apr 23.


Ergosterol interacts with Sey1p to promote atlastin-mediated endoplasmic reticulum membrane fusion in Saccharomyces cerevisiae.

Lee M, Moon Y, Lee S, Lee C, Jun Y.

FASEB J. 2019 Mar;33(3):3590-3600. doi: 10.1096/fj.201800779RR. Epub 2018 Nov 21.


An In Vitro Assay of Trans-SNARE Complex Formation During Yeast Vacuole Fusion Using Epitope Tag-Free SNAREs.

Jun Y.

Methods Mol Biol. 2019;1860:277-288. doi: 10.1007/978-1-4939-8760-3_18.


T cell microvilli constitute immunological synaptosomes that carry messages to antigen-presenting cells.

Kim HR, Mun Y, Lee KS, Park YJ, Park JS, Park JH, Jeon BN, Kim CH, Jun Y, Hyun YM, Kim M, Lee SM, Park CS, Im SH, Jun CD.

Nat Commun. 2018 Sep 7;9(1):3630. doi: 10.1038/s41467-018-06090-8.


TAGLN2 polymerizes G-actin in a low ionic state but blocks Arp2/3-nucleated actin branching in physiological conditions.

Kim HR, Kwon MS, Lee S, Mun Y, Lee KS, Kim CH, Na BR, Kim BNR, Piragyte I, Lee HS, Jun Y, Jin MS, Hyun YM, Jung HS, Mun JY, Jun CD.

Sci Rep. 2018 Apr 3;8(1):5503. doi: 10.1038/s41598-018-23816-2.


Crystal structures of Mmm1 and Mdm12-Mmm1 reveal mechanistic insight into phospholipid trafficking at ER-mitochondria contact sites.

Jeong H, Park J, Jun Y, Lee C.

Proc Natl Acad Sci U S A. 2017 Nov 7;114(45):E9502-E9511. doi: 10.1073/pnas.1715592114. Epub 2017 Oct 25.


Strategies to Tackle Radiation Resistance by Penetrating Cancer Stem Cell Line of Scrimmage.

Park SY, Kim JY, Jun Y, Nam JS.

Recent Pat Anticancer Drug Discov. 2018;13(1):18-39. doi: 10.2174/1574892812666171003150410. Review.


Molecular mechanisms of atlastin-mediated ER membrane fusion revealed by a FRET-based single-vesicle fusion assay.

Kim KT, Moon Y, Jang Y, Lee KT, Lee C, Jun Y, Lee S.

Sci Rep. 2017 Aug 18;7(1):8700. doi: 10.1038/s41598-017-09162-9.


Roles of Wnt Target Genes in the Journey of Cancer Stem Cells.

Kim JH, Park SY, Jun Y, Kim JY, Nam JS.

Int J Mol Sci. 2017 Jul 25;18(8). pii: E1604. doi: 10.3390/ijms18081604. Review.


The crystal structure of human Rogdi provides insight into the causes of Kohlschutter-Tönz Syndrome.

Lee H, Jeong H, Choe J, Jun Y, Lim C, Lee C.

Sci Rep. 2017 Jun 21;7(1):3972. doi: 10.1038/s41598-017-04120-x.


Mechanistic insight into the nucleus-vacuole junction based on the Vac8p-Nvj1p crystal structure.

Jeong H, Park J, Kim HI, Lee M, Ko YJ, Lee S, Jun Y, Lee C.

Proc Natl Acad Sci U S A. 2017 Jun 6;114(23):E4539-E4548. doi: 10.1073/pnas.1701030114. Epub 2017 May 22.


Structural insights into the interaction of human p97 N-terminal domain and SHP motif in Derlin-1 rhomboid pseudoprotease.

Lim JJ, Lee Y, Yoon SY, Ly TT, Kang JY, Youn HS, An JY, Lee JG, Park KR, Kim TG, Yang JK, Jun Y, Eom SH.

FEBS Lett. 2016 Dec;590(23):4402-4413. doi: 10.1002/1873-3468.12447. Epub 2016 Oct 21.


Structural insights into the interaction of p97 N-terminus domain and VBM in rhomboid protease, RHBDL4.

Lim JJ, Lee Y, Ly TT, Kang JY, Lee JG, An JY, Youn HS, Park KR, Kim TG, Yang JK, Jun Y, Eom SH.

Biochem J. 2016 Sep 15;473(18):2863-80. doi: 10.1042/BCJ20160237. Epub 2016 Jul 12.


Crystal structure of SEL1L: Insight into the roles of SLR motifs in ERAD pathway.

Jeong H, Sim HJ, Song EK, Lee H, Ha SC, Jun Y, Park TJ, Lee C.

Sci Rep. 2016 Feb 9;6:20261. doi: 10.1038/srep20261.


Structural insight for substrate tolerance to 2-deoxyribose-5-phosphate aldolase from the pathogen Streptococcus suis.

Cao TP, Kim JS, Woo MH, Choi JM, Jun Y, Lee KH, Lee SH.

J Microbiol. 2016 Apr;54(4):311-21. doi: 10.1007/s12275-016-6029-4. Epub 2016 Apr 1.


TrpA1 Regulates Defecation of Food-Borne Pathogens under the Control of the Duox Pathway.

Du EJ, Ahn TJ, Kwon I, Lee JH, Park JH, Park SH, Kang TM, Cho H, Kim TJ, Kim HW, Jun Y, Lee HJ, Lee YS, Kwon JY, Kang K.

PLoS Genet. 2016 Jan 4;12(1):e1005773. doi: 10.1371/journal.pgen.1005773. eCollection 2016 Jan.

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