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Items: 1 to 20 of 156


Drug repurposing in alternative medicine: herbal digestive Sochehwan exerts multifaceted effects against metabolic syndrome.

Lim DW, Kim H, Kim YM, Chin YW, Park WH, Kim JE.

Sci Rep. 2019 Jun 21;9(1):9055. doi: 10.1038/s41598-019-45099-x.


Molecular Targets of Genistein and Its Related Flavonoids to Exert Anticancer Effects.

Chae HS, Xu R, Won JY, Chin YW, Yim H.

Int J Mol Sci. 2019 May 16;20(10). pii: E2420. doi: 10.3390/ijms20102420. Review.


Inhibition of Oxidative Neurotoxicity and Scopolamine-Induced Memory Impairment by γ-Mangostin: In Vitro and In Vivo Evidence.

Lee Y, Kim S, Oh Y, Kim YM, Chin YW, Cho J.

Oxid Med Cell Longev. 2019 Mar 24;2019:3640753. doi: 10.1155/2019/3640753. eCollection 2019.


Lonicera japonica extract increases metformin distribution in the liver without change of systemic exposed metformin in rats.

Han SY, Chae HS, You BH, Chin YW, Kim H, Choi HS, Choi YH.

J Ethnopharmacol. 2019 Jun 28;238:111892. doi: 10.1016/j.jep.2019.111892. Epub 2019 Apr 17.


Prenylated Flavonoids from the Roots and Rhizomes of Sophora tonkinensis and Their Effects on the Expression of Inflammatory Mediators and Proprotein Convertase Subtilisin/Kexin Type 9.

Ahn J, Kim YM, Chae HS, Choi YH, Ahn HC, Yoo H, Kang M, Kim J, Chin YW.

J Nat Prod. 2019 Feb 22;82(2):309-317. doi: 10.1021/acs.jnatprod.8b00748. Epub 2019 Jan 30.


Pharmaceutical Impact of Houttuynia Cordata and Metformin Combination on High-Fat-Diet-Induced Metabolic Disorders: Link to Intestinal Microbiota and Metabolic Endotoxemia.

Wang JH, Bose S, Shin NR, Chin YW, Choi YH, Kim H.

Front Endocrinol (Lausanne). 2018 Oct 24;9:620. doi: 10.3389/fendo.2018.00620. eCollection 2018.


7-O-Methylwogonin from Scutellaria baicalensis Disturbs Mitotic Progression by Inhibiting Plk1 Activity in Hep3B Cells.

Woo SU, Jang HR, Chin YW, Yim H.

Planta Med. 2019 Feb;85(3):217-224. doi: 10.1055/a-0731-0394. Epub 2018 Sep 10.


Reducing Effect of Saikosaponin A, an Active Ingredient of Bupleurum falcatum, on Intake of Highly Palatable Food in a Rat Model of Overeating.

Maccioni P, Fara F, Gessa GL, Carai MAM, Chin YW, Lee JH, Kwon HC, Colombo G.

Front Psychiatry. 2018 Aug 13;9:369. doi: 10.3389/fpsyt.2018.00369. eCollection 2018.


Anti-skin ageing effects of phenolic compounds from Carpinus tschonoskii.

Yin J, Ahn HS, Ha SY, Hwang IH, Yoon KD, Chin YW, Lee MW.

Nat Prod Res. 2018 Jul 23:1-4. doi: 10.1080/14786419.2018.1497026. [Epub ahead of print]


A Controlled Fermented Samjunghwan Herbal Formula Ameliorates Non-alcoholic Hepatosteatosis in HepG2 Cells and OLETF Rats.

Ansari A, Bose S, Patra JK, Shin NR, Lim DW, Kim KW, Wang JH, Kim YM, Chin YW, Kim H.

Front Pharmacol. 2018 Jun 19;9:596. doi: 10.3389/fphar.2018.00596. eCollection 2018.


Alpha-Mangostin Improves Insulin Secretion and Protects INS-1 Cells from Streptozotocin-Induced Damage.

Lee D, Kim YM, Jung K, Chin YW, Kang KS.

Int J Mol Sci. 2018 May 16;19(5). pii: E1484. doi: 10.3390/ijms19051484.


Correction: Discovery of a FLT3 inhibitor LDD1937 as an anti-leukemic agent for acute myeloid leukemia.

Lee HJ, Lee J, Jeong P, Choi J, Baek J, Ahn SL, Moon Y, Heo JD, Choi YH, Chin YW, Kim YC, Han SY.

Oncotarget. 2018 Apr 13;9(28):20219. doi: 10.18632/oncotarget.25141. eCollection 2018 Apr 13.


Sauchinone controls hepatic cholesterol homeostasis by the negative regulation of PCSK9 transcriptional network.

Chae HS, You BH, Kim DY, Lee H, Ko HW, Ko HJ, Choi YH, Choi SS, Chin YW.

Sci Rep. 2018 Apr 30;8(1):6737. doi: 10.1038/s41598-018-24935-6.


HO-1 dependent antioxidant effects of ethyl acetate fraction from Physalis alkekengi fruit ameliorates scopolamine-induced cognitive impairments.

Moniruzzaman M, Chin YW, Cho J.

Cell Stress Chaperones. 2018 Jul;23(4):763-772. doi: 10.1007/s12192-018-0887-0. Epub 2018 Mar 15.


Two new lathyrane-type diterpenoid glycosides with IL-6 production inhibitory activity from the roots of Euphorbia kansui.

Kim YM, Ahn J, Chae HS, Choi YH, Kim J, Chin YW.

Bioorg Med Chem Lett. 2018 Apr 15;28(7):1207-1210. doi: 10.1016/j.bmcl.2018.02.050. Epub 2018 Feb 27.


Enzyme Kinetics and Molecular Docking Studies on Cytochrome 2B6, 2C19, 2E1, and 3A4 Activities by Sauchinone.

Gong EC, Chea S, Balupuri A, Kang NS, Chin YW, Choi YH.

Molecules. 2018 Mar 2;23(3). pii: E555. doi: 10.3390/molecules23030555.


Discovery of Flavonoids from Scutellaria baicalensis with Inhibitory Activity Against PCSK 9 Expression: Isolation, Synthesis and Their Biological Evaluation.

Nhoek P, Chae HS, Masagalli JN, Mailar K, Pel P, Kim YM, Choi WJ, Chin YW.

Molecules. 2018 Feb 24;23(2). pii: E504. doi: 10.3390/molecules23020504.


Houttuynia cordata extract increased systemic exposure and liver concentrations of metformin through OCTs and MATEs in rats.

You BH, Chin YW, Kim H, Choi HS, Choi YH.

Phytother Res. 2018 Jun;32(6):1004-1013. doi: 10.1002/ptr.6036. Epub 2018 Feb 26.


Discovery of a FLT3 inhibitor LDD1937 as an anti-leukemic agent for acute myeloid leukemia.

Lee HJ, Lee J, Jeong P, Choi J, Baek J, Ahn SJ, Moon Y, Heo JD, Choi YH, Chin YW, Kim YC, Han SY.

Oncotarget. 2017 Dec 14;9(1):924-936. doi: 10.18632/oncotarget.23221. eCollection 2018 Jan 2. Erratum in: Oncotarget. 2018 Apr 13;9(28):20219.


Nardostachys jatamansi Ethanol Extract Ameliorates Aβ42 Cytotoxicity.

Liu QF, Jeon Y, Sung YW, Lee JH, Jeong H, Kim YM, Yun HS, Chin YW, Jeon S, Cho KS, Koo BS.

Biol Pharm Bull. 2018 Apr 1;41(4):470-477. doi: 10.1248/bpb.b17-00750. Epub 2018 Feb 3.

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