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Items: 1 to 20 of 59

1.

Design of Synthetic Polymer Nanoparticles Specifically Capturing Indole, a Small Toxic Molecule.

Okishima A, Koide H, Hoshino Y, Egami H, Hamashima Y, Oku N, Asai T.

Biomacromolecules. 2019 Apr 8;20(4):1644-1654. doi: 10.1021/acs.biomac.8b01820. Epub 2019 Mar 15.

PMID:
30848887
2.

Rigorous control of vesicle-forming lipid pKa by fluorine-conjugated bioisosteres for gene-silencing with siRNA.

Okamoto A, Koide H, Morita N, Hirai Y, Kawato Y, Egami H, Hamashima Y, Asai T, Dewa T, Oku N.

J Control Release. 2019 Feb 10;295:87-92. doi: 10.1016/j.jconrel.2018.12.044. Epub 2018 Dec 26.

PMID:
30593831
3.

Sequestering and inhibiting a vascular endothelial growth factor in vivo by systemic administration of a synthetic polymer nanoparticle.

Koide H, Yoshimatsu K, Hoshino Y, Ariizumi S, Okishima A, Ide T, Egami H, Hamashima Y, Nishimura Y, Kanazawa H, Miura Y, Asai T, Oku N, Shea KJ.

J Control Release. 2019 Feb 10;295:13-20. doi: 10.1016/j.jconrel.2018.12.033. Epub 2018 Dec 20.

PMID:
30578808
4.

Regio- and chemoselective Csp3-H arylation of benzylamines by single electron transfer/hydrogen atom transfer synergistic catalysis.

Ide T, Barham JP, Fujita M, Kawato Y, Egami H, Hamashima Y.

Chem Sci. 2018 Sep 12;9(44):8453-8460. doi: 10.1039/c8sc02965b. eCollection 2018 Nov 28.

5.

Practical and Scalable Organic Reactions with Flow Microwave Apparatus.

Egami H, Hamashima Y.

Chem Rec. 2019 Jan;19(1):157-171. doi: 10.1002/tcr.201800132. Epub 2018 Dec 4. Review.

PMID:
30511806
6.

C-Alkylation of N-alkylamides with styrenes in air and scale-up using a microwave flow reactor.

Barham JP, Tamaoki S, Egami H, Ohneda N, Okamoto T, Odajima H, Hamashima Y.

Org Biomol Chem. 2018 Nov 7;16(41):7568-7573. doi: 10.1039/c8ob02282h. Epub 2018 Oct 9.

PMID:
30298895
7.

Asymmetric Fluorination of Cyclic Tetrasubstituted Alkenes with a Pendant Amide Groups under Dianionic Phase-Transfer Catalysis.

Niwa T, Ujiie K, Sato H, Egami H, Hamashima Y.

Chem Pharm Bull (Tokyo). 2018;66(10):920-922. doi: 10.1248/cpb.c18-00551.

8.

Enantioselective Synthesis of Nelfinavir via Asymmetric Bromocyclization of Bisallylic Amide.

Nagao Y, Hisanaga T, Utsumi T, Egami H, Kawato Y, Hamashima Y.

J Org Chem. 2018 Jul 6;83(13):7290-7295. doi: 10.1021/acs.joc.8b00039. Epub 2018 Mar 1.

PMID:
29480721
9.

Photofluorination of Aliphatic C-H Bonds Promoted by the Phthalimide Group.

Egami H, Masuda S, Kawato Y, Hamashima Y.

Org Lett. 2018 Mar 2;20(5):1367-1370. doi: 10.1021/acs.orglett.8b00133. Epub 2018 Feb 14.

PMID:
29442520
10.

Dianionic Phase-Transfer Catalyst for Asymmetric Fluoro-cyclization.

Egami H, Niwa T, Sato H, Hotta R, Rouno D, Kawato Y, Hamashima Y.

J Am Chem Soc. 2018 Feb 28;140(8):2785-2788. doi: 10.1021/jacs.7b13690. Epub 2018 Feb 12.

PMID:
29424534
11.

Correction to Synthetic Study on Pactamycin: Stereoselective Synthesis of the Cyclopentane Core Framework.

Goto A, Yoshimura S, Nakao Y, Inai M, Asakawa T, Egi M, Hamashima Y, Kondo M, Kan T.

Org Lett. 2018 Feb 2;20(3):896. doi: 10.1021/acs.orglett.7b04009. Epub 2018 Jan 24. No abstract available.

PMID:
29363976
12.

Desymmetrization of Bisallylic Amides through Catalytic Enantioselective Bromocyclization with BINAP Monoxide.

Nagao Y, Hisanaga T, Egami H, Kawato Y, Hamashima Y.

Chemistry. 2017 Nov 27;23(66):16758-16762. doi: 10.1002/chem.201704847. Epub 2017 Nov 6.

PMID:
29044749
13.

Benzylic C-H Trifluoromethylation via Photoenol.

Ide T, Masuda S, Kawato Y, Egami H, Hamashima Y.

Org Lett. 2017 Sep 1;19(17):4452-4455. doi: 10.1021/acs.orglett.7b01971. Epub 2017 Aug 11.

PMID:
28799765
14.

Total Synthesis of TAN1251C via Diastereoselective Construction of the Azaspiro Skeleton.

Nagasaka Y, Shintaku S, Matsumura K, Masuda A, Asakawa T, Inai M, Egi M, Hamashima Y, Ishikawa Y, Kan T.

Org Lett. 2017 Jul 21;19(14):3839-3842. doi: 10.1021/acs.orglett.7b01718. Epub 2017 Jun 29.

PMID:
28661151
15.

Synthetic Study on Pactamycin: Stereoselective Synthesis of the Cyclopentane Core Framework.

Goto A, Yoshimura S, Nakao Y, Inai M, Asakawa T, Egi M, Hamashima Y, Kondo M, Kan T.

Org Lett. 2017 Jul 7;19(13):3358-3361. doi: 10.1021/acs.orglett.7b01257. Epub 2017 Jun 12. Erratum in: Org Lett. 2018 Feb 2;20(3):896.

PMID:
28604005
16.

Stereoselective construction of 2-vinyl 3-hydroxybenzopyran rings: total syntheses of teadenols A and B.

Yoshida R, Ouchi H, Yoshida A, Asakawa T, Inai M, Egi M, Hamashima Y, Kan T.

Org Biomol Chem. 2016 Nov 22;14(46):10783-10786.

PMID:
27808327
17.

Difunctionalization of Alkenes Using 1-Chloro-1,2-benziodoxol-3-(1H)-one.

Egami H, Yoneda T, Uku M, Ide T, Kawato Y, Hamashima Y.

J Org Chem. 2016 May 20;81(10):4020-30. doi: 10.1021/acs.joc.6b00295. Epub 2016 Apr 28.

PMID:
27100051
18.

Practical Total Syntheses of Acromelic Acids A and B.

Inai M, Ouchi H, Asahina A, Asakawa T, Hamashima Y, Kan T.

Chem Pharm Bull (Tokyo). 2016 Jul 1;64(7):723-32. doi: 10.1248/cpb.c16-00009. Epub 2016 Feb 24.

19.

Syntheses of methylated catechins and theaflavins using 2-nitrobenzenesulfonyl group to protect and deactivate phenol.

Asakawa T, Kawabe Y, Yoshida A, Aihara Y, Manabe T, Hirose Y, Sakurada A, Inai M, Hamashima Y, Furuta T, Wakimoto T, Kan T.

J Antibiot (Tokyo). 2016 Apr;69(4):299-312. doi: 10.1038/ja.2016.14. Epub 2016 Feb 24.

PMID:
26905756
20.

Highly Enantioselective Bromocyclization of Allylic Amides with a P/P=O Double-Site Lewis Base Catalyst.

Kawato Y, Ono H, Kubota A, Nagao Y, Morita N, Egami H, Hamashima Y.

Chemistry. 2016 Feb;22(6):2127-2133. doi: 10.1002/chem.201503153. Epub 2016 Jan 7.

PMID:
26743540

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