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Items: 1 to 20 of 22


Sesame Lignans Suppress Age-Related Cognitive Decline in Senescence-Accelerated Mice.

Shimoyoshi S, Takemoto D, Ono Y, Kitagawa Y, Shibata H, Tomono S, Unno K, Wakabayashi K.

Nutrients. 2019 Jul 12;11(7). pii: E1582. doi: 10.3390/nu11071582.


Sesamin Catechol Glucuronides Exert Anti-inflammatory Effects by Suppressing Interferon β and Inducible Nitric Oxide Synthase Expression through Deconjugation in Macrophage-like J774.1 Cells.

Abe-Kanoh N, Kunimoto Y, Takemoto D, Ono Y, Shibata H, Ohnishi K, Kawai Y.

J Agric Food Chem. 2019 Jul 10;67(27):7640-7649. doi: 10.1021/acs.jafc.8b07227. Epub 2019 Apr 16.


Mechanisms of chromosomal aberrations induced by sesamin metabolites in Chinese hamster lung cells.

Ono Y, Tomimori N, Hori H, Kitagawa Y, Shibata H.

Mutat Res. 2017 Oct;822:19-26. doi: 10.1016/j.mrgentox.2017.06.006. Epub 2017 Jun 30.


Glucosamine-containing supplement improves locomotor functions in subjects with knee pain: a randomized, double-blind, placebo-controlled study.

Kanzaki N, Ono Y, Shibata H, Moritani T.

Clin Interv Aging. 2015 Oct 28;10:1743-53. doi: 10.2147/CIA.S93077. eCollection 2015.


Sesamin prevents decline in exercise capacity and impairment of skeletal muscle mitochondrial function in mice with high-fat diet-induced diabetes.

Takada S, Kinugawa S, Matsushima S, Takemoto D, Furihata T, Mizushima W, Fukushima A, Yokota T, Ono Y, Shibata H, Okita K, Tsutsui H.

Exp Physiol. 2015 Nov;100(11):1319-30. doi: 10.1113/EP085251. Epub 2015 Oct 1.


Sesame Lignans and Vitamin E Supplementation Improve Subjective Statuses and Anti-Oxidative Capacity in Healthy Humans With Feelings of Daily Fatigue.

Takemoto D, Yasutake Y, Tomimori N, Ono Y, Shibata H, Hayashi J.

Glob J Health Sci. 2015 Mar 25;7(6):1-10. doi: 10.5539/gjhs.v7n6p1.


The effect of the sympathetic nervous system on splenic natural killer cell activity in mice administered the Lactobacillus pentosus strain S-PT84.

Izumo T, Maekawa T, Horii Y, Fujisaki Y, Ida M, Furukawa Y, Ono Y, Kiso Y, Kitagawa Y, Shibata H, Nagai K.

Neuroreport. 2013 Dec 4;24(17):988-91. doi: 10.1097/WNR.0000000000000036.


Evaluation of antioxidative effects of sesamin on the in vivo hepatic reducing abilities by a radiofrequency ESR method.

Tada M, Ono Y, Nakai M, Harada M, Shibata H, Kiso Y, Ogata T.

Anal Sci. 2013;29(1):89-94.


Identification of the metabolites of episesamin in rat bile and human liver microsomes.

Tomimori N, Nakai M, Ono Y, Kitagawa Y, Kiso Y, Shibata H.

Biol Pharm Bull. 2012;35(5):709-16.


Interrelated effects of dihomo-γ-linolenic and arachidonic acids, and sesamin on hepatic fatty acid synthesis and oxidation in rats.

Ide T, Ono Y, Kawashima H, Kiso Y.

Br J Nutr. 2012 Dec 14;108(11):1980-93. doi: 10.1017/S0007114512000141. Epub 2012 Feb 28.


1,5-Anhydro-D-fructose: A natural antibiotic that inhibits the growth of gram-positive bacteria and microbial biofilm formation to prevent nosocomial infection.

Meng X, Kawahara KI, Miyanohara H, Yoshimoto Y, Yoshinaga K, Noma S, Kikuchi K, Morimoto Y, Ito T, Oyama Y, Yoshinaga N, Shrestha B, Chandan B, Mera K, Tada KI, Miura N, Ono Y, Takenouchi K, Maenosono R, Nagasato T, Hashiguchi T, Maruyama I.

Exp Ther Med. 2011 Jul;2(4):625-628. Epub 2011 Apr 1.


Involvement of heme oxygenase-1 induction via Nrf2/ARE activation in protection against H2O2-induced PC12 cell death by a metabolite of sesamin contained in sesame seeds.

Hamada N, Tanaka A, Fujita Y, Itoh T, Ono Y, Kitagawa Y, Tomimori N, Kiso Y, Akao Y, Nozawa Y, Ito M.

Bioorg Med Chem. 2011 Mar 15;19(6):1959-65. doi: 10.1016/j.bmc.2011.01.059. Epub 2011 Feb 2.


Genotoxicity evaluation of sesamin and episesamin.

Hori H, Takayanagi T, Kamada Y, Shimoyoshi S, Ono Y, Kitagawa Y, Shibata H, Nagao M, Fujii W, Sakakibara Y.

Mutat Res. 2011 Feb 3;719(1-2):21-8. doi: 10.1016/j.mrgentox.2010.10.001. Epub 2010 Oct 16. Erratum in: Mutat Res. 2011 Apr 3;721(2):211.


Metabolites of sesamin, a major lignan in sesame seeds, induce neuronal differentiation in PC12 cells through activation of ERK1/2 signaling pathway.

Hamada N, Fujita Y, Tanaka A, Naoi M, Nozawa Y, Ono Y, Kitagawa Y, Tomimori N, Kiso Y, Ito M.

J Neural Transm (Vienna). 2009 Jul;116(7):841-52. doi: 10.1007/s00702-009-0250-9. Epub 2009 Jun 16.


First chemical synthesis of antioxidative metabolites of sesamin.

Urata H, Nishioka Y, Tobashi T, Matsumura Y, Tomimori N, Ono Y, Kiso Y, Wada S.

Chem Pharm Bull (Tokyo). 2008 Nov;56(11):1611-2.


Dietary tocotrienol reduces UVB-induced skin damage and sesamin enhances tocotrienol effects in hairless mice.

Yamada Y, Obayashi M, Ishikawa T, Kiso Y, Ono Y, Yamashita K.

J Nutr Sci Vitaminol (Tokyo). 2008 Apr;54(2):117-23.

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